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Plumbago indica
BOTANICAL DETAILS OF PLANT
Synonyms
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Classification
Kingdom
Plantae
Subkingdom
Superdivision
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Division
Streptophyta
Class
Equisetopsida
Subclass
Magnoliidae
Order
Caryophyllales
Family
Plumbaginaceae
Genus
Plumbago
Species
Plumbago indica
Plant Description
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Habit/Life Form
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DISTRIBUTION OF SPECIES IN INDIA
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Plant Parts Used
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System of Medicine
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Intended Use
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Traditional Application
Phytochemical Details
| # | Phytochemical Constituents | PUBCHEM CID | References |
|---|---|---|---|
| 1 | Pelargonidin | 440832 | Priyanjani, H. A. S. A., et al. |
| 2 | Cyanidin | 128861 | Priyanjani, H. A. S. A., et al. |
| 3 | Delphinidin | 68245 | Priyanjani, H. A. S. A., et al. |
| 4 | Monogalloylglucose | 129641771 | Priyanjani, H. A. S. A., et al. |
| 5 | Digalloylglucose | 129628549 | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202 |
| 6 | Plumbagin | 10205 | Priyanjani, H. A. S. A., et al. |
| 7 | 6-hydroxy plumbagin | 13468231 | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202 |
| 8 | Droserone | 442739 | Priyanjani, H. A. S. A., et al. |
| 9 | Elliptinone | 146680 | Priyanjani, H. A. S. A., et al. |
| 10 | Plumbagic acid | 92468470 | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202 |
| 11 | 3,3 –biplumbagin | 183757 | Priyanjani, H. A. S. A., et al. |
| 12 | Ayanin | 5280682 | Priyanjani, H. A. S. A., et al. |
| 13 | Azaleatin | 5281604 | Priyanjani, H. A. S. A., et al. |
| 14 | Azalein | 5321320 | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202 |
| 15 | Plumbagin | 10205 | Priyanjani, H. A. S. A., et al. |
Pharmacological Details
| # | PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES | REFERENCES |
|---|---|---|
| 1 | Antiulcer Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Sharma, Ankita, and Nimali Singh. "A multifarious potent herb: plumbago zeylanica-a mini review." Int J Recent Sci Res 6.6 (2015): 4825-9. Choudhary, Shailja, Hemlata Kaurav, and Gitika Chaudhary. "Citraka (Plumbago zeylanica): a potential rejuvenator." International journal for Research in Applied sciences and Biotechnology 8.2 (2021): 202-112. Paul, Ann Shine, Aneesul Islam, and P. Yuvaraj. "Anti-Helicobacter pylori and cytotoxic activity of detoxified root of Plumbago auriculata, Plumbago indica and Plumbago zeylanica." The Journal of Phytopharmacology 2.3 (2013): 4-8. |
| 2 | Anti-cancer Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Roy, Arpita, and Navneeta Bharadvaja. "A review on pharmaceutically important medical plant: Plumbago zeylanica." Journal of Ayurvedic and Herbal Medicine 3.4 (2017): 225-228. Rajakrishnan, R., et al. "Phytochemical evaluation of roots of Plumbago zeylanica L. and assessment of its potential as a nephroprotective agent." Saudi journal of biological sciences 24.4 (2017): 760-766. Roy, A., and N. Bharadvaja. "Establishment of the shoot and callus culture of an important medicinal plant Plumbago zeylanica." Adv Plants Agric Res 7.5 (2017): 00274. Sharma, Ankita, and Nimali Singh. "A multifarious potent herb: plumbago zeylanica-a mini review." Int J Recent Sci Res 6.6 (2015): 4825-9. Roy, A., and N. Bharadvaja. "Silver nanoparticles synthesis from a pharmaceutically important medicinal plant Plumbago zeylanica." MOJ Bioequiv Availab 3.5 (2017): 00046. Chen, Chien-An, et al. "Plumbagin, isolated from Plumbago zeylanica, induces cell death through apoptosis in human pancreatic cancer cells." Pancreatology 9.6 (2009): 797-809. Bharti, V., U. D. Gupta, and S. N. Das. "Plumbago zeylanica Extract Inhibits Cyclin D1, NF-κß and Induces Apoptosis in Oral Cancer Cells." Journal of Pharmacy Research 9.4 (2015): 264-270. Chandravanshi, Mahendra, et al. "In vitro micropropagation of important commorcial medicinal plant: Plumbago zeylanica." Adv Biol Res 8.3 (2014): 139-142. |
| 3 | Antimicrobial Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Wang, Yuan-Chuen, and Tung-Liang Huang. "Anti-Helicobacter pylori activity of Plumbago zeylanica L." FEMS Immunology & Medical Microbiology 43.3 (2005): 407-412. Jeyachandran, R., et al. "Antibacterial activity of plumbagin and root extracts of Plumbago zeylanica L." Acta Biologica Cracoviensia Series Botanica 51.1 (2009): 17-22. Dissanayake, D. M. I. H., et al. "Antimicrobial activity of Plumbago indica and ligand screening of plumbagin against methicillin-resistant Staphylococcus aureus." Journal of Biomolecular structure and dynamics 40.7 (2022): 3273-3284. Beg, Arina Z., and Iqbal Ahmad. "Effect of Plumbago zeylanica extract and certain curing agents on multidrug resistant bacteria of clinical origin." World Journal of Microbiology and Biotechnology 16 (2000): 841-844. Mandavkar, Yuvaraj D., and Sunil S. Jalalpure. "A comprehensive review on Plumbago zeylanica Linn." African Journal of pharmacy and pharmacology 5.25 (2011): 2738-2747. Jetty, Annapurna, et al. "Antimicrobial activities of neo-and 1-epineo-isoshinanolones from Plumbago zeylanica roots." Pharmaceutical biology 48.9 (2010): 1007-1011. Saha, Dibyajyoti, and Swati Paul. "Antibacterial activity of Plumbago indica." Turk J Pharm Sci 11.2 (2014): 217-222. Aleem, Mohd. "Anti-inflammatory and anti-microbial potential of Plumbago zeylanica L.: a review." Journal of Drug Delivery and Therapeutics 10.5-s (2020): 229-235. Ray, P. G., and S. K. Majumdar. "Antimicrobial activity of some Indian plants." Economic Botany 30.4 (1976): 317-320. |
| 4 | Anti-diarrheal Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Saha, Dibyajyoti, and Swati Paul. "Study of antidiarrhoeal activity of two Bangladeshi medicinal plants in castor-oil induced diarrhoea." Research Journal of Pharmacy and Technology 5.6 (2012): 800-804. Gupta, Vivek Kumar, et al. "Anti-mycobacterial activity of some medicinal plants used traditionally by tribes from Madhya Pradesh, India for treating tuberculosis related symptoms." Journal of ethnopharmacology 227 (2018): 113-120. Kabir, Mohammad Humayun, et al. "A survey of medicinal plants used by the Deb barma clan of the Tripura tribe of Moulvibazar district, Bangladesh." Journal of Ethnobiology and Ethnomedicine 10 (2014): 1-28. Thakur, Pallavi, et al. "In silico modeling for Identification of promising antimicrobials of Herbal origin against highly virulent pathogenic strains of bacteria like New Delhi Metallo-beta-lactamase-1 Escherichia coli." Int. J. Innov. Appl. Stud 4 (2013): 582-592. Goyal, Manoj, et al. "Aerva lanata: A review on phytochemistry and pharmacological aspects." Pharmacognosy reviews 5.10 (2011): 195. Singh, S. Ankul, K. Gowri, and V. Chitra. "A review on phytochemical constituents and pharmacological activities of the plant: Aerva Lanata." Research Journal of Pharmacy and Technology 13.3 (2020): 1580-1586. Kamala, Arunagiri, Sushil Kumar Middha, and Chandrakant S. Karigar. "Plants in traditional medicine with special reference to Cyperus rotundus L.: a review." 3 Biotech 8 (2018): 1-11. Vidhate, Sneha, Meena S. Deogade, and Pramod Khobragade. "Abhava Pratinidhi Dravya (substitutes for herbal drugs) acting on digestive system-A brief review." J Indian Syst Med 3 (2015): 155. Tripathi, D. M., and Nikita Semwal. "Therapeutic potential of ayurvedic herbal preparations against human diarrheal diseases." Medicinal Plants-International Journal of Phytomedicines and Related Industries 14.1 (2022): 1-6. |
| 5 | Anti-acne Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Kaur, D. A. R. S. H. P. R. E. E. T., and SHYAM BABOO Prasad. "Anti-acne activity of acetone extract of plumbago indica root." Asian Journal of Pharmaceutical and Clinical Research 9.2 (2016): 285-287. Kaur, Darshpreet, Shyam Baboo Prasad, and Surajpal Verma. "Formulation and evaluation gel from extract of Plumbago indica for acne." International Journal of Drug Delivery Technology 6.3 (2016): 95-98. Prasad, Shyam Baboo, et al. "The Recent Advancements in Field of Medicinal Plant Research With special reference to Acne Therapy." Int J Ayurveda Med 11.1 (2020): 10-4. Shrivastava, Suman, et al. "Glimpses of ethnopharmacological approaches to treat acne." Research Journal of Topical and Cosmetic Sciences 8.1 (2017): 40-49. Mohanty, B. K., et al. "Is synergy of antimicrobials the effective way of management of resistance among cosmetically significant skin microflora?." Science And Technology Against Microbial Pathogens: Research, Development and Evaluation. 2011. 164-169. Sandhya, S., et al. "A review on medicinal herbs used for acne." Research Journal of Topical and Cosmetic Sciences 2.2 (2011): 40-44. Abozeid, Dina, et al. "Medicinal Plants and their Constituents in the Treatment of Acne vulgaris." Biointerface Res. Appl. Chem 13 (2023): 189. Ardhany, Syahrida Dian. "Antibacterial activity of bawang dayak (Eleutherine sp.) and tawas ut (Ampelocissus sp.) from central kalimantan against Propionibacterium acnes." International Journal of Applied Pharmaceutics 11.3 (2019): 7-10. |
| 6 | Antioxidant Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Nile, Shivraj H., and C. N. Khobragade. "Antioxidant activity and flavonoid derivatives of Plumbago zeylanica." Journal of Natural Products 3.16 (2010): 130-133. Eldhose, Binil, Vicente Notario, and M. S. Latha. "Evaluation of phytochemical constituents and In vitro antioxidant activities of Plumbago indica root extracts." Journal of Pharmacognosy and Phytochemistry 2.4 (2013): 157-161. Mandavkar, Yuvaraj D., and Sunil S. Jalalpure. "A comprehensive review on Plumbago zeylanica Linn." African Journal of pharmacy and pharmacology 5.25 (2011): 2738-2747. Nahak, Gayatri, and Rajani Kanta Sahu. "Antioxidant activity of Plumbago zeylanica and Plumbago rosea belonging to family plumbaginaceae." Natural Product: An Indian Journal 7.2 (2011): 51-56. Beyene, Belete B., Fentahun A. Alem, and Misganaw T. Ayana. "Determination of antioxidant and antibacterial activities of leaf extracts of Plumbago zeylanica (Amira)." Cogent Chemistry 6.1 (2020): 1831715. Kanungo, S. A. T. Y. A. J. I. T., et al. "Antioxidant Activity and phytochemical evaluation of Plumbago zeylanica Linn. in vivo and in vitro." Int J Pharm Pharm Sci 4.Suppl 4 (2012): 522-26. Roy, Arpita, and Navneeta Bharadvaja. "A review on pharmaceutically important medical plant: Plumbago zeylanica." Journal of Ayurvedic and Herbal Medicine 3.4 (2017): 225-228. Rout, Jyoti Ranjan, et al. "In vivo protein profiling and Catalase Activity of Plumbago zeylanica L." Nature and Science 8.1 (2010): 87-90. Atitegeb, Abera, Mekonnen Alemayehu, and Tebeka Tesfaye. "Studies on antioxidant and antimicrobial activities of Plumbago zeylanica Linn. traditionally used for the treatments of intestinal warms and skin diseases in Ethiopia." Research Journal of Medicinal Plant 9.6 (2015): 252-263. Roy, Arpita, Neelam Sharma, and Navneeta Bharadvaja. "Assessment of phytochemical and genetic diversity analysis of Plumbago zeylanica L. accessions." Genetic Resources and Crop Evolution 69.1 (2022): 209-219. |
| 7 | Anti-fertility Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Jain, Paras, et al. "Pharmacological profiles of ethno-medicinal plant: Plumbago zeylanica l.-A review." Int J Pharm Sci Rev Res 24.1 (2014): 157-63. Subhash, Kakad, A. S. Wabale, and M. N. Kharde. "Phytochemical screening and antimicrobial studies on Plumbago zeylanica L." Adv. Biores 4.3 (2013): 115-117. Ravali, Porandla, and C. P. Kumar. "A review on different activities of medicinal plant of Plumbago indica L." World J Pharm Res 14 (2018): 473-478. Borhade, Pravin Sopan, et al. "Pharmacognostic and Phytochemical Investigations of Plumbago zeylanica Linn. root." Journal of Pharmacognosy and Phytochemistry 2.6 (2014): 83-88. Chakraverty, Raja, and Sudeshna Sasmal. "A Systematic review on natural based anti-fertility drugs." Acta Sci. Pharm. Sci 2.12 (2018): 35-40. |
| 8 | Wound Healing Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Kodati, Devender Rao, Shashidher Burra, and G. P. Kumar. "Evaluation of wound healing activity of methanolic root extract of Plumbago zeylanica L. in wistar albino rats." Asian Journal of Plant Science and Research 1.2 (2011): 26-34. Roy, Arpita, and Navneeta Bharadvaja. "A review on pharmaceutically important medical plant: Plumbago zeylanica." Journal of Ayurvedic and Herbal Medicine 3.4 (2017): 225-228. Jain, Paras, et al. "Pharmacological profiles of ethno-medicinal plant: Plumbago zeylanica l.-A review." Int J Pharm Sci Rev Res 24.1 (2014): 157-63. Sharma, Ankita, and Nimali Singh. "A multifarious potent herb: plumbago zeylanica-a mini review." Int J Recent Sci Res 6.6 (2015): 4825-9. Reddy, J. Suresh, P. Rajeswara Rao, and Mada S. Reddy. "Wound healing effects of Heliotropium indicum, Plumbago zeylanicum and Acalypha indica in rats." Journal of ethnopharmacology 79.2 (2002): 249-251. Reddy, J. Suresh, P. Rajeswara Rao, and Mada S. Reddy. "Wound healing effects of Heliotropium indicum, Plumbago zeylanicum and Acalypha indica in rats." Journal of ethnopharmacology 79.2 (2002): 249-251. |
| 9 | Analgesic and Anti-inflammatory Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Sheeja, E., S. B. Joshi, and D. C. Jain. "Bioassay-guided isolation of anti-inflammatory and antinociceptive compound from Plumbago zeylanica leaf." Pharmaceutical biology 48.4 (2010): 381-387. Thanigavelan, V., et al. "Hydroalcoholic extract of Plumbago zeylanica Linn root bark exhibit analgesic and anti-inflammatory activities in experimental rat models." Am J Pharm Health Res 2.4 (2014): 209-221. Ittiyavirah, Sibi P., et al. "Anti-inflammatory and analgesic activities of Plumbago capensis and Plumbago indica." Advances in Pharmacology and Toxicology 13.1 (2012): 47. Ibrahim, Mohammed, et al. "Preliminary Phytochemical and Pharmacological Screenings of Plumbago indica L. and Alpinia conchigera Griff." Dhaka University Journal of Pharmaceutical Sciences 17.1 (2018): 73-79. Sengupta, Rupa, Sonali D. Sheorey, and Madhuri A. Hinge. "Analgesic and anti-inflammatory plants: an updated review." International Journal of Pharmaceutical Sciences Review and Research 12.2 (2012): 114-119. Rajakrishnan, R., et al. "Phytochemical evaluation of roots of Plumbago zeylanica L. and assessment of its potential as a nephroprotective agent." Saudi journal of biological sciences 24.4 (2017): 760-766. Roy, Arpita, and Navneeta Bharadvaja. "A review on pharmaceutically important medical plant: Plumbago zeylanica." Journal of Ayurvedic and Herbal Medicine 3.4 (2017): 225-228. Makchuchit, Sunita, Ruchilak Rattarom, and Arunporn Itharat. "The anti-allergic and anti-inflammatory effects of Benjakul extract (a Thai traditional medicine), its constituent plants and its some pure constituents using in vitro experiments." Biomedicine & Pharmacotherapy 89 (2017): 1018-1026. Gupta, Nilesh, et al. "Review of some important medicinal plants possesses anti-inflammatory activity." Research journal of Pharmacy and Technology 4.10 (2011): 1506-1512. Shukla, Babita, et al. "Phytochemistry and pharmacological studies of Plumbago zeylanica L.: a medicinal plant review." Clinical Phytoscience 7 (2021): 1-11. |
| 10 | Antiinfluenza Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Chavan, Rahul Dilip, et al. "Assessment of anti-influenza activity and hemagglutination inhibition of Plumbago indica and Allium sativum extracts." Pharmacognosy Research 8.2 (2016): 105. Gebre-Mariam, T., et al. "Antiviral activities of some Ethiopian medicinal plants used for the treatment of dermatological disorders." Journal of ethnopharmacology 104.1-2 (2006): 182-187. Kaliyaperumal, Saravanan, et al. "Antiviral phytocompounds for drug development: a data mining studies." Phytochemicals as Lead Compounds for New Drug Discovery. Elsevier, 2020. 239-244. Panyod, Suraphan, Chi-Tang Ho, and Lee-Yan Sheen. "Dietary therapy and herbal medicine for COVID-19 prevention: A review and perspective." Journal of traditional and complementary medicine 10.4 (2020): 420-427. Sargin, Seyid Ahmet. "Potential anti-influenza effective plants used in Turkish folk medicine: A review." Journal of Ethnopharmacology 265 (2021): 113319. Bandara, H. M. S. K. H., et al. "Antiviral Activities of Some Traditional Medicinal Plants of Sri Lanka." Current Traditional Medicine 9.6 (2023): 25-38. Kim, Seonjeong, et al. "Antiviral Activity of Plant-derived Natural Products against Influenza Viruses." 생명과학회지 32.5 (2022): 375-390. |
| 11 | Hepatoprotective Activity | Priyanjani, H. A. S. A., et al. "Propagation, phytochemistry and pharmacology of plumbago indica-a review." Journal of Pharmaceutical Research International (2021).33(42B): 188-202. Kanchana, N., and A. Mohamed Sadiq. "Hepatoprotective effect of Plumbago zeylanica on paracetamol induced liver toxicity in rats." Int J Pharm Pharm Sci 3.1 (2011): 151-154. Kumar, Rajesh, et al. "Hepatoprotective activity of aerial parts of Plumbago zeylanica linn against carbon tetrachloride-induced hepatotoxicity in rats." Int J Pharmacy Pharmaceut Sci 1.1 (2009): 171-175. Mandavkar, Yuvaraj D., and Sunil S. Jalalpure. "A comprehensive review on Plumbago zeylanica Linn." African Journal of pharmacy and pharmacology 5.25 (2011): 2738-2747. Selim, Nabil Mohamed, et al. "Phytochemical profiling and anti-fibrotic activities of Plumbago indica L. and Plumbago auriculata Lam. in thioacetamide-induced liver fibrosis in rats." Scientific Reports 12.1 (2022): 9864. Selim, Nabil Mohamed, et al. "Phytochemical profiling and anti-fibrotic activities of Plumbago indica L. and Plumbago auriculata Lam. in thioacetamide-induced liver fibrosis in rats." Scientific Reports 12.1 (2022): 9864. Rajakrishnan, R., et al. "Phytochemical evaluation of roots of Plumbago zeylanica L. and assessment of its potential as a nephroprotective agent." Saudi journal of biological sciences 24.4 (2017): 760-766. Roy, A., and N. Bharadvaja. "Silver nanoparticles synthesis from a pharmaceutically important medicinal plant Plumbago zeylanica." MOJ Bioequiv Availab 3.5 (2017): 00046. Rajasekaran, Aiyalu, and Muthusamy Periasamy. "Protective effect of ethanolic root extract of Plumbago indica L. on paracetamol induced hepatotoxicity in rats." Afr J Pharm Pharmacol 5 (2011): 2330-4. Phaneendra, Pasumarthi, et al. "Hepatoprotective herbs: an overview." Int J Pharm Res Dev 3 (2011): 105-111. Arsul, VILAS A., SUPRIYA R. Wagh, and R. V. Mayee. "Hepatoprotective activity of livergen, a polyherbal formulation against carbon tetrachloride induced hepatotoxicity in rats." Int J Pharma Pharmac Sci 3 (2011): 228-31. |
Market Overview
Global End Use Market
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Available Global Market
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Global Manufacturer Extract
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Distribution in IORA Countries
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Trade Data
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Annual Consumption (in MT)
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