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Coscinium fenestratum (Goetgh.) Colebr.
BOTANICAL DETAILS OF PLANT
Synonyms
Coscinium maingayi ,Pierre Coscinium wightianum ,Miers ex Diels Coscinium usitatum Pierre Coscinium wallichianum Miers Coscinium peltatum Merr.Coscinium miosepalum Diels
Kew Herbarium Links
Classification
Kingdom
Plantae
Subkingdom
-
Superdivision
-
Division
-
Class
Magnoliopsida
Subclass
-
Order
Ranunculales
Family
Menispermaceae
Genus
Coscinium Colebr.
Species
Coscinium fenestratum (Gaertn.) Colebr.
Plant Description
Large climbers, wood, and sap yellow in color. Branchlets terete, ridged or smooth, brownish tomentose at first, later glabrescent, becoming whitish, presence of disciform petiole-scars. Leaves simple, alternate, 15-25x 8-20 cm,subpeltate, leaf blade broadly ovate, acuminate at apex, base cordate, glabrous above, white below; petioles 2-15 cm long. Inflorescence on long peduncles, of 5-11 cm long racemes, 6-7 mm across, Flowers yellow, small, unisexual in supra axillary inflorescence. Fruits globose drupes, smooth contains one globose seed.
Habit/Life Form
Woody climber
DISTRIBUTION OF SPECIES IN INDIA
Western Ghats of Karnataka, Kerala, and Tamil Nadu up to an altitude of 1000 m MSL.
AGROCLIMATIC CONDITIONS
| # | Soil and Climate | Temperature (°C) | Average Annual Rainfall (mm) |
|---|---|---|---|
| 1 | Prefers humidity and shade in association with many shrubs and large trees. pH - 5.2 | 15-25 | 2000- 3671 |
Local Names
| # | Language Name | Local Name |
|---|---|---|
| 1 | English | False calumba root |
| 2 | Hindi | Jhar-haldi, Jhar-i-haldi |
| 3 | Kannada | Arasina ballii, Dodda Maradarishna, Maradaarasina |
| 4 | Malayalam | Haridram, Maramannal, Mara |
| 5 | Marathi | Bhadi halad, Jhade-halade, Venivel |
| 6 | Sanskrit | Canda, Daru-haridrakam, daruharidra, pitachandanam |
| 7 | Tamil | Alakanirani, aravam, arruram, katoriyam, maramanjal |
| 8 | Telugu | Manipasupoo |
| 9 | Tibetan | Tsan dan ser pa |
International Local Names
| # | Country Name | Local Name |
|---|---|---|
| 1 | Indonesia | Akar kuning (Java), akar kunyit (Bangka), upak-upak (East Kalimantan) |
| 2 | Borneo | Ambuksigubang(Bru.) |
| 3 | Malaysia | Kunyit-kunyit babi (Peninsular), abang asuh (Sabah), perawan (Sarawak), Babas Lingungan |
| 4 | Thailand | Khruea hen (north-eastern), khamin khruea (south-eastern) |
| 5 | Vietnam | Vàng d?ng, hoàng d?ng, d?ng giang. |
| 6 | Cambodia | Vang dang |
| 7 | Malaya | Akar kuning, kunyit-kunyit, kunyit-kunyit babi, tol, kupak, kopak |
Plant Parts Used
Stem, bark, root, fruit
System of Medicine
-
Intended Use
Indigestion, flatulence, liver disorders, fever, dressing wounds, ulcers, snake-bites, abdominal disorders, jaundice, diabetes, bleeding piles, cough, diabetes, diarrhea, dyspepsia, Excessive menstruation, Fever, hemorrhage, Tetanus, as alternate to quinine in treating Malaria
Traditional Application
1- Kani traditional healers residing in the hodu hills of Kerala use the herb to treat Jaundice, diabetes Headache, Endocrinal disorders (ED) Coscinium fenestratum (Thangaraj Francis Xavier, Moorthy Kannan, Leyone Lija, Anthonysamy Auxillia, Antony Kanthi Freeda Rose, Subburaman Senthil kumar, Ethnobotanical study of Kani tribes in Thoduhills of Kerala, South India, Journal of Ethnopharmacology, Volume 152, Issue 1, 2014, Pages 78-90, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2013.12.016.)
2- C. fenestratum is traditionally used for treating tetanus.
3- The stem is considered for skin diseases, abdominal disorders, jaundice, and general debility. It is also beneficial in curing dyspepsia and as a febrifuge (Punitha IS, Rajendran K, Shirwaikar A, Shirwaikar A., Alcoholic stem extract of Coscinium fenestratum regulates carbohydrate metabolism and improves antioxidant status in streptozotocin-nicotinamide induced diabetic rats., Evid Based Complement Alternat Med. 2005 Sep;2(3):375-81.).
4- It can cure several common ailments like -influenza and eye diseases, bleeding piles and excessive bleeding during menstruation. The bark has the potential to cure leucorrhea and other gynecological problems (Danapur V, Haleshi C, Sringeswara AN. Endangered Medicinal Plant Coscinium fenestratum (Gaertn.) Colebr. - A Review. Pharmacogn J. 2020;12(5):1077-85).
5- The traditional practitioners of various districts of Karnataka uses Coscinium fenastratum for treating - pimples, psoriasis, itching, eczema, wound, Crack heel, obstruction in the urinary tract, diabetes, joint pain (D. Roopa and B.B. Hosetti,Medicinal uses of Coscinium fenestratum in Local Health Traditions of Karnataka, India. ,Asia Pacific Journal of Research www.apjor.com Vol: I. Issue LVIII, December 2017).
6- This plant is used by traditional healers for treating herpes in coastal Karnataka, India. The extract of the stem is useful in snake bites. The stem bark is used for treating intermittent fevers. (Rai, R.V., Rajesh, P.S. & Kim, HM. Medicinal use of Coscinium fenestratum (Gaertn.) Colebr.: a short review. Orient Pharm Exp Med 13, 1–9 (2013). https://doi.org/10.1007/s13596-012-0094-y).
Uses in IORA Countries
| # | Country Name | Uses |
|---|---|---|
| 1 | Malaysia | 1- In Peninsular Malaysia, roots of C. fenestratum are used for dressing wound, burns, fever and for ulcer. 2- The Murut population are indigenous groups living in Sabah (located in the northernmost part of Borneo) Malaysia uses the herb to cure thinning and yellowing skin.For this entire plant is boiled in water to make a tea(Julius Kulip, An ethnobotanical survey of medicinal and other useful plants of Muruts in Sabah, Malaysia,Telopea 10(1): 2003 |
| 2 | Sri Lanka | The decoction of the bark is used to cure malarial fever,inflammation, ulcers, skin disease, abdominal disorders, jaundice, and general debility. The root paste is claimed to have antiseptic properties and used to dress bruises, wounds and contusions. |
| 3 | Thailand | In Northeastern part of country, Coscinium fenestratum is used for treatment of high blood cholesterol, hyperglycemia and hypertension . |
| 4 | Borneo | In Kiudang area ,localites uses the herb for treating various ailments. Infusion made from herb is used in poisoning caused by toxic dart(Khairunzahidah Kamsani, F. Merlin Franco, Ferry Slik, A comparative account of the traditional healing practices of healers and non-healers in the Kiudang area of Brunei Darussalam, Journal of Ethnopharmacology, Volume 256, 2020, 112788, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2020.112788. ) |
| 5 | Myanmar | In Myanmar, the Kachin community uses the stems of plant as antipyretic, analgesic, anti- inflammatory and antimalarial remedies. (Aung HT, Sein MM, Aye MM, Thu ZM. A Review of Traditional Medicinal Plants from Ka Myanmar. Natural Product Communications. March 2016. doi:10.1177/1934578X1601100310)chin State, Northern |
Phytochemical Details
| # | Phytochemical Constituents | PUBCHEM CID | References |
|---|---|---|---|
| 1 | Berberine | 2353 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 Narasimhan S, Nair GM. Effect of auxins on berberine synthesis in cell suspension culture of Coscinium fenestratum (Gaertn.) Colebr--a critically endangered medicinal liana of Western Ghats. Indian J Exp Biol. 2004 Jun;42(6):616-9. PMID: 15260115. Pongkittiphan V, Chavasiri W, Supabphol R. Antioxidant Effect of Berberine and its Phenolic Derivatives Against Human Fibrosarcoma Cells. Asian Pac J Cancer Prev. 2015;16(13):5371-6. doi: 10.7314/apjcp.2015.16.13.5371. PMID: 26225680. Rojsanga P, Gritsanapan W, Suntornsuk L. Determination of berberine content in the stem extracts of Coscinium fenestratum by TLC densitometry. Med Princ Pract. 2006;15(5):373-8. doi: 10.1159/000094272. PMID: 16888396. Nair GM, Narasimhan S, Shiburaj S, Abraham TK. Antibacterial effects of Coscinium fenestratum. Fitoterapia. 2005 Sep;76(6):585-7. doi: 10.1016/j.fitote.2005.04.005. PMID: 16112497. |
| 2 | Oxypalmatine | 10926678 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 Paulo M.M Pinho, Madalena M.M Pinto, Anake Kijjoa, Kalaya Pharadai, Jesus G Díaz, Werner Herz, Protoberberine alkaloids from Coscinium fenestratum, Phytochemistry, Volume 31, Issue 4, 1992, Pages 1403-1407, ISSN 0031-9422, https://doi.org/10.1016/0031-9422(92)80301-T. |
| 3 | Isocorypalmine | 440229 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 4 | Jatrorrhizine | 72323 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 5 | Palmatine | 19009 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 6 | Berberrubine | 72703 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 7 | Oxyberberine | 11066 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 8 | Thalifendine | 3084288 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 9 | Tetrahydroberberine (canadine) | 34458 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 10 | Noroxyhydrastinine | 89047 | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 11 | Dihydroberlambine | - | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 12 | 12,13-dihydro-8-oxo-berberine | - | Anjali Nayak, R. Jasmin Sajini, Padmavati D., R.Karthik. Chemistry and Medicinal Properties of Coscinium fenestratum (Gaertn.) Colebr (Tree Turmeric). Research J. Pharm. and Tech. 5(2): Feb. 2012; Page 198-202. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-2-29 |
| 13 | (−)-8- oxotetrahydrothalifendine | 470416 | Paulo M.M Pinho, Madalena M.M Pinto, Anake Kijjoa, Kalaya Pharadai, Jesus G Díaz, Werner Herz, Protoberberine alkaloids from Coscinium fenestratum, Phytochemistry, Volume 31, Issue 4, 1992, Pages 1403-1407, ISSN 0031-9422, https://doi.org/10.1016/0031-9422(92)80301-T. |
Pharmacological Details
| # | PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES | REFERENCES |
|---|---|---|
| 1 | Antioxidant activity | Karthika K, Gargi G, Jamuna S, Paulsamy S, Ajmal Ali M, Al-Hemaid F, Soliman Elshikh M, Lee J. The potential of antioxidant activity of methanolic extract of Coscinium fenestratum (Goetgh.) Colebr (Menispermaceae). Saudi J Biol Sci. 2019 Jul;26(5):1037-1042. doi: 10.1016/j.sjbs.2018.08.010. Epub 2018 Aug 12. PMID: 31303838; PMCID: PMC6601032. DAS K, Dang R, Sivaraman G, Ellath RP. Phytochemical Screening for Various Secondary Metabolites, Antioxidant, and Anthelmintic Activity of Coscinium fenestratum Fruit Pulp: A New Biosource for Novel Drug Discovery. Turk J Pharm Sci. 2018 Aug;15(2):156-165. doi: 10.4274/tjps.54376. Epub 2018 Jul 17. PMID: 32454655; PMCID: PMC7228015. Punitha IS, Rajendran K, Shirwaikar A, Shirwaikar A. Alcoholic stem extract of Coscinium fenestratum regulates carbohydrate metabolism and improves antioxidant status in streptozotocin-nicotinamide induced diabetic rats. Evid Based Complement Alternat Med. 2005 Sep;2(3):375-81. doi: 10.1093/ecam/neh099. Epub 2005 Jul 5. PMID: 16136216; PMCID: PMC1193540. Venukumar MR, Latha MS. Antioxidant effect of Coscinium fenestratum in carbon tetrachloride treated rats. Indian J Physiol Pharmacol. 2002 Apr;46(2):223-8. PMID: 12500498. |
| 2 | Immunomodulatory Activity | Kothalawala SD, Edward D, Harasgama JC, Ranaweera L, Weerasena OVDSJ, Niloofa R, Ratnasooriya WD, Premakumara GAS, Handunnetti SM. Immunomodulatory Activity of a Traditional Sri Lankan Concoction of Coriandrum sativum L. and Coscinium fenestratum G. Evid Based Complement Alternat Med. 2020 Sep 14;2020:9715060. doi: 10.1155/2020/9715060. PMID: 33005205; PMCID: PMC7509570. Evaluation of Immunomodulatory Activity of Ethanolic Extract of Stem Bark of Coscinium fenestratum (Gaertn.) Colebr.” (2015). |
| 3 | Antibacterial effects | Nair GM, Narasimhan S, Shiburaj S, Abraham TK. Antibacterial effects of Coscinium fenestratum. Fitoterapia. 2005 Sep;76(6):585-7. doi: 10.1016/j.fitote.2005.04.005. PMID: 16112497. G S Kumar, K N Jayaveera, C K Kumar, U P Sanjay, B M Swamy, D V Kumar ,Antimicrobial effects of Indian medicinal plants against acne-inducing bacteria, Tropical Journal of Pharmaceutical Research Vol. 6 (2) 2007: pp. 717-723 |
| 4 | Antigonococcal activity | Chomnawang MT, Trinapakul C, Gritsanapan W. In vitro antigonococcal activity of Coscinium fenestratum stem extract. J Ethnopharmacol. 2009 Apr 21;122(3):445-9. doi: 10.1016/j.jep.2009.01.036. Epub 2009 Feb 10. PMID: 19429310. |
| 5 | Anthelmintic Activity | DAS K, Dang R, Sivaraman G, Ellath RP. Phytochemical Screening for Various Secondary Metabolites, Antioxidant, and Anthelmintic Activity of Coscinium fenestratum Fruit Pulp: A New Biosource for Novel Drug Discovery. Turk J Pharm Sci. 2018 Aug;15(2):156-165. doi: 10.4274/tjps.54376. Epub 2018 Jul 17. PMID: 32454655; PMCID: PMC7228015. |
| 6 | Hypotensive effect | Wongcome T, Panthong A, Jesadanont S, Kanjanapothi D, Taesotikul T, Lertprasertsuke N. Hypotensive effect and toxicology of the extract from Coscinium fenestratum (Gaertn.) Colebr. J Ethnopharmacol. 2007 May 22;111(3):468-75. doi: 10.1016/j.jep.2006.12.019. Epub 2006 Dec 21. PMID: 17229538. Singh GB, Singh S, Bani S, Malhotra S. Hypotensive action of a Coscinium fenestratum stem extract. J Ethnopharmacol. 1990 Sep;30(2):151-5. doi: 10.1016/0378-8741(90)90004-d. PMID: 2255206. Rai, R.V., Rajesh, P.S. & Kim, HM. Medicinal use of Coscinium fenestratum (Gaertn.) Colebr.: an short review. Orient Pharm Exp Med 13, 1–9 (2013). https://doi.org/10.1007/s13596-012-0094-y |
| 7 | Anti-proliferative activity | Rojsanga P, Sukhthankar M, Krisanapun C, Gritsanapan W, Lawson DB, Baek SJ. In vitro anti-proliferative activity of alcoholic stem extract of Coscinium fenestratum in human colorectal cancer cells. Exp Ther Med. 2010 Jan;1(1):181-186. doi: 10.3892/etm_00000029. Epub 2010 Jan 1. PMID: 23136612; PMCID: PMC3490397. |
| 8 | Antidiabetic activity | Shirwaikar A, Rajendran K, Punitha IS. Antidiabetic activity of alcoholic stem extract of Coscinium fenestratum in streptozotocin-nicotinamide induced type 2 diabetic rats. J Ethnopharmacol. 2005 Feb 28;97(2):369-74. doi: 10.1016/j.jep.2004.11.034. Epub 2005 Jan 20. PMID: 15707777. Noor H. and Ashcroft S.J., Pharmacological characterization of the antihyperglycaemic properties of Tinospora crispa extract, J. Ethnopharmacol., 1998; 62: 7-13 |
| 9 | Antifeedant activity | Jayasinghe UL, Kumarihamy BM, Bandara AG, Waiblinger J, Kraus W. Antifeedant activity of some Sri Lankan plants. Nat Prod Res. 2003 Jan;17(1):5-8. doi: 10.1080/10575630290034285. PMID: 12674135. |
| 10 | Anticancer activity | R. Tungpradit, S. Sinchaikul, S. Phutraku, W. Wongkham, Shui Teinchen Anti cancer compound screening and isolation; Coscinium fenestratum, Tinospora crispa and Tinospora cordifolia Chiang Mai J. Sci., 37 (3) (2010), pp. 476-488 Min Hye Yang, Jinwoong Kim, Ikhlas A. Khan, Larry A. Walker, Shabana I. Khan, Nonsteroidal anti-inflammatory drug activated gene-1 (NAG-1) modulators from natural products as anti-cancer agents, Life Sciences, Volume 100, Issue 2, 2014, Pages 75-84, ISSN 0024-3205, https://doi.org/10.1016/j.lfs.2014.01.075. Annie Shirwaikar, K. Rajendran, I.S.R. Punitha, Antidiabetic activity of alcoholic stem extract of Coscinium fenestratum in streptozotocin-nicotinamide induced type 2 diabetic rats, Journal of Ethnopharmacology, Volume 97, Issue 2, 2005, Pages 369-374, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2004.11.034 Yang MH, Kim J, Khan IA, Walker LA, Khan SI. Nonsteroidal anti-inflammatory drug activated gene-1 (NAG-1) modulators from natural products as anti-cancer agents. Life Sci. 2014 Apr 1;100(2):75-84. doi: 10.1016/j.lfs.2014.01.075. Epub 2014 Feb 12. PMID: 24530873. Rojsanga, P., Sukhthankar, M., Krisanapun, C., Gritsanapan, W., Lawson, D. B., & Baek, S. J. (2010). In vitro anti-proliferative activity of alcoholic stem extract of Coscinium fenestratum in human colorectal cancer cells. Experimental and therapeutic medicine, 1(1), 181–186. https://doi.org/10.3892/etm_00000029 Rudeewan Tungpradit , Supachok Sinchaikul , Suree Phutrakul,Weerah Wongkham and Shui-Tein Chen,Anti-Cancer Compound Screening and Isolation: Coscinium fenestratum, Tinospora crispa and Tinospora cordifolia,Chiang Mai J. Sci. 2010; 37(3) : 476-488 Maelinda Daker, Voon Yee Lin, Gabriel Akyirem Akowuah, Chiam Nyet Cheng and Patrick Nwabueze Okechukwu, “Anti-Proliferative Activity of Standardized Methanol Extract of Coscinium fenestratum and Its Major Constituent, Berberine, Against Nasopharyngeal Carcinoma Cells”, The Natural Products Journal 2013; 3(1) . https://doi.org/10.2174/2210315511303010009 |
| 11 | Antiplasmodial activity/Antimalarial activity | Quan Le Tran, Yasuhiro Tezuka, Jun-ya Ueda, Nhan Trung Nguyen, Yukiko Maruyama, Khurshida Begum, Hye-Sook Kim, Yusuke Wataya, Qui Kim Tran, Shigetoshi Kadota, In vitro antiplasmodial activity of antimalarial medicinal plants used in Vietnamese traditional medicine, Journal of Ethnopharmacology, Volume 86, Issues 2–3, 2003, Pages 249-252, ISSN 0378-8741, https://doi.org/10.1016/S0378-8741(03)00045-X. Najib Nik A Rahman N., Furuta T., Kojima S., Takane K. and Mohd M.A., Antimalarial activity of extracts of Malaysian medicinal plants, J. Ethnopharmacol., 1999; 64: 249-254. |
| 12 | Wound healing activity | Anitha S, Ramaiah M, Suresh GS, Vaidya VP (2011) Extraction, isolation and wound healing activity of flavonoid from Coscinium fenestratum. Res J Pharm Biol Chem Sci 2:1090–1095 Thangathirupathi A., Santharam Bhuvaneswar, Evaluation of Wound Healing Activity of Coscinium fenestratum (Gaertn.) Colebr in Albino Rats,Research Journal of Pharmacology and Pharmacodynamics Year: 2011, Volume : 3, Issue: 2, 81- 87, Print ISSN: 0975-4407. |
| 13 | Biofilm inhibitory activity | Rajesh P. Shastry, P.D. Rekha, V. Ravishankar Rai, Biofilm inhibitory activity of metalloprotein AHL-lactonase from the cell-free lysate of endophytic Enterobacter species isolated from Coscinium fenestratum Gaertn., Biocatalysis and Agricultural Biotechnology, Volume 18, 2019, 101009, ISSN 1878-8181, https://doi.org/10.1016/j.bcab.2019.01.047. |
| 14 | Antiacne activity | Mohan MC, Smitha PV (2011) Phytochemical composition and antimicrobial activity of three plant preparations used in folk medicine and their synergistic properties. J Herbs Spices Med Plants 17(4):339–350 Chaudhary S (2010) Antiacne activity of some Indian herbal drugs. Int J Pharm Prof Res 1:78–80 Harisaranraj RS, Babu S, Suresh K (2010) Antimicrobial properties of selected Indian medicinal plants against acne-inducing bacteria. Ethnobot Leafl 14:84–94 |
| 15 | Antihepatotoxic activity | Venukumar MR, Latha MS (2004) Effect of Coscinium fenestratum on hepatotoxicity in rats. Indian J Exp Biol 42:792–797 |
| 16 | Central nervous system (CNS) depressant and analgesic activity | Kekuda PTR, Sudharshan SJ, Chinmaya A, Valleesha NC, Murthuza S, Achur RN (2009) Central nervous system (CNS) depressant and Analgesic activity of methanolic extracts of Nardostachys jatamansi DC. and Coscinium fenestratum Colebr. in experimental animal model. J Pharm Res 2:1716–1719 |
Marketed Products
| # | AVALAIBLE PRODUCTS | MANUFACTURERS AND SUPPLIERS | URL |
|---|---|---|---|
| 1 | way4organic Maramanjal(Coscinium Fenestratum) | way4organic | Open Url |
| 2 | Nagarjuna Anu Thailam | Nagarjuna Ayurvedic Centre | Open Url |
| 3 | Elaneer kuzhampu | Oushadhi Pharmaceuticals | Open Url |
Other Polyherbal Formulations
| # | POLYHERBAL FORMULATIONS | CITATIONS ON POLYHERBAL FORMULATIONS (PROPERTIES & ACTIVITIES) |
|---|---|---|
| 1 | Ilogen-Excel -Umamaheswari S, Mainzen Prince PS. Antihyperglycaemic effect of 'Ilogen-Excel', an ayurvedic herbal formulation in streptozotocin-induced diabetes mellitus. Acta Pol Pharm. 2007 Jan-Feb;64(1):53-61. PMID: 17665851. | P. N. Presannakumaran, P. Jayasekhar, A QHPTLC Method for the Estimation of Coscinium Fenestratum in Padoladi Ghritham- An Ayurvedic Polyherbal Formulation, International Journal of Pharma Research & Review, Feb 2017;6(2):1-11 |
Market Overview
Global End Use Market
Folk uses
Available Global Market
India , Sri Lanka, Thailand, Cambodia, Vietnam, Thailand, Malaysia, Sumatra, China
Global Manufacturer Extract
NA
Distribution in IORA Countries
Sri Lanka, Cambodia, Vietnam, Thailand (rare), Peninsular Malaysia, Sumatra, Bangka, western Java and Borneo.
Trade Data
Source Supply
Moist - semievergreen ,mixed and wet evergreen forests at 500-850 m altitude .
Trade Name
Pitchandan,Daruhaldi lakada, Maramanjal
Annual Consumption (in MT)
NA