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Kingdom
Plantae
Subkingdom
Superdivision
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Division
Thacheophyta
Class
Mangoliopsida
Subclass
Order
Fabales
Family
Fabaceae
Genus
Chamaecrista Moench
Species
Cassia absus L.
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| # | Phytochemical Constituents | PUBCHEM CID | References |
|---|---|---|---|
| 1 | Cycloartenol | 92110 | Ahmad, Saeed, et al. |
| 2 | Chaksine | 135438603 | Ahmad, Saeed, et al. |
| 3 | Isochaksine | 135339950 | Ahmad, Saeed, et al. |
| 4 | Chrysophanol | 10208 | Ahmad, Saeed, et al. |
| 5 | Aloe-emodin | 10207 | Ahmad, Saeed, et al. |
| 6 | Cycloartenol | 92110 | Ahmad, Saeed, et al. |
| # | PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES | REFERENCES |
|---|---|---|
| 1 | Antioxidant activity | Ahmad, Saeed, et al. "Phytochemistry and pharmacological potential of Cassia absus–a review." Journal of Pharmacy and Pharmacology 70.1 (2018): 27-41. Kumaran, A., and R. Joel Karunakaran. "Antioxidant activity of Cassia auriculata flowers." Fitoterapia 78.1 (2007): 46-47. Manonmani, G., et al. "Antioxidant activity of Cassia fistula (Linn.) flowers in alloxan induced diabetic rats." Journal of Ethnopharmacology 97.1 (2005): 39-42. Jayaraman, P., et al. "Comparative analysis of antioxidant activity and phytochemical potential of Cassia absus Linn., Cassia auriculata Linn. and Cassia fistula Linn." Indian J Drugs & Dis 3 (2014): 1. Khan, Barkat Ali, et al. "Investigation of the effects of extraction solvent/technique on the antioxidant activity of Cassia fistula L." Journal of Medicinal Plants Research 6.3 (2012): 500-503. Bhalodia, Nayan R., R. N. Acharya, and V. J. Shukla. "Evaluation of in vitro Antioxidant Activity of hydroalcoholic seed extratcs of Cassia fistula linn." Free Radicals and Antioxidants 1.1 (2011): 68-76. Yen, Gow-Chin, and Da-Yon Chuang. "Antioxidant properties of water extracts from Cassia tora L. in relation to the degree of roasting." Journal of agricultural and food chemistry 48.7 (2000): 2760-2765. Ilavarasan, Raju, Moni Malika, and Subramanian Venkataraman. "Anti-inflammatory and antioxidant activities of Cassia fistula Linn bark extracts." African journal of traditional, complementary and alternative medicines 2.1 (2005): 70-85. Ahmad, Saeed, et al. "In vitro bioactivity of extracts from seeds of Cassia absus L. growing in Pakistan." Journal of Herbal Medicine 16 (2019): 100258. |
| 2 | Antitrypsin activity | Ahmad, Saeed, et al. "Phytochemistry and pharmacological potential of Cassia absus–a review." Journal of Pharmacy and Pharmacology 70.1 (2018): 27-41. Tripathi, Vinayak R., Shailendra Kumar, and Satyendra K. Garg. "A study on trypsin, Aspergillus flavus and Bacillus sp. protease inhibitory activity in Cassia tora (L.) syn Senna tora (L.) Roxb. seed extract." BMC Complementary and Alternative Medicine 11.1 (2011): 1-8. Dias, Lucas P., et al. "A trypsin inhibitor purified from Cassia leiandra seeds has insecticidal activity against Aedes aegypti." Process Biochemistry 57 (2017): 228-238. Pandey, Ankesh, Reena Yadav, and Indraneel Sanyal. "Evaluating the pesticidal impact of plant protease inhibitors: lethal weaponry in the co‐evolutionary battle." Pest Management Science 78.3 (2022): 855-868. Martins, Thiago F., et al. "A Bowman–Birk Inhibitor from the Seeds of Luetzelburgia auriculata Inhibits Staphylococcus aureus Growth by Promoting Severe Cell Membrane Damage." Journal of natural products 81.7 (2018): 1497-1507. de Souza, Adson Ávila, et al. "Chia (Salvia hispanica L.) seeds contain a highly stable trypsin inhibitor with potential for bacterial management alone or in drug combination therapy with oxacillin." Probiotics and Antimicrobial Proteins 15.5 (2023): 1221-1233. Costa, Helen PS, et al. "JcTI-I: a novel trypsin inhibitor from Jatropha curcas seed cake with potential for bacterial infection treatment." Frontiers in Microbiology 5 (2014): 5. Al Munna, Md Abdullah, et al. "Journal of Bangladesh Agricultural University." J Bangladesh Agril Univ 21.3 (2023): 397-405. |
| 3 | Antiglycation activity | Ahmad, Saeed, et al. "Phytochemistry and pharmacological potential of Cassia absus–a review." Journal of Pharmacy and Pharmacology 70.1 (2018): 27-41. Hussain, Fatma, Muhammad Shahid, and Komal Javed. "Antioxidant, antiglycation and alpha Amylase inhibitory activities of Cassia absus seeds." Int. Sci. Org. Curr. Sci. Perspect 2.1 (2015): 5-9. Nancy, Pandita, and Vaidya Ashlesha. "Pharmacognostic and phytochemical studies of Cassia absus seeds extract." Int J Pharm Pharm Sci 8.1 (2015): 325-32. Hussain, Fatma, Muhammad Shahid, and Komal Javed. "Antioxidant, antiglycation and alpha Amylase inhibitory activities of Cassia absus seeds." Int. Sci. Org. Curr. Sci. Perspect 2.1 (2015): 5-9. Chinchansure, Ashish A., et al. "Recent development of plant products with anti-glycation activity: a review." RSC Advances 5.39 (2015): 31113-31138. Perera, P. R. D., S. Ekanayaka, and K. K. D. S. Ranaweera. "In vitro antiglycation activity of some medicinal plants used in diabetes mellitus." Medicinal Aromatic Plants 2.6 (2013): 143-5. |
| 4 | Antidiabetic activity | Ahmad, Saeed, et al. "Phytochemistry and pharmacological potential of Cassia absus–a review." Journal of Pharmacy and Pharmacology 70.1 (2018): 27-41. Nambirajan, Gayathri, et al. "Evaluation of antidiabetic activity of bud and flower of Avaram Senna (Cassia auriculata L.) In high fat diet and streptozotocin induced diabetic rats." Biomedicine & Pharmacotherapy 108 (2018): 1495-1506. Gupta, Shipra, et al. "Elucidation of mechanism of action of Cassia auriculata leaf extract for its antidiabetic activity in streptozotocin-induced diabetic rats." Journal of Medicinal Food 13.3 (2010): 528-534. Daisy, P., G. Feril, and J. Kani. "Evaluation of antidiabetic activity of various extracts of Cassia auriculata Linn. bark on streptozotocin-induced diabetic wistar rats." International Journal of Pharmacy and Pharmaceutical Sciences 4.4 (2012): 312-18. Hussain, Fatma, Muhammad Shahid, and Komal Javed. "Antioxidant, antiglycation and alpha Amylase inhibitory activities of Cassia absus seeds." Int. Sci. Org. Curr. Sci. Perspect 2.1 (2015): 5-9. Thirumal, Sivakumar, and T. Sivakumar. "Synthesis of silver nanoparticles using Cassia auriculata leaves extracts and their potential antidiabetic activity." Int. j. botany stud 6.3 (2021): 35-38. Ali, Md Ashraf. "Cassia fistula Linn: a review of phytochemical and pharmacological studies." Int J Pharm Sci Res 5.6 (2014): 2125-2130. Fathima, Hena Mariam, Lakshmi Thangavelu, and Anitha Roy. "Anti-diabetic activity of cassia fistula (alpha amylase–inhibitory effect)." Journal of Advanced Pharmacy Education & Research| Apr-Jun 8.2 (2018): 13. Jarald, E. E., et al. "Biochemical evaluation of the hypoglycemic effects of extract and fraction of Cassia fistula Linn. in alloxan-induced diabetic rats." Indian journal of pharmaceutical sciences 75.4 (2013): 427. Pari, L., and M. Latha. "Effect of Cassia auriculata flowers on blood sugar levels, serum and tissue lipids in streptozotocin diabetic rats." Singapore Med J 43.12 (2002): 617-621. |
| 5 | Antibacterial activity | Ahmad, Saeed, et al. "Phytochemistry and pharmacological potential of Cassia absus–a review." Journal of Pharmacy and Pharmacology 70.1 (2018): 27-41. Panda, Sujogya K., L. P. Padhi, and G. Mohanty. "Antibacterial activities and phytochemical analysis of Cassia fistula (Linn.) leaf." Journal of advanced pharmaceutical technology & research 2.1 (2011): 62. Sharma, Sarika, et al. "Antibacterial activity of Cassia tora leaves." Int J Pharm & Biol Arch 1.1 (2010): 84-6. Suresh, D., et al. "Green synthesis of multifunctional zinc oxide (ZnO) nanoparticles using Cassia fistula plant extract and their photodegradative, antioxidant and antibacterial activities." Materials Science in Semiconductor Processing 31 (2015): 446-454. Abo, K. A., S. W. Lasaki, and A. A. Adeyemi. "Laxative and antimicrobial properties of Cassia species growing in Ibadan." Nigerian Journal of Natural Products and Medicine 3 (1999): 47-50. Ahmad, Saeed, et al. "In vitro bioactivity of extracts from seeds of Cassia absus L. growing in Pakistan." Journal of Herbal Medicine 16 (2019): 100258. Duraipandiyan, V., and S. Ignacimuthu. "Antibacterial and antifungal activity of Cassia fistula L.: An ethnomedicinal plant." Journal of ethnopharmacology 112.3 (2007): 590-594. Hatano, Tsutomu, et al. "Phenolic constituents of Cassia seeds and antibacterial effect of some naphthalenes and anthraquinones on methicillin-resistant Staphylococcus aureus." Chemical and Pharmaceutical Bulletin 47.8 (1999): 1121-1127. Govindarajan, M., et al. "Antibacterial activity of Acalypha indica L." Eur Rev Med Pharmacol Sci 12.5 (2008): 299-302. |
| 6 | Anti-inflammatory activity | Ahmad, Saeed, et al. "Phytochemistry and pharmacological potential of Cassia absus–a review." Journal of Pharmacy and Pharmacology 70.1 (2018): 27-41. Ilavarasan, Raju, Moni Malika, and Subramanian Venkataraman. "Anti-inflammatory and antioxidant activities of Cassia fistula Linn bark extracts." African journal of traditional, complementary and alternative medicines 2.1 (2005): 70-85. Ilavarasan, Raju, Moni Malika, and Subramanian Venkataraman. "Anti-inflammatory and antioxidant activities of Cassia fistula Linn bark extracts." African journal of traditional, complementary and alternative medicines 2.1 (2005): 70-85. Manogaran, S., and N. Sulochana. "Anti-inflammatory activity of Cassia aauriculata." Ancient Science of Life 24.2 (2004): 65. Kulkarni, Anusha, et al. "Phytochemical analysis of Cassia fistula and its in vitro antimicrobial, antioxidant and anti-inflammatory activities." Advancement in Medicinal Plant Research 3.1 (2015): 8-17. Hou, Jingyi, et al. "Anti-inflammatory effects of aurantio-obtusin from seed of Cassia obtusifolia L. through modulation of the NF-κB pathway." Molecules 23.12 (2018): 3093. Dixit, Gouri, et al. "Formulation and evaluation of polyherbal gel for anti-inflammatory activity." International Journal of Pharmaceutical Sciences and Research 4.3 (2013): 1186. |
| 7 | Reproductive toxicity | Ahmad, Saeed, et al. "Phytochemistry and pharmacological potential of Cassia absus–a review." Journal of Pharmacy and Pharmacology 70.1 (2018): 27-41. Hamedi, Azadeh, et al. "Reproductive toxicity of Cassia absus seeds in female rats: possible progesteronic properties of chaksine and b-sitosterol." Pharmaceutical Chemistry Journal 49 (2015): 268-274. Hamedi, Azadeh, et al. "Reproductive toxicity of Cassia absus seeds in female rats: possible progesteronic properties of chaksine and b-sitosterol." Pharmaceutical Chemistry Journal 49 (2015): 268-274. Ahmad, Saeed, et al. "Phytochemistry and pharmacological potential of Cassia absus–a review." Journal of Pharmacy and Pharmacology 70.1 (2018): 27-41. Yadav, Rajesh, and G. C. Jain. "Effect of aqueous extract of seeds of Cassia fistula on the uterine biochemical milieu of female albino rats." Pharmacology 1 (2009): 859-867. Sharma, Akanksha, Amit Kumar, and Vikas Jaitak. "Pharmacological and chemical potential of Cassia fistula L-a critical review." Journal of Herbal Medicine 26 (2021): 100407. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). "Scientific Opinion on the safety and efficacy of cassia gum for dogs and cats based on a dossier submitted by Intercolloid (UK) Ltd." EFSA Journal 12.11 (2014): 3901. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). "Scientific Opinion on the safety and efficacy of cassia gum for dogs and cats based on a dossier submitted by Glycomer GmbH." EFSA Journal 12.11 (2014): 3899. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). "Scientific Opinion on the safety and efficacy of cassia gum for dogs and cats based on a dossier submitted by Glycomer GmbH." EFSA Journal 12.11 (2014): 3899. EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). "Scientific Opinion on the safety and efficacy of cassia gum (Galactogum) for dogs and cats based on a dossier submitted by Galacto Naturstoffe GmbH." EFSA Journal 12.11 (2014): 3900. |
| 8 | Antifungal activity | Ahmad, Saeed, et al. "Phytochemistry and pharmacological potential of Cassia absus–a review." Journal of Pharmacy and Pharmacology 70.1 (2018): 27-41. Duraipandiyan, V., and S. Ignacimuthu. "Antibacterial and antifungal activity of Cassia fistula L.: An ethnomedicinal plant." Journal of ethnopharmacology 112.3 (2007): 590-594. Phongpaichit, Souwalak, et al. "Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L." Songklanakarin J Sci Technol 26.5 (2004): 741-748. Bhalodia, N. R., et al. "In vitro antibacterial and antifungal activities of Cassia fistula Linn. fruit pulp extracts." Ayu 33.1 (2012): 123. Panda, S. K., S. Brahma, and S. K. Dutta. "Selective antifungal action of crude extracts of Cassia fistula L.: A preliminary study on Candida and Aspergillus species." Malaysian journal of microbiology 6.1 (2010): 62-68. Sony, P., et al. "In vitro antifungal activity of cassia fistula extracts against fluconazole resistant strains of Candida species from HIV patients." Journal de mycologie medicale 28.1 (2018): 193-200. Borisutpeth, Manassanan, et al. "In vitro antifungal activity of Cassia fistula L. against selected pathogenic water molds." International Journal of Phytomedicine 6.2 (2014): 237. |
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