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Holarrhena antidysenterica (L.) Wall.
BOTANICAL DETAILS OF PLANT
Synonyms
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Classification
Kingdom
Plantae
Subkingdom
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Superdivision
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Division
Streptophyta
Class
Magnoliopsida
Subclass
Magnoliidae
Order
Gentianales
Family
Apocynaceae
Genus
Holarrhena
Species
Holarrhena antidysenterica
Plant Description
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Habit/Life Form
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DISTRIBUTION OF SPECIES IN INDIA
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Plant Parts Used
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System of Medicine
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Intended Use
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Traditional Application
Phytochemical Details
| # | Phytochemical Constituents | PUBCHEM CID | References |
|---|---|---|---|
| 1 | Butin | 92775 | Basu BD, Kirtikar K, Blatter E. 1999. Indian medicinal plants.end. International Book Distributors. Mishra, M., Shukla, Y. N., & Kumar, S. (2000). Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry, 54(8), 835-838. |
| 2 | Isobutrin | 5281256 | Basu BD, Kirtikar K, Blatter E. 1999. Indian medicinal plants.end. International Book Distributors. Mishra, M., Shukla, Y. N., & Kumar, S. (2000). Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry, 54(8), 835-838. |
| 3 | Chalcones | 162517550 | Basu BD, Kirtikar K, Blatter E. 1999. Indian medicinal plants.end. International Book Distributors. Mishra, M., Shukla, Y. N., & Kumar, S. (2000). Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry, 54(8), 835-838. |
| 4 | aurones | 1801100 | Basu BD, Kirtikar K, Blatter E. 1999. Indian medicinal plants.end. International Book Distributors. Mishra, M., Shukla, Y. N., & Kumar, S. (2000). Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry, 54(8), 835-838. |
| 5 | palasitrin | 42607742 | Basu BD, Kirtikar K, Blatter E. 1999. Indian medicinal plants.end. International Book Distributors. Mishra, M., Shukla, Y. N., & Kumar, S. (2000). Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry, 54(8), 835-838. |
| 6 | coreopsin | 12303943 | Basu BD, Kirtikar K, Blatter E. 1999. Indian medicinal plants.end. International Book Distributors. Mishra, M., Shukla, Y. N., & Kumar, S. (2000). Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry, 54(8), 835-838. |
| 7 | isocoreopsin | 12309899 | Basu BD, Kirtikar K, Blatter E. 1999. Indian medicinal plants.end. International Book Distributors. Mishra, M., Shukla, Y. N., & Kumar, S. (2000). Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry, 54(8), 835-838. |
| 8 | monospermoside | 42607524 | Basu BD, Kirtikar K, Blatter E. 1999. Indian medicinal plants.end. International Book Distributors. Mishra, M., Shukla, Y. N., & Kumar, S. (2000). Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry, 54(8), 835-838. |
| 9 | Myricyl alcohol | 68972 | Basu BD, Kirtikar K, Blatter E. 1999. Indian medicinal plants.end. International Book Distributors. Mishra, M., Shukla, Y. N., & Kumar, S. (2000). Euphane triterpenoid and lipid constituents from Butea monosperma. Phytochemistry, 54(8), 835-838. |
| 10 | Palmitic acid | 134223719 | Sindhia V, Bairwa R. Plant review: Butea monosperma. Int J Pharm Clin Res, 2010; 2:90-94. |
| 11 | Arachidic acid | 10467 | Sindhia V, Bairwa R. Plant review: Butea monosperma. Int J Pharm Clin Res, 2010; 2:90-94. |
| 12 | Lignoceric acid | 11197 | Sindhia V, Bairwa R. Plant review: Butea monosperma. Int J Pharm Clin Res, 2010; 2:90-94. |
| 13 | Glucose | 5793 | Sindhia V, Bairwa R. Plant review: Butea monosperma. Int J Pharm Clin Res, 2010; 2:90-94. |
Pharmacological Details
| # | PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES | REFERENCES |
|---|---|---|
| 1 | Anti-asthmatic | Kumari, Poonam, et al. "Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review." Current Pharmacology Reports 8.3 (2022): 188-204. Jain, Sourabh, and P. K. Dubey. "Butea monosperma (Lam.) Taub: Review on its chemistry, morphology, ethnomedical uses, phytochemistry and pharmacological activities." Journal of Drug Delivery and Therapeutics 13.4 (2023): 137-144. Khedkar, Dinesh D., and Nitin M. Atre. "Medicinal flora of melghat for asthma: A review." Journal of Pharmacognosy and Phytochemistry 8.2 (2019): 2091-2095. Rahmatullah, Mohammed, et al. "Medicinal formulations of a Kanda tribal healer–a tribe on the verge of disappearance in Bangladesh." African Journal of Traditional, Complementary and Alternative Medicines 10.2 (2013): 213-222. Choudhary, Shailja, Hemlata Kaurav, and Gitika Chaudhary. "Medicinal importance of in ayurveda and modern sciences: A Ephedra gerardiana." Asian Journal of Pharmacy and Pharmacology 7.3 (2021): 110-117. |
| 2 | Anti-anthelmintic | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Mahanthesh, M. T., et al. "Swiss ADME prediction of phytochemicals present in Butea monosperma (Lam.) Taub." Journal of Pharmacognosy and Phytochemistry 9.3 (2020): 1799-1809. Somayaji, Ashwini, and Karunakar Hegde. "A review on phrmacological profile of Butea monosperma." International Journal of Phytopharmacology 7 (2016): 237-249.
Chouhan, Ashwin Singh, et al. "Holarrhena pubescens wall ex. don: a review on ethnobotanical, phytochemical and pharmacological profile." Indian J Drugs 5 (2017): 71-77. Jolly, C. I., and Nisha R. Mechery. "Comparative Pharmacognostical, Physicochemical And Antibacterial Studies On Seeds Of Holarrhena Antidysenterica Wall And Wrightia Tinctoria R. Br." Indian journal of pharmaceutical sciences 58.2 (1996): 51. |
| 3 | Anticonvulsant activity | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Sangale, Prakash, Dhananjay Deshmukh, and Rajesh Bhambere. "Anticonvulsant effect of leaf and bark of Erythrina variegata linn and Butea monosperma (LAM) Taub in different experimental convulsion model in rats." PharmaTutor 3.5 (2015): 19-23. Kumari, Poonam, et al. "Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review." Current Pharmacology Reports 8.3 (2022): 188-204. Talubmook, Chusri, and Nopparat Buddhakala. "Antioxidant and antidiabetic activities of flower extract from Butea monosperma (Lam.) Taub." GSTF International Journal on Bioformatics & Biotechnology (JBio) 2.1 (2012): 7. Nautiyal, Vinod, et al. "Antiinflammatory Activity of Aqueous Bark Extract of Butea monosperma (Lam.) Taub." Asian Journal of Chemistry 23.9 (2011): 4219-4220. |
| 4 | Anti-diarrhoeal | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Mishra, Ashish, Saket Verma, and Abhinav Prasoon Mishra. "A plant review: Butea monosperma (Lam.) Kuntze." Res. J. Pharm. Biol. Chem. Sci 3.1 (2012): 700-714. Gupta, Arti, et al. "Evaluation of protective effect of Butea monosperma (lam.) Taub in experimental hepatotoxicity in rats." Journal of Pharmacology and Pharmacotherapeutics 3.2 (2012): 183-185. More, B. H., et al. "Ethnobotany & Ethanopharmacology of Butea Monosperma (Lam) Kuntze-A Compressive Review." Am J PharmTech Res 2.5 (2012): 138-159. Gopinath, G., M. Thirumal, and P. R. Kumar. "Holarrhena antidysenterica Linn.–A Review." Research Journal of Pharmacy and Technology 13.4 (2020): 2013-2018. Murugan, Sasikumar, et al. "Anti-diarrhoeal activity of a polyherbal formulation in rats and elucidation of its cellular mechanisms." Avicenna journal of phytomedicine 10.4 (2020): 417. |
| 5 | Wound healing | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Mishra, Ashish, Saket Verma, and Abhinav Prasoon Mishra. "A plant review: Butea monosperma (Lam.) Kuntze." Res. J. Pharm. Biol. Chem. Sci 3.1 (2012): 700-714. Sindhia, V. R., and R. Bairwa. "Plant review: Butea monosperma." International journal of pharmaceutical and clinical research 2.2 (2010): 90-94. Sinha, Snehadri, et al. "Evaluation of phytochemical and pharmacological aspects of Holarrhena antidysenterica (Wall.): A comprehensive review." Journal of Pharmacy research 6.4 (2013): 488-492. |
| 6 | Anti-filarial | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Kumari, Poonam, et al. "Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review." Current Pharmacology Reports 8.3 (2022): 188-204. Upadhyay, Yashi. "Palasha, a holy plant: Its phytochemistry, biological effects, and therapeutic uses." International Journal of Green Pharmacy (IJGP) 16.4 (2022). Hossain, Md, et al. "Importance of some Bangladeshi ethnomedicinal plants: A review." European Journal of Medicinal Plants 16.4 (2016): 1-14. Mastiholimath, V. S. Development and evaluation of polyherbal formulations for antidiabetic and antiphypertensive activities. Diss. Rajiv Gandhi University of Health Sciences (India), 2008. |
| 7 | Anti-ulcer | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Methaniya, Dharti, Riddhi Rathore, and Hitesh Solanki. "BUTEA MONOSPERMA: ETHANOMEDICINAL STUDIES AND PHARMACOLOGY: A REVIEW." International Association of Biologicals and Computational Digest 2.1 (2023): 222-229. Neupane, Asmit, and Pratikshya Aryal. "Medicinal Values of Butea monosperma: A." Asian Journal of Pharmacognosy 6.2 (2022): 6-13. Surin, William Rasican, and Kavya Ananthaswamy. "Recent advances on the pharmacological profile of Butea monosperma." GERF Bull Biosci 2.1 (2011): 33-40. Bafna, Pallavi, and Subhash Bodhankar. "Gastrointestinal effects of Mebarid®, an ayurvedic formulation, in experimental animals." Journal of ethnopharmacology 86.2-3 (2003): 173-176. Srivastava, Rajani. "A review on phytochemical, pharmacological, and pharmacognostical profile of Wrightia tinctoria: Adulterant of kurchi." Pharmacognosy reviews 8.15 (2014): 36. Sapkota, B., and V. Jain. "Evaluation of anti-ulcer activity of Citrus maxima (brum.) leaves extract in experimental animals." Journal of Clinical and Experimental Pharmacology 11.2 (2021): 1-6. |
| 8 | Anti-dopanergic Activity | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Datta, Sanjana, and R. Mishra. "Plumbago zeylinica Linn.(Chitrak)-Review as rasayan (rejuvenator/antiaging)." Int J Res Pharm Biomed Sci 3.1 (2012): 250-67. Mandavkar, Yuvaraj D., and Sunil S. Jalalpure. "A comprehensive review on Plumbago zeylanica Linn." African Journal of pharmacy and pharmacology 5.25 (2011): 2738-2747. Dey, Abhijit, Anuradha Mukherjee, and Madhubrata Chaudhury. "Alkaloids from apocynaceae: origin, pharmacotherapeutic properties, and structure-activity studies." Studies in Natural Products Chemistry 52 (2017): 373-488. Ambhore, Nilesh Sudhakar, et al. "Determination of Histamine H3-Receptor Antagonist Conessine in Wistar Rat Plasma by a Rapid and Sensitive RP-UFLC Method: Application to a Pharmacokinetic Study." Journal of Young Pharmacists 12.1 (2020): 55. Dey, Abhijit, Anuradha Mukherjee, and Madhubrata Chaudhury. "Alkaloids from apocynaceae: origin, pharmacotherapeutic properties, and structure-activity studies." Studies in Natural Products Chemistry 52 (2017): 373-488. |
| 9 | Osteogenic activity | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Kumari, Poonam, et al. "Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review." Current Pharmacology Reports 8.3 (2022): 188-204. Mahalik, Gyanranjan. "Comparative Analysis of Phytochemical and Antimicrobial Activity of Butea monosperma (Lam.) Taub. and Pongamia pinnata (L.) Pierre: A." (2020). |
| 10 | Anti-diabetic Activity | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Talubmook, Chusri, and Nopparat Buddhakala. "Antioxidant and antidiabetic activities of flower extract from Butea monosperma (Lam.) Taub." GSTF International Journal on Bioformatics & Biotechnology (JBio) 2.1 (2012): 7. Kumari, Poonam, et al. "Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review." Current Pharmacology Reports 8.3 (2022): 188-204. Kumari, Poonam, et al. "Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review." Current Pharmacology Reports 8.3 (2022): 188-204. Mahanthesh, M. T., et al. "Swiss ADME prediction of phytochemicals present in Butea monosperma (Lam.) Taub." Journal of Pharmacognosy and Phytochemistry 9.3 (2020): 1799-1809. |
| 11 | Anti-inflammatory | Krolikiewicz-Renimel, Isabelle, et al. "Protective effect of a Butea monosperma (Lam.) Taub. flowers extract against skin inflammation: antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities." Journal of ethnopharmacology 148.2 (2013): 537-543. Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Sindhia, V. R., and R. Bairwa. "Plant review: Butea monosperma." International journal of pharmaceutical and clinical research 2.2 (2010): 90-94. Kumari, Poonam, et al. "Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review." Current Pharmacology Reports 8.3 (2022): 188-204. Jain, Sourabh, and P. K. Dubey. "Butea monosperma (Lam.) Taub: Review on its chemistry, morphology, ethnomedical uses, phytochemistry and pharmacological activities." Journal of Drug Delivery and Therapeutics 13.4 (2023): 137-144. |
| 12 | Antioxidant and free radical scavenging activity | Talubmook, Chusri, and Nopparat Buddhakala. "Antioxidant and antidiabetic activities of flower extract from Butea monosperma (Lam.) Taub." GSTF International Journal on Bioformatics & Biotechnology (JBio) 2.1 (2012): 7. Kaur, Varinder, et al. "Butea monosperma (Lam.) Taub. Bark fractions protect against free radicals and induce apoptosis in MCF-7 breast cancer cells via cell-cycle arrest and ROS-mediated pathway." Drug and Chemical Toxicology 43.4 (2020): 398-408. Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Krolikiewicz-Renimel, Isabelle, et al. "Protective effect of a Butea monosperma (Lam.) Taub. flowers extract against skin inflammation: antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities." Journal of ethnopharmacology 148.2 (2013): 537-543. Sarkar, Bappa, et al. "In vitro free radical scavenging effect of Butea monosperma leaf extracts." Journal of Advanced Pharmacy Education & Research 5.3 (2015). Hasan, SM Raquibul, et al. "DPPH free radical scavenging activity of some Bangladeshi medicinal plants." J Med Plants Res 3.11 (2009): 875-879. |
| 13 | Anti-cancer | Hasan, SM Raquibul, et al. "DPPH free radical scavenging activity of some Bangladeshi medicinal plants." J Med Plants Res 3.11 (2009): 875-879. Rekha, J. Banu, and B. Jayakar. "Anti cancer activity of ethanolic extract of Leaves of Butea monosperma (Lam) Taub." Journal of Current Pharma Research 1.2 (2011): 106. Jain, Sourabh, and P. K. Dubey. "Butea monosperma (Lam.) Taub: Review on its chemistry, morphology, ethnomedical uses, phytochemistry and pharmacological activities." Journal of Drug Delivery and Therapeutics 13.4 (2023): 137-144. Ahmed, Fakhruddin Ali, and Humayun Kabir. "Ethnomedicinal value, phytochemical composition and bioactivity of Butea monosperma (Lam.) Taub." Jahangirnagar University Journal of Biological Sciences 4.2 (2015): 19-29. |
| 14 | Hepatoprotective effect | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Mishra, Ashish, Saket Verma, and Abhinav Prasoon Mishra. "A plant review: Butea monosperma (Lam.) Kuntze." Res. J. Pharm. Biol. Chem. Sci 3.1 (2012): 700-714. Kumari, Poonam, et al. "Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review." Current Pharmacology Reports 8.3 (2022): 188-204. Gupta, Arti, et al. "Evaluation of protective effect of Butea monosperma (lam.) Taub in experimental hepatotoxicity in rats." Journal of Pharmacology and Pharmacotherapeutics 3.2 (2012): 183-185. Jain, Sourabh, and P. K. Dubey. "Butea monosperma (Lam.) Taub: Review on its chemistry, morphology, ethnomedical uses, phytochemistry and pharmacological activities." Journal of Drug Delivery and Therapeutics 13.4 (2023): 137-144. |
| 15 | Nephroprotective activity | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Gupta, Arti, et al. "Evaluation of protective effect of Butea monosperma (lam.) Taub in experimental hepatotoxicity in rats." Journal of Pharmacology and Pharmacotherapeutics 3.2 (2012): 183-185. More, B. H., et al. "Ethnobotany & Ethanopharmacology of Butea Monosperma (Lam) Kuntze-A Compressive Review." Am J PharmTech Res 2.5 (2012): 138-159. Krolikiewicz-Renimel, Isabelle, et al. "Protective effect of a Butea monosperma (Lam.) Taub. flowers extract against skin inflammation: antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities." Journal of ethnopharmacology 148.2 (2013): 537-543. |
| 16 | Anti-diabetic | Sutariya, Brijesh Kantilal, and Madhusudan Natvarlal Saraf. "A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub." Journal of Applied Pharmaceutical Science 5.9 (2015): 159-166. Talubmook, Chusri, and Nopparat Buddhakala. "Antioxidant and antidiabetic activities of flower extract from Butea monosperma (Lam.) Taub." GSTF International Journal on Bioformatics & Biotechnology (JBio) 2.1 (2012): 7. Kumari, Poonam, et al. "Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review." Current Pharmacology Reports 8.3 (2022): 188-204. Mishra, Ashish, Saket Verma, and Abhinav Prasoon Mishra. "A plant review: Butea monosperma (Lam.) Kuntze." Res. J. Pharm. Biol. Chem. Sci 3.1 (2012): 700-714. Mahanthesh, M. T., et al. "Swiss ADME prediction of phytochemicals present in Butea monosperma (Lam.) Taub." Journal of Pharmacognosy and Phytochemistry 9.3 (2020): 1799-1809. |
| 17 | Anti-inflammatory | Krolikiewicz-Renimel, I., Michel, T., Destandau, E., Reddy, M., André, P., Elfakir, C., & Pichon, C. (2013). Protective effect of a Butea monosperma (Lam.) Taub. flowers extract against skin inflammation: antioxidant, anti-inflammatory and matrix metalloproteinases inhibitory activities. Journal of ethnopharmacology, 148(2), 537-543. Sutariya, B. K., & Saraf, M. N. (2015). A Comprehensive review on pharmacological profile of Butea monosperma (Lam.) Taub. Journal of Applied Pharmaceutical Science, 5(9), 159-166. Sindhia, V. R., & Bairwa, R. (2010). Plant review: Butea monosperma. International journal of pharmaceutical and clinical research, 2(2), 90-94. Kumari, P., Raina, K., Thakur, S., Sharma, R., Cruz-Martins, N., Kumar, P., ... & Chaudhary, A. (2022). Ethnobotany, phytochemistry and pharmacology of palash (butea monosperma (lam.) taub.): a systematic review. Current Pharmacology Reports, 8(3), 188-204. Jain, S., & Dubey, P. K. (2023). Butea monosperma (Lam.) Taub: Review on its chemistry, morphology, ethnomedical uses, phytochemistry and pharmacological activities. Journal of Drug Delivery and Therapeutics, 13(4), 137-144. |
Market Overview
Global End Use Market
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Distribution in IORA Countries
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Annual Consumption (in MT)
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