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Plant Details

Colebrookea oppositifolia Smith

BOTANICAL DETAILS OF PLANT

Synonyms

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Classification

Kingdom

Plantae

Subkingdom

Superdivision

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Division

Tracheophyta

Class

Magnoliopsida

Subclass

Order

Lamiales

Family

Lamiaceae

Genus

Colebrookea

Species

Colebrookea oppositifolia Sm.

Plant Description

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Habit/Life Form

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DISTRIBUTION OF SPECIES IN INDIA

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Plant Parts Used

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System of Medicine

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Intended Use

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Traditional Application


Phytochemical Details

# Phytochemical Constituents PUBCHEM CID References
1 Acteoside 5281800 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
2 Chrysin 5281607 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
3 Negletein 471719 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
4 Ladanein 3084066 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
5 Betulonic Acid 122844 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
6 Anisofolina A 21721971 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
7 Apigetrin 5280704 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
8 Forsythoside A 5281773 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
9 Alnustin 14138832 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
10 Flindulatin 5466138 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
11 Mosloflavone 471722 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.
12 Tanetin 10043097 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.

Pharmacological Details

# PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES REFERENCES
1 Antifertility Activity

Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                              

Yadav, Dinesh Kumar. "Pharmacognostical, phytochemical and pharmacological profile of Colebrookea oppositifolia Smith." Journal of Drug Delivery and Therapeutics 9.6-s (2019): 233-237.                                               

Kumar, Dinesh, et al. "Phytochemistry and Polypharmacological Potential of Colebrookea oppositifolia Smith." Current Topics in Medicinal Chemistry 23.5 (2023): 334-348.     

Yadav, Prity, et al. "Potential antifertility and antimicrobial activities of plants used in traditional medicines: A review." Journal of Pharmacognosy and Phytochemistry 12.2 (2023): 190-198.  

R Dias, Tania, et al. "Natural products as modulators of spermatogenesis: the search for a male contraceptive." Current Molecular Pharmacology 7.2 (2014): 154-166. 

2 Antiulcer Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                        
Ghaisas, M. M., et al. "Antiulcer activity of Colebrookea oppositifolia Sm." Research Journal of Pharmacology and Pharmacodynamics 2.1 (2010): 66-70. 

 Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.  

Kumar, Dinesh, et al. "Phytochemistry and Polypharmacological Potential of Colebrookea oppositifolia Smith." Current Topics in Medicinal Chemistry 23.5 (2023): 334-348.  

D’Souza, Ullas Prakash, Divya Jyothi, and Himanshu Joshi. "Evaluation of Antiulcer activity of Alcoholic stem extract of Epipremnum aureum (Linden andre) GS Bunting." Research Journal of Pharmacy and Technology 15.12 (2022): 5779-5784.
3 Hepatoprotective Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                             
Anwar, R., et al. "Effect of Colebrookea oppositifolia leaf extracts on cytochrome P450 and glutathione S-transferase activity in rats." Biologia (Pakistan) 68.1 (2022): 1-10.  

Kumar, Dinesh, et al. "Phytochemistry and Polypharmacological Potential of Colebrookea oppositifolia Smith." Current Topics in Medicinal Chemistry 23.5 (2023): 334-348. 

 Anwar, R., M. U. Khalil, and K. Ashiq. "Assessment of anti-hypertensive potential of Colebrookea oppositifolia by angiotensin-converting enzyme inhibition." Biologia (Pakistan) 68.2 (2022): 31-39.  

Ahmed, Toqeer, et al. "Assessment of antibacterial activity of Colebrookia oppositifolia against waterborne pathogens isolated from drinking water of the Pothwar region in Pakistan." Human and Ecological Risk Assessment 15.2 (2009): 401-415.

  Zhang, Meng-Qi, et al. "Hepatoprotective effects of total phenylethanoid glycosides from Acanthus ilicifolius L. against carbon tetrachloride-induced hepatotoxicity." Journal of ethnopharmacology 256 (2020): 112795. 

 Kumar, R. Vijay, et al. "Antioxidant-the maximum expressed activity among 63 medicinal plants." J Phyto Pharmacol 1.5 (2012): 1-13. 

 Perez Gutierrez, Rosa Martha, et al. "Effect of flavonoids from Prosthechea michuacana on carbon tetrachloride induced acute hepatotoxicity in mice." Pharmaceutical biology 49.11 (2011): 1121-1127. 

 Samal, Pradeep Kumar. "Assessment of Hepatoprotective Activity of Hibiscus vitifolius leaves in CCL4 induced hepatotoxic rats." Research Journal of Pharmacology and Pharmacodynamics 5.6 (2014): 313-316.  

Dhulap, Sivakami, Anita Mandhare, and Kashmira Deval. "Bio-evaluation studies of phytoconstituents-A review of the patents granted and filed by CSIR." Indian Journal of Natural Products and Resources (IJNPR)[Formerly Natural Product Radiance (NPR)] 13.4 (2023): 434-450.  

Yadav, Prity, et al. "Potential antifertility and antimicrobial activities of plants used in traditional medicines: A review." Journal of Pharmacognosy and Phytochemistry 12.2 (2023): 190-198.
4 Antimicrobial Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                       
Mahapatra, Santosh Kumar, et al. "Evaluation of antimicrobial potentiality of a flavonoid, isolated from the leaf of the plant Colebrookea Oppositifolia." Int. J. Biol. Pharm. Res 4 (2013): 225-230. 

 Ajaib, Muhammad, et al. "17. Phytochemical, antibacterial and antifungal activities of leaves and bark of Colebrookea oppositifolia: an ethnomedicinal plant." Pure and Applied Biology (PAB) 7.1 (2018): 138-151. 

 Shirsat, R. P., et al. "Two bioactive compounds from leaf extracts of Colebrookea oppositifolia Smith." Indian J. Applied & Pure Bio. Vol 29.1 (2014): 61-65.  

Ahmed, Toqeer, et al. "Assessment of antibacterial activity of Colebrookia oppositifolia against waterborne pathogens isolated from drinking water of the Pothwar region in Pakistan." Human and Ecological Risk Assessment 15.2 (2009): 401-415. 

 Sharma, Vipasha, Tarun Kumar, and Kamal Dev. "Effect of medicinal plant extracts on the antimicrobial activity of amoxyclave and erythromycin against E. coli and S. aureus." Int. J. Pharmaceut. Sci. Res 7 (2016): 4615-4625. 

Subba, Bimala, and Prakash Basnet. "Antimicrobial and antioxidant activity of some indigenous plants of Nepal." Journal of Pharmacognosy and Phytochemistry 3.1 (2014): 62-67.  

Anwar, R., et al. "Effect of Colebrookea oppositifolia leaf extracts on cytochrome P450 and glutathione S-transferase activity in rats." Biologia (Pakistan) 68.1 (2022): 1-10. 

 Mahato, R. B., and R. P. Chaudhary. "Ethnomedicinal study and antibacterial activities of selected plants of Palpa district, Nepal." Scientific world 3.3 (2005): 26-31.
5 Antioxidant Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                      
Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Characterization and anti-stroke activity of stem extract of Colebrookea oppositifolia Smith." Journal of Biologically Active Products from Nature 10.3 (2020): 250-263. 

 Shirsat, R. P., et al. "Two bioactive compounds from leaf extracts of Colebrookea oppositifolia Smith." Indian J. Applied & Pure Bio. Vol 29.1 (2014): 61-65.  

Pallab, K., et al. "In vitro–in vivo evaluation of cardioprotective effect of the leaf extract of Colebrookea oppositifolia Sm." J. Global Trend. Pharm. Sci 2 (2011): 310-324. 

 Subba, Bimala, and Prakash Basnet. "Antimicrobial and antioxidant activity of some indigenous plants of Nepal." Journal of Pharmacognosy and Phytochemistry 3.1 (2014): 62-67. 

Mahapatra, Santosh Kumar, et al. "Evaluation of antimicrobial potentiality of a flavonoid, isolated from the leaf of the plant Colebrookea Oppositifolia." Int. J. Biol. Pharm. Res 4 (2013): 225-230. 

Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Acteoside isolated from Colebrookea oppositifolia attenuates I/R brain injury in Wistar rats via modulation of HIF-1α, NF-κB, and VEGF pathways." Inflammopharmacology 29.5 (2021): 1565-1577. 

Sharma, Neha, et al. "Dereplication based strategy for rapid identification and isolation of a novel anti-inflammatory flavonoid by LCMS/MS from Colebrookea oppositifolia." ACS omega 6.45 (2021): 30241-30259. 

 Fatima, Maheen, et al. "Colebrookea Oppositifolia Anti Arthritic Potential Vs Methotrexate in Pristane Induced Rat Arthritis." Proceedings. Vol. 36. No. 1. 2022. 
6 Cardioprotective Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                             
Pallab, K., et al. "In vitro–in vivo evaluation of cardioprotective effect of the leaf extract of Colebrookea oppositifolia Sm." J. Global Trend. Pharm. Sci 2 (2011): 310-324.                                                                                                           
Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.  

Anwar, R., M. U. Khalil, and K. Ashiq. "Assessment of anti-hypertensive potential of Colebrookea oppositifolia by angiotensin-converting enzyme inhibition." Biologia (Pakistan) 68.2 (2022): 31-39.  

Yadav, Dinesh Kumar. "Pharmacognostical, phytochemical and pharmacological profile of Colebrookea oppositifolia Smith." Journal of Drug Delivery and Therapeutics 9.6-s (2019): 233-237.  

Fatima, Maheen, et al. "Colebrookea Oppositifolia Anti Arthritic Potential Vs Methotrexate in Pristane Induced Rat Arthritis." Proceedings. Vol. 36. No. 1. 2022.  

Arya, Vikrant, and Vivek Kumar Gupta. "Chemistry and pharmacology of plant cardioprotectives: a review." International Journal of Pharmaceutical Sciences and Research 2.5 (2011): 1156. 

 Bhat, Irshad Ul Haq, and Rajeev Bhat. "Quercetin: a bioactive compound imparting cardiovascular and neuroprotective benefits: scope for exploring fresh produce, their wastes, and by-products." Biology 10.7 (2021): 586. 
7 Anti-Inflammatory Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                               
Peron, Gregorio, et al. "Comprehensive characterization of secondary metabolites from colebrookea oppositifolia (Smith) leaves from nepal and assessment of cytotoxic effect and anti-Nf-κB and AP-1 activities in vitro." International Journal of Molecular Sciences 21.14 (2020): 4897.  

Sharma, Neha, et al. "Dereplication based strategy for rapid identification and isolation of a novel anti-inflammatory flavonoid by LCMS/MS from Colebrookea oppositifolia." ACS omega 6.45 (2021): 30241-30259.  

Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats." Journal of ethnopharmacology 223 (2018): 63-75.  

Yadav, Dinesh Kumar. "Pharmacognostical, phytochemical and pharmacological profile of Colebrookea oppositifolia Smith." Journal of Drug Delivery and Therapeutics 9.6-s (2019): 233-237. 

 Fatima, Maheen, et al. "Colebrookea Oppositifolia Anti Arthritic Potential Vs Methotrexate in Pristane Induced Rat Arthritis." Proceedings. Vol. 36. No. 1. 2022.  

Kumar, Dinesh, et al. "Phytochemistry and Polypharmacological Potential of Colebrookea oppositifolia Smith." Current Topics in Medicinal Chemistry 23.5 (2023): 334-348.  Anwar, R., et al. "Effect of Colebrookea oppositifolia leaf extracts on cytochrome P450 and glutathione S-transferase activity in rats." Biologia (Pakistan) 68.1 (2022): 1-10.  

Ganga, Rao B., Kiran P. Madhu, and Raju AD Vijaya. "Investigation of antioxidant and anti-inflammatory activity of leaves of Dalbergia paniculata (Roxb)." Asian Pacific journal of tropical medicine 5.6 (2012): 455-458. 

 Castro, Leandro A., et al. "Dereplication of Siparuna brasiliensis extract with in vivo anti-inflammatory activity." Natural Product Research 37.11 (2023): 1882-1887. 

 Song, Bocui, et al. "Gossypin: A flavonoid with diverse pharmacological effects." Chemical Biology & Drug Design 101.1 (2023): 131-137.
8 Wound Healing Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                     
Mahapatra, Santosh Kumar, et al. "Evaluation of antimicrobial potentiality of a flavonoid, isolated from the leaf of the plant Colebrookea Oppositifolia." Int. J. Biol. Pharm. Res 4 (2013): 225-230.  

Yadav, Dinesh Kumar. "Pharmacognostical, phytochemical and pharmacological profile of Colebrookea oppositifolia Smith." Journal of Drug Delivery and Therapeutics 9.6-s (2019): 233-237.  

Anwar, R., et al. "Effect of Colebrookea oppositifolia leaf extracts on cytochrome P450 and glutathione S-transferase activity in rats." Biologia (Pakistan) 68.1 (2022): 1-10. 

 Kumar, B., et al. "Ethnopharmacological approaches to wound healing—exploring medicinal plants of India." Journal of ethnopharmacology 114.2 (2007): 103-113.  

Shalu, Rani, et al. "Wound healing potential of medicinal plants with their screening models: a comprehensive review." Journal of Drug Delivery & Therapeutics 6.1 (2016): 56-66. 

Devi, S. Lakshmi, and Madhu C. Divakar. "Wound healing activity studies rats." Hygeia. JD Med 4.2 (2012): 87-94.
9 Anticonvulsant Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                   
Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Acteoside isolated from colebrookea oppositifolia smith attenuates epilepsy in mice via modulation of gamma-aminobutyric acid pathways." Neurotoxicity Research 38.4 (2020): 1010-1023. 

 Viswanatha, Gollapalle Lakshminarayanashastry, Marikunte V. Venkataranganna, and Nunna Bheema Lingeswara Prasad. "Ameliorative potential of Colebrookea oppositifolia methanolic root extract against experimental models of epilepsy: Possible role of GABA mediated mechanism." Biomedicine & Pharmacotherapy 90 (2017): 455-465.  

Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Anticonvulsant activity guided isolation of acteoside from methanolic root extracts of Colebrookea oppositifolia Smith." Journal of Biologically Active Products from Nature 9.5 (2019): 328-334.  

Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Methanolic stem extract of Colebrookea oppositifolia attenuates epilepsy in experimental animal models: possible role of GABA pathways." Journal of Biologically Active Products from Nature 10.1 (2020): 44-58. 

 Yadav, Dinesh Kumar. "Pharmacognostical, phytochemical and pharmacological profile of Colebrookea oppositifolia Smith." Journal of Drug Delivery and Therapeutics 9.6-s (2019): 233-237. 

 Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats." Journal of ethnopharmacology 223 (2018): 63-75.

  Sharma, Jyotsana, et al. "Ethnomedicinal plants used for treating epilepsy by indigenous communities of sub-Himalayan region of Uttarakhand, India." Journal of Ethnopharmacology 150.1 (2013): 353-370. 

 Gong, Guiyi, et al. "In vivo screening of xanthones from Garcinia oligantha identified oliganthin H as a novel natural inhibitor of convulsions." Journal of Natural Products 83.12 (2020): 3706-3716.
10 Anti-stroke Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.   

 Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Acteoside isolated from Colebrookea oppositifolia attenuates I/R brain injury in Wistar rats via modulation of HIF-1α, NF-κB, and VEGF pathways." Inflammopharmacology 29.5 (2021): 1565-1577. 

 Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Anticonvulsant activity guided isolation of acteoside from methanolic root extracts of Colebrookea oppositifolia Smith." Journal of Biologically Active Products from Nature 9.5 (2019): 328-334. 
11 Antihypertensive Activity Viswanatha, Gollapalle L., et al. "Traditional uses, phytochemistry, and ethnopharmacology of Colebrookea oppositifolia Smith: a mini-review." Advances in Traditional Medicine 21 (2021): 209-229.                                              
Anwar, R., M. U. Khalil, and K. Ashiq. "Assessment of anti-hypertensive potential of Colebrookea oppositifolia by angiotensin-converting enzyme inhibition." Biologia (Pakistan) 68.2 (2022): 31-39. 

 Pallab, K., et al. "In vitro–in vivo evaluation of cardioprotective effect of the leaf extract of Colebrookea oppositifolia Sm." J. Global Trend. Pharm. Sci 2 (2011): 310-324.

Khan, Rasel Ahmed, et al. "Anticancer effects of acteoside: Mechanistic insights and therapeutic status." European Journal of Pharmacology 916 (2022): 174699.    

Thuraisingam, Shobna, et al. "Development of nanoemulsion containing Centella asiatica crude extract as a promising drug delivery system for epilepsy treatment." Biointerface Res. Appl. Chem 13.17 (2022): 10-33263. 
 Amjad, Muhammad Shoaib, et al. "Ethnobotanical profiling of the medicinal flora of Kotli, Azad Jammu and Kashmir, Pakistan: Empirical reflections on multinomial logit specifications." Asian Pacific journal of tropical medicine 10.5 (2017): 503-514. 
12 Antihelmintic Activity Yadav DK, Pharmacognostical, Phytochemical and Pharmacological profile of Colebrookea oppositifolia Smith, Journal of Drug Delivery and Therapeutics. 2019; 9(6-s):233-237 http://dx.doi.org/10.22270/jddt.v9i6-s.3745 
                                                                                                                                        
Panda, Sujogya K., et al. "Antimicrobial, anthelmintic, and antiviral activity of plants traditionally used for treating infectious disease in the Similipal Biosphere Reserve, Odisha, India." Frontiers in pharmacology 8 (2017): 658. 

  Peron, Gregorio, et al. "Comprehensive characterization of secondary metabolites from colebrookea oppositifolia (Smith) leaves from nepal and assessment of cytotoxic effect and anti-Nf-κB and AP-1 activities in vitro." International Journal of Molecular Sciences 21.14 (2020): 4897. 
13 Antifungal Activity Yadav DK, Pharmacognostical, Phytochemical and Pharmacological profile of Colebrookea oppositifolia Smith, Journal of Drug Delivery and Therapeutics. 2019; 9(6-s):233-237 http://dx.doi.org/10.22270/jddt.v9i6-s.3745
                                                                                                                                                
Ali, Intzar, et al. "In vitro antifungal activities of amphotericin B in combination with acteoside, a phenylethanoid glycoside from Colebrookea oppositifolia." Journal of medical microbiology 60.9 (2011): 1326-1336.  

Ajaib, Muhammad, et al. "17. Phytochemical, antibacterial and antifungal activities of leaves and bark of Colebrookea oppositifolia: an ethnomedicinal plant." Pure and Applied Biology (PAB) 7.1 (2018): 138-151. 
 Yadav, Dinesh Kumar. "Pharmacognostical, phytochemical and pharmacological profile of Colebrookea oppositifolia Smith." Journal of Drug Delivery and Therapeutics 9.6-s (2019): 233-237. 
                                   
 Kumar, Dinesh, et al. "Phytochemistry and Polypharmacological Potential of Colebrookea oppositifolia Smith." Current Topics in Medicinal Chemistry 23.5 (2023): 334-348.  

Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Characterization and anti-stroke activity of stem extract of Colebrookea oppositifolia Smith." Journal of Biologically Active Products from Nature 10.3 (2020): 250-263. 

 Anwar, R., et al. "Effect of Colebrookea oppositifolia leaf extracts on cytochrome P450 and glutathione S-transferase activity in rats." Biologia (Pakistan) 68.1 (2022): 1-10.  

Sharma, Vipasha, Tarun Kumar, and Kamal Dev. "Effect of medicinal plant extracts on the antimicrobial activity of amoxyclave and erythromycin against E. coli and S. aureus." Int. J. Pharmaceut. Sci. Res 7 (2016): 4615-4625. 

 Subba, Bimala, and Prakash Basnet. "Antimicrobial and antioxidant activity of some indigenous plants of Nepal." Journal of Pharmacognosy and Phytochemistry 3.1 (2014): 62-67. 

 Panda, Sujogya K., et al. "Antimicrobial, anthelmintic, and antiviral activity of plants traditionally used for treating infectious disease in the Similipal Biosphere Reserve, Odisha, India." Frontiers in pharmacology 8 (2017): 658.

 Venkateshappa, S. M., and K. P. Sreenath. "Potential medicinal plants of Lamiaceae." American international journal of research in formal, applied and natural sciences 1.3 (2013): 82-87.  

Viswanatha, Gollapalle Lakshminarayanashastry, et al. "Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats." Journal of ethnopharmacology 223 (2018): 63-75.
14 Antinociceptive Activity Yadav DK, Pharmacognostical, Phytochemical and Pharmacological profile of Colebrookea oppositifolia Smith, Journal of Drug Delivery and Therapeutics. 2019; 9(6-s):233-237 http://dx.doi.org/10.22270/jddt.v9i6-s.3745                  

Ali, Intzar, et al. "In vitro antifungal activities of amphotericin B in combination with acteoside, a phenylethanoid glycoside from Colebrookea oppositifolia." Journal of medical microbiology 60.9 (2011): 1326-1336.  

Kumar, R. Vijay, et al. "Antioxidant-the maximum expressed activity among 63 medicinal plants." J Phyto Pharmacol 1.5 (2012): 1-13. 
15 Cytotoxic Activity Yadav DK, Pharmacognostical, Phytochemical and Pharmacological profile of Colebrookea oppositifolia Smith, Journal of Drug Delivery and Therapeutics. 2019; 9(6-s):233-237 http://dx.doi.org/10.22270/jddt.v9i6-s.3745 
                                                                                                                                    
Peron, Gregorio, et al. "Comprehensive characterization of secondary metabolites from colebrookea oppositifolia (Smith) leaves from nepal and assessment of cytotoxic effect and anti-Nf-κB and AP-1 activities in vitro." International Journal of Molecular Sciences 21.14 (2020): 4897.  
                       
Kumar, Dinesh, et al. "Phytochemistry and Polypharmacological Potential of Colebrookea oppositifolia Smith." Current Topics in Medicinal Chemistry 23.5 (2023): 334-348.  

Sharma, Neha, et al. "Dereplication based strategy for rapid identification and isolation of a novel anti-inflammatory flavonoid by LCMS/MS from Colebrookea oppositifolia." ACS omega 6.45 (2021): 30241-30259. 

 Panda, Sujogya K., et al. "Antimicrobial, anthelmintic, and antiviral activity of plants traditionally used for treating infectious disease in the Similipal Biosphere Reserve, Odisha, India." Frontiers in pharmacology 8 (2017): 658. 

 Bahadur, Saraj, et al. "Authentication of the therapeutic Lamiaceae taxa by using pollen traits observed under scanning electron microscopy." Microscopy Research and Technique 85.6 (2022): 2026-2044. 

Market Overview

Global End Use Market

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Available Global Market

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Global Manufacturer Extract

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Distribution in IORA Countries

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Trade Data

Source Supply

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Trade Name

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Annual Consumption (in MT)

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Adulterant/Substitute

CULTIVARS AND VARIETIES