Clerodendrum serratum (L.) Moon, Clerodendrum serratum var. amplexifolium Moldenke, Clerodendrum serratum var. glabrescens Moldenke, Clerodendrum serratum f. lacteum Moldenke, Clerodendrum serratum var. nepalense Moldenke, Clerodendrum serratum var. obovatum Moldenke, Clerodendrum serratum var. pilosum Moldenke, Clerodendrum serratum var. velutinum Moldenke, Clerodendrum serratum var. wallichii C.B.Clarke
Kingdom
Plantae
Subkingdom
Superdivision
--
Division
Tracheophyta
Class
Magnoliopsida
Subclass
Order
Lamiales
Family
Lamiaceae
Genus
Rotheca Raf.
Species
Clerodendrum serratum (L.) Moon
Shrub
Peninsular India, Western Ghats & Eastern Ghats, Western and Eastern Himalaya, Uttarakhand , West Bengal, Bihar
-
-
Rheumatism, anorexia, cough, asthma, hiccough, tubercular glands, skin diseases hepatoprotective, headache,piles, blood purifier, stomach ache, scabies, diabetes, jaundice, bood pressure
1. Localites of Rayalaseema Region of Southern Eastern Ghats, Andhra Pradesh, India uses Bark of Clerodendrum serratum is used to treat fractures.
Rao, Dowlathabad Muralidhara; Rao, U.V.U. Bhaskara; and Sudharshanam, G. (2006) "Ethno-Medico-Botanical Studies From Rayalaseema Region of Southern Eastern Ghats, Andhra Pradesh, India," Ethnobotanical Leaflets: Vol. 2006 : Iss. 1 , Article 21.
Available at: https://opensiuc.lib.siu.edu/ebl/vol2006/iss1/21
2.Locally known as Bharangi, Leaves are used to cure Respiratory disorders and Eye problems. Jadhav, D. M., Padwal, S. G., & Jadhav, A. H. (2023). ETHNOBOTANICAL DOCUMENTATION OF LAMIACEAE FLORA FROM KINWAT AND MAHUR REGION OF NANDED DISTRICT, MAHARASHTRA STATE (INDIA).
3.T Jaintia tribes in North Cachar Hills district of Assam, northeast India, uses whole part grounded with water to prepare a paste to cure fever.
Sajem, A. L., & Gosai, K. (2006). Traditional use of medicinal plants by the Jaintia tribes in North Cachar Hills district of Assam, northeast India. Journal of ethnobiology and ethnomedicine, 2(1), 1-7.
4. Ointment made from leaves boiled with oil and butter is used in cephalaria and snekebites.
Shukla, A. N., Srivastava, S., & Rawat, A. K. S. (2010). An ethnobotanical study of medicinal plants of Rewa district, Madhya Pradesh.
5. Roots crushed with that of Rauwolfia serpentina and the filtrate is adviced to consume for fever stomach pain and menstrual disorders .
Wagay, N. A., Rafiq1&2, S., Gazi, M. A., Maheshwari, A. A., Ahmad, N., Khalid, L. P., & Pulate, P. V. (2019). Exploration, assessment and ethnobotanical studies of tribe Korku inhabited in Melghat Forest Area of Amravati, Maharashtra, India. Research Journal of life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences (RJLBPCS), 5(2), 549-571.
6. Leaves are used for cure of headache by brushing around the forehead.
7. Roots used in rheumatism and dyspepsia. Leaves used as febrifuge, also as an external application in cephaigia and opthlmia. Seeds aperients, used in dropsy.
Gritto, M. J., Nandagopalan, V., & Doss, A. (2015). Ethno-botanical study on the traditional healers in Pachamalai hills of Eastern Ghats, Tamilnadu, South India. J Med Plants Stud, 3(2), 80-85.
8. Tribes of Nambor reserve forest, Assam, uses herbs in various ways, Leaf extract is used to cure seasonal fever, Decoction of leaves are given for treating fever. Root paste is used to cure rheumatism.
Yadav, A., Verma, P. K., Chand, T., & Bora, H. R. (2018). Ethno-medicinal knowledge of Clerodendrum L. among different tribes of Nambor reserve forest, Assam, India. Journal of Pharmacognosy and Phytochemistry, 7(5), 1567-1570.
9. Leave paste of Clerodendrum serratum and Adhatoda zeylanica mixed with powder of Piper longum is taken orally to cure asthma.
Rajakumar, N., & Shivanna, M. B. (2010). Traditional herbal medicinal knowledge in Sagar taluk of Shimoga district, Karnataka, India.
10. Roots are consumed to cure variety of ailments: bronchitis, asthma, fever, blood diseases, tumors, inflammations, burning sensation, epilepsy, malaria, ulcer and wounds.
S.M. Vidya, V. Krishna, B.K. Manjunatha, K.L. Mankani, M. Ahmed, S.D.J. Singh, Evaluation of hepatoprotective activity of Clerodendrum serratum L., Indian Journal of Experimental Biology, 45 (2007), pp. 538-542
11. The root juice of herb with ginger is used to relieve bronchospasms in asthma and reduce the attacks of dyspnea . Root powder is given along with sugar to cure hiccough.
12. The decoction of root is highly in edema and worm infestations .Decoction of sesame seeds mixed with ghee, jaggery, C. serratum root powder and trikatu powder (Ayurvedic formula with equal proportion of three drugs viz. rhizomes of Zinziber officinale Roscoe., Zingiberaceae and fruits of Piper longum Linn. and Piper nigrum L., Piperaceae) is used as the remedy for amenorrhea and uterine tumor.
P.C. Sharma, M.B. Yelne, T.J. Dennis, Data base on medicinal plants used in Ayurveda, vol. I, Ministry of Health and Family Welfare, Government of India, New Delhi (2002), p. 74
13. Owing to its Snigdha and Madhura nature, it acts as an expectorant and useful in hiccough and hoarseness of voice. The combination of Bharangi and Pippali (2:1) with honey is an effective remedy for hiccough.
14. A piece of the root is kept in a small brass container and used as talisman on the left arm of woman and right arm of the man with a view that poisonous snakes do not bite the talisman bearer.
| # | Phytochemical Constituents | PUBCHEM CID | References |
|---|---|---|---|
| 1 | Apigenin | 5280443 | Salehi B, Venditti A, Sharifi-Rad M, Kręgiel D, Sharifi-Rad J, Durazzo A, Lucarini M, Santini A, Souto EB, Novellino E, Antolak H, Azzini E, Setzer WN, Martins N. The Therapeutic Potential of Apigenin. Int J Mol Sci. 2019 Mar 15;20(6):1305. doi: 10.3390/ijms20061305. PMID: 30875872; PMCID: PMC6472148. |
| 2 | Oleanolic acid | 10494 | Pollier J, Goossens A. Oleanolic acid. Phytochemistry. 2012 May;77:10-5. doi: 10.1016/j.phytochem.2011.12.022. Epub 2012 Feb 28. PMID: 22377690.Lin C, Wen X, Sun H. Oleanolic acid derivatives for pharmaceutical use: a patent review. Expert Opin Ther Pat. 2016 Jun;26(6):643-55. doi: 10.1080/13543776.2016.1182988. Epub 2016 May 10. PMID: 27113324. |
| 3 | Queretaroic acid | 12314864 | Fujii Y, Hirosue S, Fujii T, Matsumoto N, Agematu H, Arisawa A. Hydroxylation of oleanolic acid to queretaroic acid by cytochrome P450 from Nonomuraea recticatena. Biosci Biotechnol Biochem. 2006 Sep;70(9):2299-302. doi: 10.1271/bbb.60126. Epub 2006 Sep 7. PMID: 16960364. |
| 4 | Serratagenic acid | 21594175 | Luo Y, Liu H, Yin X, Ye X, Kang L. [Chemical constituents contained in Macropanax rosthornii]. Zhongguo Zhong Yao Za Zhi. 2012 Jul;37(13):1977-80. Chinese. PMID: 23019882. |
| 5 | Ursolic acid | 64945 | Khwaza V, Oyedeji OO, Aderibigbe BA. Ursolic Acid-Based Derivatives as Potential Anti-Cancer Agents: An Update. Int J Mol Sci. 2020 Aug 18;21(16):5920. doi: 10.3390/ijms21165920. PMID: 32824664; PMCID: PMC7460570. |
| 6 | Icosahydropicenic acid | 156025606 | Patel JJ, Acharya SR, Acharya NS. Clerodendrum serratum (L.) Moon. - a review on traditional uses, phytochemistry and pharmacological activities. J Ethnopharmacol. 2014 Jun 11;154(2):268-85. doi: 10.1016/j.jep.2014.03.071. Epub 2014 Apr 13. PMID: 24727551. |
| 7 | Serratin | 5398649 | Bouarab L, Degraeve P, Bouajila J, Cottaz A, Jbilou F, Joly C, Oulahal N. Staphylococcus aureus membrane-damaging activities of four phenolics. FEMS Microbiol Lett. 2021 Jul 9;368(13):fnab081. doi: 10.1093/femsle/fnab081. PMID: 34173656. |
| 8 | β-sitosterol | 175268335 | Babu S, Jayaraman S. An update on β-sitosterol: A potential herbal nutraceutical for diabetic management. Biomed Pharmacother. 2020 Nov;131:110702. doi: 10.1016/j.biopha.2020.110702. Epub 2020 Aug 31. PMID: 32882583. |
| 9 | ɣ-sitosterol | 9548595 | Shefer S, Salen G, Nguyen L, Batta AK, Packin V, Tint GS, Hauser S. Competitive inhibition of bile acid synthesis by endogenous cholestanol and sitosterol in sitosterolemia with xanthomatosis. Effect on cholesterol 7 alpha-hydroxylase. J Clin Invest. 1988 Dec;82(6):1833-9. doi: 10.1172/JCI113799. PMID: 3143743; PMCID: PMC442761. |
| 10 | Spinasterol | 5281331 | Majeed M, Ahmad F, Mundkur L, Appian S. Pharmacology of α-spinasterol, a phytosterol with nutraceutical values: A review. Phytother Res. 2022 Oct;36(10):3681-3690. doi: 10.1002/ptr.7560. Epub 2022 Jul 8. PMID: 35802356. |
| 11 | (þ)-catechin | 6419835 | Sato K, Saito S, Endo K, Kono M, Kakei T, Taketa H, Kato M, Hamamoto S, Grenzi M, Costa A, Munemasa S, Murata Y, Ishimaru Y, Uozumi N. Green Tea Catechins, (-)-Catechin Gallate, and (-)-Gallocatechin Gallate are Potent Inhibitors of ABA-Induced Stomatal Closure. Adv Sci (Weinh). 2022 Jul;9(21):e2201403. doi: 10.1002/advs.202201403. Epub 2022 May 7. PMID: 35524639; PMCID: PMC9313475. |
| 12 | Caffeic acid | 689043 | Muhammad Abdul Kadar NN, Ahmad F, Teoh SL, Yahaya MF. Caffeic Acid on Metabolic Syndrome: A Review. Molecules. 2021 Sep 9;26(18):5490. doi: 10.3390/molecules26185490. PMID: 34576959; PMCID: PMC8465857. |
| 13 | Ferulic acid | 445858 | Li D, Rui YX, Guo SD, Luan F, Liu R, Zeng N. Ferulic acid: A review of its pharmacology, pharmacokinetics and derivatives. Life Sci. 2021 Nov 1;284:119921. |
| 14 | Myricoside | 5281784 | Caliş I, Bedir E, Kirmizibekmez H, Ersöz T, Dönmez AA, Khan IA. Secondary metabolites from Phlomis oppositiflora. Nat Prod Res. 2005 Jul;19(5):493-501. doi: 10.1080/14786410412331280069. PMID: 15938195. |
| 15 | Acteoside | 5281800 | Guo J, Liu QZ, Zhu FJ, Li M, Li J, Guo L, Sun QY, Yang QX. Acteoside attenuates acute lung injury following administration of cobra venom factor to mice. Heliyon. 2022 Nov 14;8(11):e11622. doi: 10.1016/j.heliyon.2022.e11622. PMID: 36411899; PMCID: PMC9674544. |
| 16 | Luteolin | 5280445 | Gendrisch F, Esser PR, Schempp CM, Wölfle U. Luteolin as a modulator of skin aging and inflammation. Biofactors. 2021 Mar;47(2):170-180. doi: 10.1002/biof.1699. Epub 2020 Dec 25. PMID: 33368702. |
| 17 | Scutellarein | 5281697 | Ushakou D, Wróblewski T. Scutellarein in organic solvents: changes in spectroscopic properties caused by solute-solvent interactions. Spectrochim Acta A Mol Biomol Spectrosc. 2022 May 15;273:121027. doi: 10.1016/j.saa.2022.121027. Epub 2022 Feb 12. PMID: 35182824. |
| # | PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES | REFERENCES |
|---|---|---|
| 1 | Hepatoprotective activity | Poornima BS, Prakash L Hegde, Pradeep, Harini A. Pharmacological review on Clerodendrum serratum Linn. Moon. J Pharmacogn Phytochem 2015;3(5):126-130. DOI: https://dx.doi.org/10.22271 NASRUDIN, Nasrudin et al. Hepatoprotective Activity of Ethyl Acetate Fraction of Senggugu’s Root Bark (Clerodendrum serratum L.Moon) on Rats Induced by CCl4. Indonesian Journal of Pharmacy, [S.l.], p. 10, aug. 2017. ISSN 2338-9486. Vidya, S M ,Krishna, V,Manjunatha, B K, Mankani, K L,Ahmed, Manzoor, Singh, S D Jagadeesh, Evaluation of hepatoprotective activity of Clerodendrum serratum L. IJEB Vol.45(06) [June 2007] Page(s)538-542ISSN: 0975-1009 (Online); 0019-5189, http://nopr.niscpr.res.in/handle/123456789/5276. Patel, Jagruti J., Sanjeev R. Acharya, and Niyati S. Acharya. "Clerodendrum serratum (L.) Moon.–A review on traditional uses, phytochemistry and pharmacological activities." Journal of ethnopharmacology 154.2 (2014): 268-285. Kumar, Praveen, and K. Nishteswar. "Phytochemical and pharmacological profiles of Clerodendrum serratum linn.(bharngi): a review." Int. J. Res. Ayurveda Pharm 4.2 (2013): 276-278. Tulsiani, Puja. "Hepatoprotective Acitivity of a Polyherbal Formaltion: A histological study." Asian Journal of Complementary and Alternative Medicine 1.01 (2013): 24-26. Begum, T. Nargis, MH Muhammad Ilyas, and A. Vijaya Anand. "Hepatoprotective activity of Azima tetracantha Lam. in experimental animals." Journal of Pharmacy Research 4.7 (2011): 2359-2360. Gauri Dongare , Akshada Kale , Pranali Band , Ashwini Chavan , Dr. A. N. Aher and Sonali Gawali, A REVIEW ON PHYTOCHEMICAL AND PHARMACOLOGICAL ACTION OF CLERODENDRUM SERRATUM LINN. (BHARANGI), World Journal of Pharmaceutical Research 2020,Volume 9, Issue 12, 229-236. ISSN 2277– 7105. |
| 2 | Antioxidant activity | S.S B, S.M.K. K, L.S M, M.J P. Antioxidant Effects of Roots of Clerodendrum serratum Linn. Pharmacognosy Research. 2009;1(5):294-298. Mohamed, A. J., Mohamed, E. A. H., Aisha, A. F., Ameer, O. Z., Ismail, Z., Ismail, N., & Yam, M. F. Antioxidant, antiangiogenic and vasorelaxant activities of methanolic extract of Clerodendrum serratum (Spreng.) leaves. Journal of Medicinal Plants Research, 6(3), 348-360, 23 january 2012 DOI: 10.5897/JMPR11.049 Jagruti J. Patel, Sanjeev R. Acharya, Niyati S. Acharya,Clerodendrum serratum (L.) Moon. – A review on traditional uses,phytochemistry and pharmacological activities, Journal of Ethnopharmacology, Volume 154, Issue 2,2014, Pages 268-285, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2014.03.071. Prasad M.P., Sushant S. and Chikkaswamy B.K Phytochemical Analysis, Antioxidant Potential, Antibacterial Activity and Molecular Characterization of Clerodendrum species. International Journal of Molecular Biology, ISSN: 0976-0482 & E-ISSN: 0976-0490, (2012) Vol ume 3, Issue 3, pp.-71-76. Kajaria DK, Gangwar M, Sharma AK, Tripathi YB, Tripathi JS, Tiwari S. Evaluation of in vitro antioxidant capacity and reducing potential of polyherbal drug- Bhāraṅgyādi. Anc Sci Life. 2012 Jul;32(1):24-8. doi: 10.4103/0257-7941.113798. PMID: 23929990; PMCID: PMC3733202. Kar, Pallab, et al. "Antioxidant and pharmaceutical potential of Clerodendrum L.: An overview." International Journal of Green Pharmacy (IJGP) 8.4 (2014). Shareef, M. I., and S. Leelavathi. "Evaluation of antioxidant activity of Anisolmeles malabarica R Br and Clerodendrum serratum L. extracts against rheumatism." Research Journal of Pharmaceutical, Biological and Chemical Sciences 2.4 (2011): 488-495. Prasad, M. P., S. Sushant, and B. K. Chikkaswamy. "Phytochemical analysis, antioxidant potential, antibacterial activity and molecular characterization of Clerodendrum species." International journal of molecular biology 3.3 (2012): 71-76. Kajaria, Divya Kumari, et al. "Evaluation of in vitro antioxidant capacity and reducing potential of polyherbal drug-Bhāraṅgyādi." Ancient science of life 32.1 (2012): 24. Poornima, B. S., Prakash L. Hegde, and A. Harini. "Pharmacological review on Clerodendrum serratum Linn. Moon." Journal of Pharmacognosy and Phytochemistry 3.5 (2015): 126-130. |
| 3 | Anticancer activity | Bhangare, N. K., Pansare, T. A., Ghongane, B. B., & Nesari, T. M. Screening for anti-inflammatory and anti-allergic activity of Bharangi {Clerodendrum serrratum (Linn.) moon} in animals. International journal of pharma and bio sciences, 3(4).2012 Poornima BS, Prakash L Hegde, Pradeep, Harini A. Pharmacological review on Clerodendrum serratum Linn. Moon. J Pharmacogn Phytochem 2015;3(5):126-130. DOI: https://dx.doi.org/10.22271 Jagruti J. Patel, Sanjeev R. Acharya, Niyati S. Acharya, Clerodendrum serratum (L.) Moon. – A review on traditional uses, phytochemistry and pharmacological activities, Journal of Ethnopharmacology, Volume 154, Issue 2, 2014, Pages 268-285,I SSN 0378 8741,https://doi.org/10.1016/j.jep.2014.03.071. Gogoi B, Gogoi D, Silla Y, Kakoti BB, Bhau BS. Network pharmacology-based virtual screening of natural products from Clerodendrum species for identification of novel anti-cancer therapeutics. Mol Biosyst. 2017 Jan 31;13(2):406-416. doi: 10.1039/c6mb00807k. PMID: 28070575. Ramya Priyadharshini Raman, Sujitha Parthiban, B. Srinithya, V. Vinod Kumar, Savarimuthu Philip Anthony, Aravind Sivasubramanian, Meenakshi Sundaram Muthuraman, Biogenic silver nanoparticles synthesis using the extract of the medicinal plant Clerodendron serratum and its in-vitro antiproliferative activity, Materials Letters, Volume 160, 2015, Pages 400-403, ISSN 0167-577X,https://doi.org/10.1016/j.matlet.2015.08.009. Mahajan H, Singh Arora D, Singh H, Jain SK, Namarta K, Singh J. Scientific validation of the antimicrobial and antiproliferative potential of Clerodendrum serratum (L.) Moon, its phytoconstituents and their biosafety by acute oral toxicity study. Drug Chem Toxicol. 2021 Nov;44(6):620-630. doi: 10.1080/01480545.2019.1643875. Epub 2019 Aug 1. PMID: 31368375. Zalke, Ashish S., et al. "In vivo anticancer activity of Clerodendrum serratum (L) moon." Research Journal of Pharmaceutical Biological and Chemical Sciences 1.3 (2010): 89-98. Kumar, Praveen, and K. Nishteswar. "Phytochemical and pharmacological profiles of Clerodendrum serratum linn.(bharngi): a review." Int. J. Res. Ayurveda Pharm 4.2 (2013): 276-278. Kar, Pallab, et al. "Antioxidant and pharmaceutical potential of Clerodendrum L.: An overview." International Journal of Green Pharmacy (IJGP) 8.4 (2014). Sriranjani, R., et al. "Silver nanoparticle synthesis using Clerodendrum phlomidis leaf extract and preliminary investigation of its antioxidant and anticancer activities." Journal of Molecular Liquids 220 (2016): 926-930 |
| 4 | Anti nociceptive activity | Narayanan N, Thirugnanasambantham P, Viswanathan S, Vijayasekaran V, Sukumar E. Antinociceptive, anti-inflammatory and antipyretic effects of ethanol extract of Clerodendron serratum roots in experimental animals. J Ethnopharmacol. 1999 Jun;65(3):237-41. doi: 10.1016/s0378-8741(98)00176-7. PMID: 10404422. Patel JJ, Acharya SR, Acharya NS. Clerodendrum serratum (L.) Moon. - a review on traditional uses, phytochemistry and pharmacological activities. J Ethnopharmacol. 2014 Jun 11;154(2):268-85. doi: 10.1016/j.jep.2014.03.071. Epub 2014 Apr 13. PMID: 24727551. Sharma, M., Rai, S.K., Purshottam, D.K. et al. In vitro clonal propagation of Clerodendrum serratum (Linn.) Moon (barangi): a rare and threatened medicinal plant. Acta Physiol Plant 31, 379–383 (2009). https://doi.org/10.1007/s11738-008-0245-4 Poornima, B. S., Prakash L. Hegde, and A. Harini. "Pharmacological review on Clerodendrum serratum Linn. Moon." Journal of Pharmacognosy and Phytochemistry 3.5 (2015): 126-130. |
| 5 | Anti-inflammatory activity | Bhangare, N. K., Pansare, T. A., Ghongane, B. B., & Nesari, T. M. Screening for anti-inflammatory and anti-allergic activity of Bharangi {Clerodendrum serrratum (Linn.) moon} in animals. International journal of pharma and bio sciences, 3(4).2012 Patel, J. J., Acharya, S. R., & Acharya, N. S. (2014). Clerodendrum serratum (L.) Moon.–A review on traditional uses, phytochemistry and pharmacological activities. Journal of ethnopharmacology, 154(2), 268-285. Dongare, G., Kale, A., Band, P., Chavan, A., Aher, A. N., & Gawali, S. (2020). A REVIEW ON PHYTOCHEMICAL AND PHARMACOLOGICAL ACTION OF CLERODENDRUM SERRATUM LINN.(BHARANGI) Divya, K., Tripathi, J. S., & Tiwari, S. K. Study of antiasthmatic properties and chemical characterization of indigenous ayurvedic compounds (polyherbal formulations). American Journal of Phytomedicine and Clinical Therapeutics, (2013).6(1), 457-466. Lee Yen Sim, Nur Zahirah Abd Rani and Khairana Husain Lamiaceae: An Insight on Their Anti-Allergic Potential and Its Mechanisms of Action, Front. Pharmacol., 19 June 2019 Sec. Ethnopharmacology Volume 10 - 2019 | https://doi.org/10.3389/fphar.2019.00677. Singh, Mukesh Kr, et al. "Clerodendrum serratum: A clinical approach." Journal of Applied Pharmaceutical Science Issue (2012): 11-15. Poornima, B. S., Prakash L. Hegde, and A. Harini. "Pharmacological review on Clerodendrum serratum Linn. Moon." Journal of Pharmacognosy and Phytochemistry 3.5 (2015): 126-130. Kumar, Praveen, and K. Nishteswar. "Phytochemical and pharmacological profiles of Clerodendrum serratum linn.(bharngi): a review." Int. J. Res. Ayurveda Pharm 4.2 (2013): 276-278. Tiwari, Raj Kumar, et al. "Anti-inflammatory and anti-arthritic potential of standardized extract of Clerodendrum serratum (L.) Moon." Frontiers in Pharmacology 12 (2021): 629607 Hafiz, Ihsanul, and Silalahi J. Rosidah. "Antioxidant and anti-inflammatory activity of pagoda leaves (clerodendrum paniculatum l.) ethanolic extract in white male rats (Rattus novergicus)." International Journal of PharmTech Research 9.5 (2016): 165-170. Kar, Pallab, et al. "Antioxidant and pharmaceutical potential of Clerodendrum L.: An overview." International Journal of Green Pharmacy (IJGP) 8.4 (2014). |
| 6 | Anti- pyretic activity | Narayanan N, Thirugnanasambantham P, Viswanathan S, Vijayasekaran V, Sukumar E. Antinociceptive, anti-inflammatory and antipyretic effects of ethanol extract of Clerodendron serratum roots in experimental animals. J Ethnopharmacol. 1999 Jun;65(3):237-41. doi: 10.1016/s0378-8741(98)00176-7. PMID: 10404422. Solapure P, Pradeep, Mundugaru R, Hegde PL. Comparative anti-inflammatory activity of Clerodendrum serratum (Linn) Moon and Solanum xanthocarpum Schrad and Wendl in wistar ablino rats. The Journal of Phytopharmacology 2016;5(2):38-44. Poornima, B. S., Prakash L. Hegde, and A. Harini. "Pharmacological review on Clerodendrum serratum Linn. Moon." Journal of Pharmacognosy and Phytochemistry 3.5 (2015): 126-130. Sultana, Sabira, et al. "Medicinal plants with potential antipyretic activity: A review." Asian Pacific Journal of Tropical Disease 5 (2015): S202-S208. |
| 7 | Anti fungal activity | Gupta, R., Bajpai, K. G., Johri, S., & Saxena, A. M. (2007). AN OVERVIEW OF INDIAN NOVEL TRADITIONAL MEDICINAL PLANTS WITH ANTI-DIABETIC POTENTIALS. African Journal of Traditional, Complementary and Alternative Medicines, 5(1), 1–17. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/321 Mahajan H, Singh Arora D, Singh H, Jain SK, Namarta K, Singh J. Scientific validation of the antimicrobial and antiproliferative potential of Clerodendrum serratum (L.) Moon, its phytoconstituents and their biosafety by acute oral toxicity study. Drug Chem Toxicol. 2021 Nov;44(6):620-630. doi: 10.1080/01480545.2019.1643875. Epub 2019 Aug 1. PMID: 31368375 Singh, Mukesh Kr, et al. "Clerodendrum serratum: A clinical approach." Journal of Applied Pharmaceutical Science Issue (2012): 11-15. Poornima, B. S., Prakash L. Hegde, and A. Harini. "Pharmacological review on Clerodendrum serratum Linn. Moon." Journal of Pharmacognosy and Phytochemistry 3.5 (2015): 126-130. Ayesha, K., and Dr D. Sujana. "Evaluation of hydro alcoholic extract of Clerodendrum serratum leaf for anti-asthmatic activity." International Journal of Pharmacometrics and Integrated Biosciences 3.1 (2017): 212-219. Vidya, Anu G., et al. "Evaluation of antifungal efficacy of some medicinal plants on Candida spp. causing vulvovaginitis." (2019). |
| 8 | Antihistaminic activity | Gupta, R., Bajpai, K. G., Johri, S., & Saxena, A. M. (2007). AN OVERVIEW OF INDIAN NOVEL TRADITIONAL MEDICINAL PLANTS WITH ANTI-DIABETIC POTENTIALS. African Journal of Traditional, Complementary and Alternative Medicines, 5(1), 1–17. Retrieved from https://athmsi.org/journals/index.php/ajtcam/article/view/321. Patel, Jagruti J., Sanjeev R. Acharya, and Niyati S. Acharya. "Clerodendrum serratum (L.) Moon.–A review on traditional uses, phytochemistry and pharmacological activities." Journal of ethnopharmacology 154.2 (2014): 268-285. Taur, Dnyaneshwar J., and Ravindra Y. Patil. "Some medicinal plants with antiasthmatic potential: a current status." Asian Pacific journal of tropical biomedicine 1.5 (2011): 413-418. Gupta, S. S. "Development of antihistamine and anti-allergic activity after prolonged administration of a plant saponin from Clerodendron serratum." Journal of Pharmacy and Pharmacology 20.10 (1968): 801-802. Siva Kumar, G. M. Evaluation Changes of Lungs in Asthmatic Rats Treated with Aqueous and Non Aqueous Extract of Clerodendrum Serratum and Theophylline. Diss. Cherraan’s College of Pharmacy, Coimbatore, 2014. Somavanshi, D. B., et al. "A Comprehensive Study on Some Reported Polyherbal Formulation with Potential Antihistaminic activity." (2020). |
| 9 | Anti-asthmatic activity | Thalla, S., Tammu, J., Pentela, B., & Thalla, S. R. Antiasthmatic activity of alcoholic extract of Clerodendrum serratum induced by ovalbumin. International Journal of Chemical and Pharmaceutical Sciences, 3, 83-85,(2012). Ayesha, K., & Sujana, D. D. Evaluation of hydro alcoholic extract of Clerodendrum serratum leaf for anti-asthmatic activity. International Journal of Pharmacometrics and Integrated Biosciences, 3(1), 212-219,2017. Singh, M. K., Khare, G., Iyer, S. K., Sharwan, G., & Tripathi, D. K. Clerodendrum serratum: A clinical approach. Journal of Applied Pharmaceutical Science, (Issue), 11-15,(2012). Kumar, Praveen, and K. Nishteswar. "Phytochemical and pharmacological profiles of Clerodendrum serratum linn.(bharngi): a review." Int. J. Res. Ayurveda Pharm 4.2 (2013): 276-278. Soundalgekar, Sagar, et al. "HPTLC Fingerprinting and Anti-asthmatic Activity of Roots of Two Different Sources of Bharangi." Indian Journal of Natural Products 35.1 (2021). Bhujbal, Santosh S., et al. "Protective effects of icosahydropicenic acid isolated from the roots of clerodendrum serratum (l) moon on experimental allergic asthma." Journal of complementary and integrative medicine 7.1 (2010). |
| 10 | Immuno-modulatory activity | Juvekar, A. R., et al. "In vitro and in vivo immunomodulatory activity of aqueous extract of Clerodendrum serratum L. roots." Planta Medica 72.11 (2006): P_087. Kajaria, Divya. "†œIN-VITRO EVALUATION OF IMMUNOMODULATORY EFFECT OF POLYHERBAL COMPOUND-BHARANGYADIâ€." Journal of Drug Delivery and Therapeutics 3.1 (2013). Patel, Jagruti J., Sanjeev R. Acharya, and Niyati S. Acharya. "Clerodendrum serratum (L.) Moon.–A review on traditional uses, phytochemistry and pharmacological activities." Journal of ethnopharmacology 154.2 (2014): 268-285. |
| 11 | Wound healing activity | Kumar, Praveen, and K. Nishteswar. "Phytochemical and pharmacological profiles of Clerodendrum serratum linn.(bharngi): a review." Int. J. Res. Ayurveda Pharm 4.2 (2013): 276-278. Singh, Mukesh Kr, et al. "Clerodendrum serratum: A clinical approach." Journal of Applied Pharmaceutical Science Issue (2012): 11-15. Patel, Jagruti J., Sanjeev R. Acharya, and Niyati S. Acharya. "Clerodendrum serratum (L.) Moon.–A review on traditional uses, phytochemistry and pharmacological activities." Journal of ethnopharmacology 154.2 (2014): 268-285. Dongare, Gauri, et al. "A REVIEW ON PHYTOCHEMICAL AND PHARMACOLOGICAL ACTION OF CLERODENDRUM SERRATUM LINN.(BHARANGI)." (2020). |
| 12 | Analgesic activity | Poornima, B. S., Prakash L. Hegde, and A. Harini. "Pharmacological review on Clerodendrum serratum Linn. Moon." Journal of Pharmacognosy and Phytochemistry 3.5 (2015): 126-130. Kar, Pallab, et al. "Antioxidant and pharmaceutical potential of Clerodendrum L.: An overview." International Journal of Green Pharmacy (IJGP) 8.4 (2014). Patel, Jagruti J., Sanjeev R. Acharya, and Niyati S. Acharya. "Clerodendrum serratum (L.) Moon.–A review on traditional uses, phytochemistry and pharmacological activities." Journal of ethnopharmacology 154.2 (2014): 268-285. |
Global End Use Market
-
Available Global Market
-
Global Manufacturer Extract
-
Distribution in IORA Countries
-
Source Supply
-
Trade Name
-
Annual Consumption (in MT)
-