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Berberis aristata DC
BOTANICAL DETAILS OF PLANT
Synonyms
Berberis bussmul K.Koch ex Miq. Berberis coccinea K.Koch Berberis gracillima K.Koch ex Miq. Berberis macrophylla K.Koch Berberis serratifolia K.Koch Berberis coerulescens G.Nicholson Berberis elegans K.Koch Berberis gracilis Lindl. Berberis umbellata Lindl. Berberis undulata K.Koch
Kew Herbarium Links
Classification
Kingdom
Plantae
Subkingdom
Tracheophyta
Superdivision
--
Division
--
Class
Magnoliopsida
Subclass
Order
Ranunculales
Family
Barberidaceae
Genus
Barberis L
Species
--
Plant Description
Shrub, 3-4 m tall; stem terete, glabrous, pale yellow, obscurely or very
minutely verruculose; internodes 2.5-4.5 cm long; spines mostly simple, rarely
3-fid, 5-10 mm long. Leaves obovate-elliptic, 3 - 6 (-7.5) cm long, 1-2.5 (-3)
cm broad, subsessile to very shortly petioled, usually 4-8 spinose-dentate at
margin, pale, slightly reticulately veined. Racemes 2-4 cm long,
15-25-flowered, rigid, rarely slightly compound. Flowers 10-12 mm across, pale
yellow with petals slightly larger than the inner sepals; pedicels 5-10 mm long
in fruit, stout. Prophylls c. 1 mm long. Outer sepals c. 2 mm long, ovate;
middle ones c. twice and the inner sepals c. thrice as long, obovate. Petals c.
7 mm long, 4.5 mm broad, obovate with retuse apices and somewhat clawed base with
a pair of marginal glands. Stamens c. 5.5 mm long with subapiculate apices.
Berries oblong-globose, 7-9 mm long, 6-7 mm broad, black, pruinose-white; style
1 mm long; seeds 3-4, oblong-ellipsoid, 3-4 mm long.
Habit/Life Form
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DISTRIBUTION OF SPECIES IN INDIA
Jammu & Kashmir, Himachal Pradesh, Tamil Nadu, Sikkim, Uttarakhand and Bangalore.
AGROCLIMATIC CONDITIONS
| # | Soil and Climate | Temperature (°C) | Average Annual Rainfall (mm) |
|---|---|---|---|
| 1 | The plant is self-fertile. Suitable for: light (sandy), medium (loamy) and heavy (clay) soils and can grow in heavy clay and nutritionally poor soils. | 1- 36 | 1100 - 1400 |
Local Names
| # | Language Name | Local Name |
|---|---|---|
| 1 | -- | -- |
International Local Names
| # | Country Name | Local Name |
|---|---|---|
| 1 | -- | -- |
Plant Parts Used
Root, stem and leaves
System of Medicine
Ayurveda, Siddha, Unani and Homoeopathy
Intended Use
Antibacterial, antiperiodic, antidiarrheal and anticancer and it is also used in the treatment of ophthalmic infection. It is used as a tonic, alternative, demulcent, diaphoretic, and diuretic, jaundice, skin diseases and syphilis.
Traditional Application
Uses in IORA Countries
| # | Country Name | Uses |
|---|---|---|
| 1 | -- | -- |
Phytochemical Details
| # | Phytochemical Constituents | PUBCHEM CID | References |
|---|---|---|---|
| 1 | Barberine | - | |
| 2 | Oxyberberine | - | |
| 3 | Berbamine | - | |
| 4 | Aromoline | - | |
| 5 | Palmatine | - | |
| 6 | Oxyacanthine | - | |
| 7 | Taxilamine | - | |
| 8 | Epiberberine | - | |
| 9 | Palmatine | - | |
| 10 | Dehydrocaroline | - | |
| 11 | Jatrorhizine | - | |
| 12 | Columbamine | - | |
| 13 | Dihyrokarachine | - | |
| 14 | Taximaline | - | |
| 15 | 1-O methyl pakistanine | - | |
| 16 | Pseudopalmatine chloride | - | |
| 17 | Pseudoberberine chloride | - |
Pharmacological Details
| # | PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES | REFERENCES |
|---|---|---|
| 1 | Anti-hepatotoxic | Potdar D, Hirwani RR, Dhulap S. Phyto-chemical and pharmacological applications of Berberis aristata. Fitoterapia. 2012 Jul;83(5):817-30. doi: 10.1016/j.fitote.2012.04.012. PMID: 22808523. Dehar, N., R. Walia, R. Verma, and P. Pandey. “HEPATOPROTECTIVE ACTIVITY OF BERBERISARISTATA ROOT EXTRACT AGAINST CHEMICAL INDUCED ACUTE HEPATOTOXICITY IN RATS”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 6, no. 9, Nov. 2013, pp. 53-56, https://innovareacademics.info/journals/index.php/ajpcr/article/view/535.
Gilani, A.-U.H. and Janbaz, K.H. (1995), Preventive and curative effects
of Berberis aristata Fruit extract on paracetamol- and CCl4-induced
hepatotoxicity. Phytother. Res., 9: 489-494.
https://doi.org/10.1002/ptr.2650090705.
Feng, Y., Siu, KY., Ye, X. et al. Hepatoprotective effects of berberine
on carbon tetrachloride-induced acute hepatotoxicity in rats. Chin Med 5, 33
(2010). https://doi.org/10.1186/1749-8546-5-33. Tsai PL, Tsai TH. Hepatobiliary excretion of berberine. Drug Metab
Dispos. 2004 Apr;32(4):405-12. doi: 10.1124/dmd.32.4.405. PMID: 15039293.
Janbaz KH, Gilani AH. Studies on preventive and curative effects of
berberine on chemical-induced hepatotoxicity in rodents. Fitoterapia. 2000
Feb;71(1):25-33. doi: 10.1016/s0367-326x(99)00098-2. PMID: 11449466. |
| 2 | Anti-pyretic | Potdar D, Hirwani RR, Dhulap S. Phyto-chemical and pharmacological
applications of Berberis aristata. Fitoterapia. 2012 Jul;83(5):817-30. doi:
10.1016/j.fitote.2012.04.012. PMID: 22808523.
Gilani AH, Janbaz KH. Prevention of acetaminophen-induced liver damage
by Berberis aristata leaves. Biochem Soc Trans. 1992 Nov;20(4):347S. doi:
10.1042/bst020347s. PMID: 1487011. |
| 3 | Anticancer activity | Pai KS, Srilatha P, Suryakant K, Setty MM, Nayak PG, Rao CM, Baliga MS.
Anticancer activity of Berberis aristata in Ehrlich ascites carcinoma-bearing
mice: a preliminary study. Pharm Biol. 2012 Mar;50(3):270-7. doi:
10.3109/13880209.2011.599035.
Epub 2011 Nov 15. PMID: 22085276. Potdar D, Hirwani RR, Dhulap S.
Phyto-chemical and pharmacological applications of Berberis aristata.
Fitoterapia. 2012 Jul;83(5):817-30. doi: 10.1016/j.fitote.2012.04.012. PMID:
22808523.
Samadi P, Sarvarian P, Gholipour
E, Asenjan KS, Aghebati-Maleki L, Motavalli R, Hojjat-Farsangi M, Yousefi M.
Berberine: A novel therapeutic strategy for cancer. IUBMB Life. 2020
Oct;72(10):2065-2079. doi: 10.1002/iub.2350. Epub 2020 Jul 31. PMID:
32735398.
Balakrishna A, Kumar MH.
Evaluation of Synergetic Anticancer Activity of Berberine and Curcumin on
Different Models of A549, Hep-G2, MCF-7, Jurkat, and K562 Cell Lines. Biomed
Res Int. 2015; 2015:354614. doi: 10.1155/2015/354614. Epub 2015 Jun 29. PMID:
26247019; PMCID: PMC4499639.
Sengupta P, Raman S, Chowdhury R,
Lohitesh K, Saini H, Mukherjee S, Paul A. Evaluation of Apoptosis and Autophagy
Inducing Potential of Berberis aristata, Azadirachta indica, and Their
Synergistic Combinations in Parental and Resistant Human Osteosarcoma Cells.
Front Oncol. 2017 Dec 11;7:296. doi: 10.3389/fonc.2017.00296. PMID: 29312880;
PMCID: PMC5732233. |
| 4 | Antiplasmodial activity | Chandel S, Bagai U, Semwal RB, Semwal DK. Antiplasmodial activity of
aqueous extract of Berberis aristata roots against Plasmodium berghei-infected
BALB/c mice. Pharm Biol. 2015;53(12):1735-40. doi:
10.3109/13880209.2015.1005750. Epub 2015 Apr 10. PMID: 25858288. |
| 5 | Anti-osteoporotic activity | Yogesh HS, Chandrashekhar VM, Katti HR, Ganapaty S, Raghavendra HL,
Gowda GK, Goplakhrishna B. Anti-osteoporotic activity of aqueous-methanol
extract of Berberis aristata in ovariectomized rats. J Ethnopharmacol. 2011 Mar
24;134(2):334-8. doi: 10.1016/j.jep.2010.12.013. Epub 2010 Dec 21. PMID:
21182919. |
| 6 | Anti-inflammatory activity | Gupta SK, Agarwal R, Srivastava S, Agarwal P, Agrawal SS, Saxena R,
Galpalli N. The anti-inflammatory effects of Curcuma longa and Berberis
aristata in endotoxin-induced uveitis in rabbits. Invest Ophthalmol Vis Sci.
2008 Sep;49(9):4036-40. doi: 10.1167/iovs.07-1186. Epub 2008 Apr 17. PMID:
18421073.
Nimisha, Rizvi DA, Fatima Z, Neema, Kaur CD. Antipsoriatic and Anti-inflammatory Studies of Berberis aristata Extract Loaded Nanovesicular Gels. Pharmacogn Mag. 2017 Oct;13(Suppl 3): S587-S594. doi: 10.4103/pm.pm_210_17. Epub 2017 Sep 8. PMID: 29142419; PMCID: PMC5669102. |
| 7 | Antipsoriatic activity | Nimisha, Rizvi DA, Fatima Z, Neema, Kaur CD. Antipsoriatic and
Anti-inflammatory Studies of Berberis aristata Extract Loaded Nanovesicular
Gels. Pharmacogn Mag. 2017 Oct;13(Suppl 3): S587-S594. doi:
10.4103/pm.pm_210_17. Epub 2017 Sep 8. PMID: 29142419; PMCID: PMC5669102. |
| 8 | Antidiarrheal activity | Joshi PV, Shirkhedkar AA, Prakash K, Maheshwari VL. Antidiarrheal
activity, chemical and toxicity profile of Berberis aristata. Pharm Biol. 2011
Jan;49(1):94-100. doi: 10.3109/13880209.2010.500295. Epub 2010 Aug 25. PMID:
20738174.
Samadi P, Sarvarian P, Gholipour E, Asenjan KS, Aghebati-Maleki L,
Motavalli R, Hojjat-Farsangi M, Yousefi M. Berberine: A novel therapeutic
strategy for cancer. IUBMB Life. 2020 Oct;72(10):2065-2079. doi:
10.1002/iub.2350. Epub 2020 Jul 31. PMID: 32735398.
Ashrafizadeh M, Fekri HS, Ahmadi Z, Farkhondeh T, Samarghandian S.
Therapeutic and biological activities of berberine: The involvement of Nrf2
signaling pathway. J Cell Biochem. 2020 Feb;121(2):1575-1585. doi:
10.1002/jcb.29392. Epub 2019 Oct 14. PMID: 31609017. |
| 9 | Antiproliferative activity | Sood H, Kumar Y, Gupta VK, Arora DS. Scientific validation of the
antimicrobial and antiproliferative potential of Berberis aristata DC root
bark, its phytoconstituents and their biosafety. AMB Express. 2019 Sep
11;9(1):143. doi: 10.1186/s13568-019-0868-4. PMID: 31512002; PMCID: PMC6738363. |
| 10 | Antihyperglycemic activity | Singh J, Kakkar P. Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. J Ethnopharmacol. 2009 May 4;123(1):22-6. doi: 10.1016/j.jep.2009.02.038. Epub 2009 Mar 5. PMID: 19429334. Derosa G, Bonaventura A, Bianchi L, Romano D, D'Angelo A, Fogari E, Maffioli P. Berberis aristata/Silybum marianum fixed combination on lipid profile and insulin secretion in dyslipidemic patients. Expert Opin Biol Ther. 2013 Nov;13(11):1495-506. doi: 10.1517/14712598.2013.832751. Epub 2013 Aug 24. PMID: 23971720 . Rathor L, Pant A, Awasthi H, Mani D, Pandey R. An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology. 2017 Feb;18(1):131-147. doi: 10.1007/s10522-016-9668-2. Epub 2016 Nov 16. PMID: 27853905.
Di Pierro F, Putignano P, Villanova N, Montesi L, Moscatiello S, Marchesini G. Preliminary study about the possible glycemic clinical advantage in using a fixed combination of Berberis aristata and Silybum marianum standardized extracts versus only Berberis aristata in patients with type 2 diabetes. Clin Pharmacol. 2013 Nov 19; 5:167-74. doi: 10.2147/CPAA.S54308. PMID: 24277991; PMCID: PMC3838471. Chatuphonprasert W, Nemoto N, Sakuma T, Jarukamjorn K. Modulations of cytochrome P450 expression in diabetic mice by berberine. Chem Biol Interact. 2012 Mar 5;196(1-2):23-9. doi: 10.1016/j.cbi.2012.01.006. Epub 2012 Feb 8. PMID: 22342832. Guarino G, Strollo F, Carbone L, Della Corte T, Letizia M, Marino G,
Gentile S. Bioimpedance analysis, metabolic effects and safety of the
association Berberis aristata/Bilybum marianum: a 52-week double-blind,
placebo-controlled study in obese patients with type 2 diabetes. J Biol Regul
Homeost Agents. 2017 Apr-Jun;31(2):495-502. PMID: 28685558.
|
| 11 | Anti-lipidemic | Potdar D, Hirwani RR, Dhulap S. Phyto-chemical and pharmacological applications of Berberis aristata. Fitoterapia. 2012 Jul;83(5):817-30. doi: 10.1016/j.fitote.2012.04.012. PMID: 22808523.
Razzaq, Faiza & Khan, Rafeeq & Feroz, Zeeshan & Afroz, Syeda. (2011). Effect of Berberis aristata on lipid profile and coagulation parameters. African journal of pharmacy and pharmacology. 5. 943-947.
Akbar S. (2020) Berberis aristata DC. (Berberidaceae). In: Handbook of 200 Medicinal Plants. Springer, Cham. https://doi.org/10.1007/978-3-030-16807-0_43.
Faiza Abdul Razzaq, Rafeeq Alam Khan Zeeshan Feroz and Syeda Afroz, Effect of Berberis aristata on lipid profile and coagulation parameters, African Journal of Pharmacy and Pharmacology Vol. 5(7), pp.
943-947, July 2011 Available online http://www.academicjournals.org/ajpp DOI: 10.5897/AJPP10.322. |
| 12 | Gynaecological disorders | Potdar D, Hirwani RR, Dhulap S. Phyto-chemical and pharmacological applications of Berberis aristata. Fitoterapia. 2012 Jul;83(5):817-30. doi: 10.1016/j.fitote.2012.04.012. PMID: 22808523. Soffar SA, Metwali DM, Abdel-Aziz
SS, el-Wakil HS, Saad GA. Evaluation of the effect of a plant alkaloid
(berberine derived from Berberis aristata) on Trichomonas vaginalis in vitro. J
Egypt Soc Parasitol. 2001 Dec;31(3):893-904 + 1p plate. PMID: 11775115. |
| 13 | Haemorrhoids | Potdar D, Hirwani RR, Dhulap S. Phyto-chemical and pharmacological
applications of Berberis aristata. Fitoterapia. 2012 Jul;83(5):817-30. doi:
10.1016/j.fitote.2012.04.012. PMID:
22808523.
Khan MI, Rahman MA, Khalid M, Khushtar M, Mujahid M. Quality Control
Standardization and Evaluation of Antimicrobial Potential of Daruhaldi
(Berberis aristata DC) Stem Bark. J Diet Suppl. 2020;17(1):97-109. doi:
10.1080/19390211.2018.1484405. Epub 2018 Oct 5. PMID: 30289011. Prakash Paranjpe, Pralhad Patki,
Nishikant Joshi,Efficacy of an indigenous formulation in patients with bleeding
piles: a preliminary clinical study, Fitoterapia, Volume 71, Issue 1, 2000,
Pages 41-45, ISSN 0367-326X, https://doi.org/10.1016/S0367-326X(99)00115-X. Akbar S. (2020) Berberis aristata
DC. (Berberidaceae). In: Handbook of 200 Medicinal Plants. Springer, Cham. https://doi.org/10.1007/978-3-030-16807-0_43.
Thakur, Pallavi, Chawla, Raman, Narula, Alka, Goel, Rajeev, Arora, Rajesh and Sharma, Rakesh Kumar. "In vitro bactericidal activity of Berberis aristata extract against clinical isolates of carbapenem-resistant Escherichia coli" Journal of Complementary and Integrative Medicine, vol. 13, no. 3, 2016, pp. 229-237. https://doi.org/10.1515/jcim-2015-0066 |
| 14 | Cardiotonic | Gilani AH, Janbaz KH, Aziz N, Herzig MJ, Kazmi MM, Choudhary MI, Herzig JW. Possible mechanism of selective inotropic activity of the n-butanolic fraction from Berberis aristata fruit. Gen Pharmacol. 1999 Nov;33(5):407-14. doi: 10.1016/s0306-3623(99)00035-x. PMID: 10553882.
Akbar S. (2020) Berberis aristata DC. (Berberidaceae). In: Handbook of 200 Medicinal Plants. Springer, Cham. https://doi.org/10.1007/978-3-030-16807-0_43. Shailja Choudhary, Hemlata Kaurav, Madhusudan S., & Gitika Chaudhary. (2021). Daruharidra (Berberis aristata): Review based upon its Ayurvedic Properties. International Journal for Research in Applied Sciences and Biotechnology, 8(2), 98-106. https://doi.org/10.31033/ijrasb.8.2.12. Rajarshi Biswas, Pulok K. Mukherjee & Sushil K. Chaudhary (2016) Tyrosinase
inhibition kinetic studies of standardized extract of Berberis aristata,
Natural Product Research, 30:12, 1451-1454, DOI: 10.1080/14786419.2015.1062376. |
| 15 | Anti PAF activity | Tripathi, Y.B. and Shukla, S.D. (1996), Berberis aristata Inhibits PAF Induced Aggregation of Rabbit Platelets. Phytother. Res., 10: 628-630. https://doi.org/10.1002/(SICI)1099-1573(199611)10:7<628: AID-PTR913>3.0.CO;2-X. Komal, Sharma & Ranjan, Bairwa & Neelam, Chauhan & Birendra, Shrivastava & Saini, Neeraj. (2011). Berberis aristata: A Review. International Journal of Research in Ayurveda & Pharmacy. 2. |
| 16 | Antimicrobial activity | Sood, H., Kumar, Y., Gupta, V.K. et al. Scientific validation of the antimicrobial and antiproliferative potential of Berberis aristata DC root bark, its phytoconstituents and their biosafety. AMB Expr 9, 143 (2019). https://doi.org/10.1186/s13568-019-0868-4.
Mohammad Irfan Khan, Md. Azizur Rahman, Badruddeen, Mohammad Khalid, Mohammad Khushtar & Md. Mujahid (2020) Quality Control Standardization and Evaluation of Antimicrobial Potential of Daruhaldi (Berberis aristata DC) Stem Bark, Journal of Dietary Supplements, 17:1, 97-109, DOI: 10.1080/19390211.2018.1484405.
Joshi PV, Shirkhedkar AA, Prakash K, Maheshwari VL. Antidiarrheal activity, chemical and toxicity profile of Berberis aristata. Pharm Biol. 2011 Jan;49(1):94-100. doi: 10.3109/13880209.2010.500295. Epub 2010 Aug 25. PMID: 20738174.
Chandra H, Patel D, Kumari P, Jangwan JS, Yadav S. Phyto-mediated synthesis of zinc oxide nanoparticles of Berberis aristata: Characterization, antioxidant activity and antibacterial activity with special reference to urinary tract pathogens. Mater Sci Eng C Mater Biol Appl. 2019 Sep; 102:212-220. doi: 10.1016/j.msec.2019.04.035. Epub 2019 Apr 13. PMID: 31146992.
Thakur P, Chawla R, Goel R, Narula A, Arora R, Sharma RK. Augmenting the potency of third-line antibiotics with Berberis aristata: In vitro synergistic activity against carbapenem-resistant Escherichia coli. J Glob Antimicrob Resist. 2016 Sep;6:10-16. doi: 10.1016/j.jgar.2016.01.015. Epub 2016 Mar 29. PMID: 27530832.
Chandel S, Bagai U, Semwal RB, Semwal DK. Antiplasmodial activity of aqueous extract of Berberis aristata roots against Plasmodium berghei-infected BALB/c mice. Pharm Biol. 2015;53(12):1735-40. doi: 10.3109/13880209.2015.1005750. Epub 2015 Apr 10. PMID: 25858288.
Thakur, Monika; Sharma, Kunjan; Mehta, Sonia; Rai, Swati; Sharma, Isha; et al.Research Journal of Pharmacy and Technology; Raipur Vol. 13, Iss. 12, (Dec 2020): 5763-5767. DOI:10.5958/0974-360X.2020.01004.5.
S. TAMILSELVI, PADMA VENKATASUBRAMANIAN, K.P. KANNAN AND N.S. VASANTHI, STUDIES ON ESTIMATION OF BERBERINE AND ANTIMICROBIAL ACTIVITY OF DIFFERENT EXTRACTS OF BERBERIS ARISTATA DC.,Asian Jr. of Microbiol. Biotech. Env. Sc. Vol. 16, No. (3): 2014: 669-672.
SEEMA SAXENA, REENU NEGI AND SAURABH GULERI,Antimicrobial potential of Berberis aristata DC. against some human bacterial pathogens,J. Mycopathol. Res. 52(2): 227-235, 2014; (ISSN 0971-3719).
Potdar D, Hirwani RR, Dhulap S. Phyto-chemical and pharmacological applications of Berberis aristata. Fitoterapia. 2012 Jul;83(5):817-30. doi: 10.1016/j.fitote.2012.04.012. PMID: 22808523.
Singh M, Srivastava S, Rawat AK. Antimicrobial activities of Indian Berberis species. Fitoterapia. 2007 Dec;78(7-8):574-6. doi: 10.1016/j.fitote.2007.03.021. Epub 2007 May 24. PMID: 17583443.
Soffar SA, Metwali DM, Abdel-Aziz SS, el-Wakil HS, Saad GA. Evaluation of the effect of a plant alkaloid (berberine derived from Berberis aristata) on Trichomonas vaginalis in vitro. J Egypt Soc Parasitol. 2001 Dec;31(3):893-904 + 1p plate. PMID: 11775115.
Sharma RS, Mishra V, Singh R, Seth N, Babu CR. Antifungal activity of some Himalayan medicinal plants and cultivated ornamental species. Fitoterapia. 2008 Dec;79(7-8):589-91. doi: 10.1016/j.fitote.2008.06.004. Epub 2008 Jul 11. PMID: 18672040.
Ghosh AK, Bhattacharyya FK, Ghosh DK. Leishmania donovani: amastigote inhibition and mode of action of berberine. Exp Parasitol. 1985 Dec;60(3):404-13. doi: 10.1016/0014-4894(85)90047-5. PMID: 4076392.
Sohni YR, Kaimal P, Bhatt RM. The antiamoebic effect of a crude drug formulation of herbal extracts against Entamoeba histolytica in vitro and in vivo. J Ethnopharmacol. 1995 Jan;45(1):43-52. doi: 10.1016/0378-8741(94)01194-5. PMID: 7739226. |
| 17 | Anti-osteoporotic activity | Yogesh HS, Chandrashekhar VM, Katti HR, Ganapathy S, Raghavendra HL, Gowda GK, Gopalkrishna B. Anti-osteoporotic activity of aqueous-methanol extract of Berberis aristata in ovariectomized rats. J Ethnopharmacology. 2011 Mar 24;134(2):334-8. doi: 10.1016/j.jep.2010.12.013. Epub 2010 Dec 21. PMID: 21182919. Kumar R, Nair V, Gupta YK, Singh S, Arunraja S. Berberis aristata Ameliorates Adjuvant-Induced Arthritis by Inhibition of NF-κB and Activating Nuclear Factor-E2-related Factor 2/hem Oxygenase (HO)-1 Signaling Pathway. Immunol Invest. 2016 Aug;45(6):473-89. doi: 10.3109/08820139.2016.1172638. Epub 2016 Jun 13. PMID: 27294302. Kumar R, Gupta YK, Singh S. Anti-inflammatory and anti-granuloma activity of Berberis aristata DC. in experimental models of inflammation. Indian J Pharmacol. 2016 Mar-Apr;48(2):155-61. doi: 10.4103/0253-7613.178831. PMID: 27114638; PMCID: PMC4825432. |
Market Overview
Global End Use Market
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Available Global Market
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Global Manufacturer Extract
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Distribution in IORA Countries
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Trade Data
Source Supply
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Trade Name
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Annual Consumption (in MT)
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Adulterant/Substitute
CULTIVARS AND VARIETIES
Berberis aristata var. aristata, Berberis aristata var. floribunda (G.Don) Hook.fil. & Thomson and Berberis aristata var. micrantha Hook.fil. & Thomson