Coleus amboinicus Lour. Coleus amboinicus var. violaceus Gürke Coleus aromaticus Benth. Coleus carnosus Hassk. Coleus crassifolius Benth. Coleus subfrutectosus Summerh. Coleus suborbicularis Zoll. & Moritzi Coleus suganda Blanco Coleus vaalae (Forssk.) Deflers Majana amboinica (Lour.) Kuntze Majana carnosa (Hassk.) Kuntze Majana suganda (Blanco) Kuntze Ocimum vaalae Forssk.
Kingdom
Plantae
Subkingdom
Viridiplantae
Superdivision
Embryophyta
Division
Tracheophyta
Class
Magnoliopsida
Subclass
Order
Lamiales
Family
Lamiaceae
Genus
Plectranthus
Species
amboinicus
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Asthma, flu, eczema, cardiovascular disorders, bronchitis, epilepsy, Cough, flatulence, rheumatism, furuncle sprain, painful swelling, malaria, stomachaches, diarrhoea, vaginal infection, laxative and hiccup.
In Archipelago of Comoros, the roots are used against malaria 2, the leaves for their antitussive activity 3 and the decoction of the whole plant can have a triple use: sedative of the abdominal gripes, medication of the dysuria and laxative (M. Saïd Hassani, I. Zainati, S. Zrira, S. Mahdi & M. Oukessou (2012) Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Essential Oil from Archipelago of Comoros, Journal of Essential Oil-Bearing Plants, 15:4, 637-644, DOI: 10.1080/0972060X.2012.10644098) (Matthew Saive, Michel Frederich & Marie-Laure Fauconnier.
Plants used in traditional medicine in the Comoros archipelago. A review ,Portada Volume 24 (2020) Numéro 2 / 10.25518/1780-4507.18553).
| # | Country Name | Uses |
|---|---|---|
| 1 | Srilanka | In Srilanka, herb is used for whooping cough,bronchitis,pneumonia,asthma,chicken pox,cough,dysentry,liver diseases, worm infestation,renal calculi,eye diseases. |
| 2 | Malaysia | In Malaysia to treat burns and as a poultice for centipedes and scorpion bites |
| 3 | India | In India, the herb is highly useful and popular in treating respiratory disorders.It is consumed to alleviate congestion,sinusitis ,asthma,cold and sore throat |
| # | Phytochemical Constituents | PUBCHEM CID | References |
|---|---|---|---|
| 1 | δ-3-Carene | 26049 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040369 M. Saïd Hassani, I. Zainati, S. Zrira, S. Mahdi & M. Oukessou (2012) Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Essential Oil from Archipelago of Comoros, Journal of Essential Oil Bearing Plants, 15:4, 637-644, DOI: 10.1080/0972060X.2012.10644098 |
| 2 | p-Cymene | 7463 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040370 M. Saïd Hassani, I. Zainati, S. Zrira, S. Mahdi & M. Oukessou (2012) Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Essential Oil from Archipelago of Comoros, Journal of Essential Oil Bearing Plants, 15:4, 637-644, DOI: 10.1080/0972060X.2012.10644098 |
| 3 | Limonene | 22311 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040371 |
| 4 | ß-Myrcene | 31253 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040372 |
| 5 | Ocimene | 18756 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040373 |
| 6 | α-Phellandrene | 7460 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040374 |
| 7 | β-Phellandrene | 11142 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040375 |
| 8 | α-Pinene | 6654 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040376 |
| 9 | β-Pinene | 14896 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040377 |
| 10 | Sabinene | 18818 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040378 |
| 11 | α-Terpinene | 7462 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040379 |
| 12 | Ƴ-Terpinene | 7461 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040380 M. Saïd Hassani, I. Zainati, S. Zrira, S. Mahdi & M. Oukessou (2012) Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Essential Oil from Archipelago of Comoros, Journal of Essential Oil Bearing Plants, 15:4, 637-644, DOI: 10.1080/0972060X.2012.1064409 |
| 13 | α-Terpinolene | 17100 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040380 M. Saïd Hassani, I. Zainati, S. Zrira, S. Mahdi & M. Oukessou (2012) Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Essential Oil from Archipelago of Comoros, Journal of Essential Oil Bearing Plants, 15:4, 637-644, DOI: 10.1080/0972060X.2012.1064409 |
| 14 | α-Thujene | 17868 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040382 M. Saïd Hassani, I. Zainati, S. Zrira, S. Mahdi & M. Oukessou (2012) Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Essential Oil from Archipelago of Comoros, Journal of Essential Oil Bearing Plants, 15:4, 637-644, DOI: 10.1080/0972060X.2012.10644098 M. Saïd Hassani, I. Zainati, S. Zrira, S. Mahdi & M. Oukessou (2012) Chemical Composition and Antimicrobial Activity of Plectranthus amboinicus (Lour) Spring. Essential Oil from Archipelago of Comoros, Journal of Essential Oil Bearing Plants, 15:4, 637-644, DOI: 10.1080/0972060X.2012.10644098 |
| 15 | Camphor((22.2 %)) | 2537 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040383 |
| 16 | Carvacrol ((23.0 %)) | 10364 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040384 |
| 17 | Carvone | 7439 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040384 |
| 18 | 1,8-Cineole | 2758 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040384 |
| 19 | Eugenol | 3314 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040384 |
| 20 | Geraniol | 637566 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040384 |
| 21 | Linalool | 6549 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040389 |
| 22 | Geranyl acetate | 1549026 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040389 |
| 23 | Methyl eugenol | 7127 | Arumugam G, Swamy MK, Sinniah UR. Plectranthus amboinicus (Lour.) Spreng: Botanical, Phytochemical, Pharmacological and Nutritional Significance. Molecules. 2016; 21(4):369. https://doi.org/10.3390/molecules21040389 |
| # | PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES | REFERENCES |
|---|---|---|
| 1 | Antimalarial activity | Ali Mohamed Kaou, Valérie Mahiou-Leddet, Sébastien Hutter, Sidi Aïnouddine, Said Hassani, Ibrahim Yahaya, Nadine Azas, Evelyne Ollivier,Antimalarial activity of crude extracts from nine African medicinal plants,Journal of Ethnopharmacology,Volume 116, Issue 1,2008, Pages 74-83, ISSN 0378-8741,https://doi.org/10.1016/j.jep.2007.11.001. Periyanayagam K, Nirmala Devi K, Suseela L, Uma A, Ismail M. In vivo antimalarial activity of leaves of Plectranthus amboinicus (lour) spreng on Plasmodium berghei yoelii. J Commun Dis. 2008 Jun;40(2):121-5. PMID: 19301696. doi: 10.4103/0974-8490.138248. PMID: 25276063; PMCID: PMC4166814. Senthilkumar A, Venkatesalu V. Chemical composition and larvicidal activity of the essential oil of Plectranthus amboinicus (Lour.) Spreng against Anopheles stephensi: a malarial vector mosquito. Parasitol Res. 2010 Oct;107(5):1275-8. doi: 10.1007/s00436-010-1996-6. Epub 2010 Jul 29. PMID: 20668876. |
| 2 | Antimicrobial activity | Vasconcelos SECB, Melo HM, Cavalcante TTA, Júnior FEAC, de Carvalho MG, Menezes FGR, de Sousa OV, Costa RA. Plectranthus amboinicus essential oil and carvacrol bioactive against planktonic and biofilm of oxacillin- and vancomycin-resistant Staphylococcus aureus. BMC Complement Altern Med. 2017 Sep 16;17(1):462. doi: 10.1186/s12906-017-1968-9. PMID: 28915875; PMCID: PMC5602841. Shubha JR, Bhatt P. Plectranthus amboinicus leaves stimulate growth of probiotic L. plantarum: evidence for ethnobotanical use in diarrhea. J Ethnopharmacol. 2015 May 26; 166:220-7. doi: 10.1016/j.jep.2015.02.055. Epub 2015 Mar 19. PMID: 25796406. Ajitha B, Ashok Kumar Reddy Y, Sreedhara Reddy P. Biosynthesis of silver nanoparticles using Plectranthus amboinicus leaf extract and its antimicrobial activity. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Jul 15; 128:257-62. doi: 10.1016/j.saa.2014.02.105. Epub 2014 Mar 7. PMID: 24674916. Gonçalves TB, Braga MA, de Oliveira FF, Santiago GM, Carvalho CB, Brito e Cabral P, de Melo Santiago T, Sousa JS, Barros EB, do Nascimento RF, Nagao-Dias AT. Effect of subinihibitory and inhibitory concentrations of Plectranthus amboinicus (Lour.) Spreng essential oil on Klebsiella pneumoniae. Phytomedicine. 2012 Aug 15;19(11):962-8. doi: 10.1016/j.phymed.2012.05.013. Epub 2012 Jul 8. PMID: 22776104. Swamy MK, Arumugam G, Kaur R, Ghasemzadeh A, Yusoff MM, Sinniah UR. GC-MS Based Metabolite Profiling, Antioxidant and Antimicrobial Properties of Different Solvent Extracts of Malaysian Plectranthus amboinicus Leaves. Evid Based Complement Alternat Med. 2017; 2017:1517683. doi: 10.1155/2017/1517683. Epub 2017 Mar 23. PMID: 28424737; PMCID: PMC5382359. de Oliveira FF, Torres AF, Gonçalves TB, Santiago GM, de Carvalho CB, Aguiar MB, Camara LM, Rabenhorst SH, Martins AM, Valença Junior JT, Nagao-Dias AT. Efficacy of Plectranthus amboinicus (Lour.) Spreng in a Murine Model of Methicillin-Resistant Staphylococcus aureus Skin Abscesses. Evid Based Complement Alternat Med. 2013; 2013:291592. doi: 10.1155/2013/291592. Epub 2013 Feb 20. PMID: 23533472; PMCID: PMC3590755. |
| 3 | Anti-leishmanicidal activit | de Lima SC, Teixeira MJ, Lopes JE Jr, de Morais SM, Torres AF, Braga MA, Rodrigues RO, Santiago GM, Martins AC, Nagao-Dias AT. In vitro and in vivo leishmanicidal activity of Astronium fraxinifolium (Schott) and Plectranthus amboinicus (Lour.) Spreng against Leishmania (Viannia) braziliensis. Biomed Res Int. 2014;2014:848293. doi: 10.1155/2014/848293. Epub 2014 Apr 16. PMID: 24829921; PMCID: PMC4009211. |
| 4 | Anti-inflammatory activity | Chen YS, Yu HM, Shie JJ, Cheng TJ, Wu CY, Fang JM, Wong CH. Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity. Bioorg Med Chem. 2014 Mar 1;22(5):1766-72. doi: 10.1016/j.bmc.2014.01.009. Epub 2014 Jan 12. PMID: 24491635. Hsu YC, Cheng CP, Chang DM. Plectranthus amboinicus attenuates inflammatory bone erosion in mice with collagen-induced arthritis by downregulation of RANKL-induced NFATc1 expression. J Rheumatol. 2011 Sep;38(9):1844-57. doi: 10.3899/jrheum.101223. Epub 2011 Jul 1. PMID: 21724708. Gurgel AP, da Silva JG, Grangeiro AR, Oliveira DC, Lima CM, da Silva AC, Oliveira RA, Souza IA. In vivo study of the anti-inflammatory and antitumor activities of leaves from Plectranthus amboinicus (Lour.) Spreng (Lamiaceae). J Ethnopharmacol. 2009 Sep 7;125(2):361-3. doi: 10.1016/j.jep.2009.07.006. Epub 2009 Jul 14. PMID: 19607901. Ravikumar VR, Dhanamani M, Sudhamani T. In-vitro anti- inflammatory activity of aqueous extract of leaves of Plectranthus amboinicus (Lour.) Spreng. Anc Sci Life. 2009 Apr;28(4):7-9. PMID: 22557324; PMCID: PMC3336327. |
| 5 | Antidiabetic activity | Koti BC, Gore A, Thippeswamy AH, Swamy AH, Kulkarni R. Alcoholic leaf extract of Plectranthus amboinicus regulates carbohydrate metabolism in alloxan-induced diabetic rats. Indian J Pharmacol. 2011 May;43(3):286-90. doi: 10.4103/0253-7613.81520. PMID: 21713092; PMCID: PMC3113380. |
| 6 | Antineoplastic activity | Gurgel AP, da Silva JG, Grangeiro AR, Oliveira DC, Lima CM, da Silva AC, Oliveira RA, Souza IA. In vivo study of the anti-inflammatory and antitumor activities of leaves from Plectranthus amboinicus (Lour.) Spreng (Lamiaceae). J Ethnopharmacol. 2009 Sep 7;125(2):361-3. doi: 10.1016/j.jep.2009.07.006. Epub 2009 Jul 14. PMID: 19607901. Manjamalai A, Grace VM. The chemotherapeutic effect of essential oil of Plectranthus amboinicus (Lour) on lung metastasis developed by B16F-10 cell line in C57BL/6 mice. Cancer Invest. 2013 Jan;31(1):74-82. doi: 10.3109/07357907.2012.749268. Epub 2012 Dec 18. PMID: 23249189. Yulianto W, Andarwulan N, Giriwono PE, Pamungkas J. HPLC-based metabolomics to identify cytotoxic compounds from Plectranthus amboinicus (Lour.) Spreng against human breast cancer MCF-7Cells. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Dec 15;1039:28-34. doi: 10.1016/j.jchromb.2016.10.024. Epub 2016 Oct 22. PMID: 27816313. |
| 7 | Diuretic activity | Patel R, Mahobia NK, Gendle R, Kaushik B, Singh SK. Diuretic activity of leaves of Plectranthus amboinicus (Lour) Spreng in male albino rats. Pharmacognosy Res. 2010 Mar;2(2):86-8. doi: 10.4103/0974-8490.62956. PMID: 21808546; PMCID: PMC3140112. |
| 8 | Analgesic activity | Chiu YJ, Huang TH, Chiu CS, Lu TC, Chen YW, Peng WH, Chen CY. Analgesic and Antiinflammatory Activities of the Aqueous Extract from Plectranthus amboinicus (Lour.) Spreng. Both In Vitro and In Vivo. Evid Based Complement Alternat Med. 2012;2012:508137. doi: 10.1155/2012/508137. Epub 2011 Sep 11. PMID: 21915187; PMCID: PMC3170901. |
| 9 | Rheumatoid arthritis | Chang JM, Cheng CM, Hung LM, Chung YS, Wu RY. Potential Use of Plectranthus amboinicus in the Treatment of Rheumatoid Arthritis. Evid Based Complement Alternat Med. 2010 Mar;7(1):115-20. doi: 10.1093/ecam/nem168. Epub 2007 Nov 23. PMID: 18955284; PMCID: PMC2816374. Hsu YC, Cheng CP, Chang DM. Plectranthus amboinicus attenuates inflammatory bone erosion in mice with collagen-induced arthritis by downregulation of RANKL-induced NFATc1 expression. J Rheumatol. 2011 Sep;38(9):1844-57. doi: 10.3899/jrheum.101223. Epub 2011 Jul 1. PMID: 21724708. |
| 10 | Nephroprotective | Palani S, Raja S, Naresh R, Kumar BS. Evaluation of nephroprotective, diuretic, and antioxidant activities of plectranthus amboinicus on acetaminophen-induced nephrotoxic rats. Toxicol Mech Methods. 2010 May;20(4):213-21. doi: 10.3109/15376511003736787. PMID: 20367443. |
| # | AVALAIBLE PRODUCTS | MANUFACTURERS AND SUPPLIERS | URL |
|---|---|---|---|
| 1 | KILLI Karpooravalli | KILLI farm made | Open Url |
| 2 | Neotea Karpooravalli Coleus Amboinicus Powder | Neotea | Open Url |
Global End Use Market
pharmaceutical Traditional/folklore
Available Global Market
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Global Manufacturer Extract
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Distribution in IORA Countries
Comoros Kenya Madagascar Mozambique Seychelles South Africa Tanzania Bangladesh India Indonesia Sri Lanka Thailand Yemen Australia Mauritius.
Source Supply
Tropical regions of the world, woodland, near coastals , and roadsides
Trade Name
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Annual Consumption (in MT)
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| # | PATENT TITLE | PATENT/APPLICATION NO. | PATENT OFFICE | SOURCE |
|---|---|---|---|---|
| 1 | Multifunctional healthcare soap and manufacturing method thereof | CN110205212 (A) | -- | Details |
| 2 | IMMUNOLOGICAL ENHANCER | JPS6259218 (A) | -- | Details |
| 3 | MODIFIED NUTRACEUTICAL COMPOSITION | WO2005094854 (A1) | -- | Details |