- Home
- Plant Details
Hypericum perforatum L
BOTANICAL DETAILS OF PLANT
Synonyms
--
Classification
Kingdom
Plantae
Subkingdom
Superdivision
--
Division
Streptophyta
Class
Equisetopsida
Subclass
Magnoliidae
Order
Malpighiales
Family
Hypericaceae
Genus
Hypericum
Species
Hypericum perforatum
Plant Description
-
Habit/Life Form
--
DISTRIBUTION OF SPECIES IN INDIA
-
Plant Parts Used
-
System of Medicine
-
Intended Use
-
Traditional Application
Phytochemical Details
| # | Phytochemical Constituents | PUBCHEM CID | References |
|---|---|---|---|
| 1 | Hyperforin | 441298 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 2 | Hypericin | 3663 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 3 | Pseudohypericin | 4978 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 4 | Isohypericin | 136161635 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 5 | Protohypericin | 164660 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 6 | Protopseudohypericin | 171335 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 7 | Cyclopseudohypericin | 274079362 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 8 | Hyperoside | 5281643 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 9 | Biapigenin | 10414856 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 10 | Adhyperforin | 9963735 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 11 | Kielcorin | 13834128 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 12 | Norathyriol | 5281656 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 13 | Catechin | 9064 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 14 | Procyanidin | 107876 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 15 | Epicatechin | 72276 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
| 16 | Amentoflavone | 5281600 | Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. |
Pharmacological Details
| # | PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES | REFERENCES |
|---|---|---|
| 1 | Antibacterial Activity | Saddiqe, Zeb, Ismat Naeem, and Alya Maimoona. "A review of the antibacterial activity of Hypericum perforatum L." Journal of ethnopharmacology 131.3 (2010): 511-521. Okmen, Gulten, and Neslihan Balpınar. "The biological activities of Hypericum perforatum L." African Journal of Traditional, Complementary and Alternative Medicines 14.1 (2017): 213-218.
Reichling, J., A. Weseler, and R. Saller. "A current review of the antimicrobial activity of Hypericum perforatum L." Pharmacopsychiatry 34.Sup. 1 (2001): 116-118.
Alahmad, Abdalrahim, et al. "Green synthesis of silver nanoparticles using Hypericum perforatum L. aqueous extract with the evaluation of its antibacterial activity against clinical and food pathogens." Pharmaceutics 14.5 (2022): 1104. Milosevic, Tanja, S. L. A. V. I. C. A. Solujic-Sukdolak, and Slobodan Sukdolak. "In vitro study of ethanolic extract of Hypericum perforatum L. on growth and sporulation of some bacteria and fungi." Turkish Journal of Biology 31.4 (2007): 237-241.
Özkan, Esra EROĞLU, Berna ÖZBEK Çelik, and M. Afife. "Antimicrobial activities of five endemic Hypericum species from Anatolia compared with Hypericum perforatum." J. Res. Pharm 23 (2019): 114-119. Jonuškienė, Ilona, et al. "The Influence of Phytohormones on Antioxidative and Antibacterial Activities in Callus Cultures of Hypericum perforatum L." Agriculture 13.8 (2023): 1543.
Ozgen, Arzu, et al. "Characterization of biosynthesized silver nanoparticles using Hypericum perforatum leaf and determination of their antibacterial activity." Med. Sci 8.3 (2019): 503-507.
Gitea, D. A. N. I. E. L. A., et al. "Green synthesis of silver nanoparticles using Hypericum perforatum L. extract and evaluation of their antibacterial activity." Rev. Chim 71 (2020): 273-279.
Mutlu, Betül, Fatih Erci, and Rabia Çakir Koç. "Production of alginate films containing Hypericum perforatum extract as an antibacterial and antioxidant wound dressing material." Journal of Bioactive and Compatible Polymers 37.2 (2022): 134-148.
Rančić, Ana, et al. "Chemical composition and antimicrobial activities of essential oils of Myrrhis odorata (L.) Scop, Hypericum perforatum L and Helichrysum arenarium (L.) Moench." Journal of Essential Oil Research 17.3 (2005): 341-345. Jesionek, Wioleta, et al. "TLC-Direct Bioautography as a Bioassay Guided Method for Investigation of Antibacterial Compounds in Hypericum perforatum L." Journal of AOAC International 98.4 (2015): 1013-1020. Doğan, Şule, et al. "Anti-quorum sensing and anti-biofilm activities of Hypericum perforatum extracts against Pseudomonas aeruginosa." Journal of ethnopharmacology 235 (2019): 293-300. Nur Parin, Fatma, and Sinan Deveci. "Production and Characterization of Bio‐based Sponges Reinforced with Hypericum perforatum oil (St. John′ s Wort Oil) via Pickering Emulsions for Wound Healing Applications." ChemistrySelect 8.5 (2023): e202203692. |
| 2 | Neuroprotective Activity | Oliveira, Ana I., et al. "Neuroprotective activity of Hypericum perforatum and its major components." Frontiers in plant science 7 (2016): 1004. Tusevski, O., et al. "Phenolic profile and biological activity of Hypericum perforatum L.: Can roots be considered as a new source of natural compounds?." South African Journal of Botany 117 (2018): 301-310. Silva, Bruno, et al. "Quercetin, kaempferol and biapigenin from Hypericum perforatum are neuroprotective against excitotoxic insults." Neurotoxicity research 13 (2008): 265-279. Oliveira, Ana Isabel, et al. "Development, characterization, antioxidant and hepatoprotective properties of poly (Ɛ-caprolactone) nanoparticles loaded with a neuroprotective fraction of Hypericum perforatum." International journal of biological macromolecules 110 (2018): 185-196. Ji, Yuan-yuan, et al. "Chemical characterization, neuroprotective, antimicrobial and enzyme inhibitory activities of Hypericum volatile oils." Industrial Crops and Products 172 (2021): 113991. Shrivastava, Mansi, and L. Dwivedi. "Therapeutic potential of Hypericum perforatum: a review." Int J Pharm Sci Res 6.12 (2015): 4982-4988. Budantsev, Andrey L., et al. "Biological activity of Hypericum perforatum L.(Hypericaceae): a review." Pharmacy & Pharmacology 9.1 (2021): 17-31. Yang, Ling, et al. "Phenolic constituents with neuroprotective activities from Hypericum wightianum." Phytochemistry 165 (2019): 112049. Prakash, D. Jaya, S. Arulkumar, and M. Sabesan. "Effect of nanohypericum (Hypericum perforatum gold nanoparticles) treatment on restraint stressinduced behavioral and biochemical alteration in male albino mice." Pharmacognosy research 2.6 (2010): 330. Kumar, G. Phani, and Farhath Khanum. "Neuroprotective potential of phytochemicals." Pharmacognosy reviews 6.12 (2012): 81. Munoz, Maria, et al. "SNP-mediated neuroprotection under glucose deprivation is enhanced by hypericum perforatum." CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders) 11.2 (2012): 162-173. Guo, Yi, et al. "Hyperforatins L–U: Prenylated acylphloroglucinols with a terminal double bond from Hypericum perforatum L.(St John's Wort)." Phytochemistry 164 (2019): 41-49. Cao, Zheng, et al. "Hypericum perforatum extract attenuates behavioral, biochemical, and neurochemical abnormalities in aluminum chloride-induced Alzheimer’s disease rats." Biomedicine & pharmacotherapy 91 (2017): 931-937. Fumia, Angelo, et al. "Role of nutraceuticals on neurodegenerative diseases: Neuroprotective and immunomodulant activity." Natural Product Research 36.22 (2022): 5916-5933. Lou, Huayong, et al. "Polycyclic polyprenylated acylphloroglucinols with acetylcholinesterase inhibitory activities from Hypericum perforatum." Fitoterapia 143 (2020): 104550. Akkuş, Rabia Yaren, et al. "Neuroprotective effect of Hypericum perforatum extract against aluminum-maltolate induced toxicity in SH-SY5Y cells." International Journal of Science Letters 4.2 (2022): 277-291. |
| 3 | Antioxident Activity | Sánchez-Muniz, Francisco J., et al. "Antioxidant activity of Hypericum perforatum L. extract in enriched n-3 PUFA pork meat systems during chilled storage." Food Research International 48.2 (2012): 909-915. Zou, Yanping, Yanhua Lu, and Dongzhi Wei. "Antioxidant activity of a flavonoid-rich extract of Hypericum perforatum L. in vitro." Journal of Agricultural and Food Chemistry 52.16 (2004): 5032-5039. Gioti, Eleni M., et al. "Antioxidant activity and bioactive components of the aerial parts of Hypericum perforatum L. from Epirus, Greece." Food Chemistry 117.3 (2009): 398-404. Brankiewicz, Aleksandra, et al. "Cytotoxic and Antioxidant Activity of Hypericum perforatum L. Extracts against Human Melanoma Cells from Different Stages of Cancer Progression, Cultured under Normoxia and Hypoxia." Molecules 28.3 (2023): 1509. Heinrich, Miriam, et al. "Lipid and phenolic constituents from seeds of Hypericum perforatum L. and Hypericum tetrapterum Fr. and their antioxidant activity." Chemistry & Biodiversity 14.8 (2017): e1700100. Franchi, Gian Gabriele, et al. "Composition and antioxidant activity in vitro of different St. John’s Wort (Hypericum perforatum L.) extracts." Journal of Medicinal Plants Research 5.17 (2011): 4349-4353. Raziq, Niala, et al. "Correlation of the antioxidant capacity with the phenolic contents of Hypericum monogynum and Hypericum perforatum." African Journal of Pharmacy and Pharmacology 5.16 (2011): 1872-1876. Okmen, Gulten, and Neslihan Balpınar. "The biological activities of Hypericum perforatum L." African Journal of Traditional, Complementary and Alternative Medicines 14.1 (2017): 213-218. Morshedloo, M. R., et al. "Essential oil composition, total phenol compounds and antioxidant activity of Hypericum perforatum L. extract collected from North of Iran." Journal of Medicinal Plants 11.41 (2012): 218-226. Fathi, Hamed, and Mohammad Ali Ebrahimzadeh. "Antioxidant and free radical scavenging activities of Hypericum perforatum L.(st. John’s wort)." International Journal of Forest, Soil and Erosion (IJFSE) 3.2 (2013): 68-72. Benedı́, Juana, et al. "Antioxidant properties and protective effects of a standardized extract of Hypericum perforatum on hydrogen peroxide-induced oxidative damage in PC12 cells." Life sciences 75.10 (2004): 1263-1276. Conforti, Filomena, et al. "Comparative chemical composition and variability of biological activity of methanolic extracts from Hypericum perforatum L." Natural product research 19.3 (2005): 295-303. Stojanovic, G., A. Dordevic, and A. Smelcerovic. "Do other Hypericum species have medical potential as St. John's wort (Hypericum perforatum)?." Current medicinal chemistry 20.18 (2013): 2273-2295. Altun, M. Levent, et al. "Assessment of cholinesterase and tyrosinase inhibitory and antioxidant effects of Hypericum perforatum L.(St. John's wort)." Industrial Crops and Products 43 (2013): 87-92. Menichini, Giulio, et al. "Hypericum perforatum L. subsp. perforatum induces inhibition of free radicals and enhanced phototoxicity in human melanoma cells under ultraviolet light." Cell Proliferation 46.2 (2013): 193-202. Zou, Yanping, Yanhua Lu, and Dongzhi Wei. "Hypocholesterolemic effects of a flavonoid-rich extract of Hypericum perforatum L. in rats fed a cholesterol-rich diet." Journal of agricultural and food chemistry 53.7 (2005): 2462-2466. |
| 4 | Wound healing Activity | Öztürk, Nilgün, Seval Korkmaz, and Yusuf Öztürk. "Wound-healing activity of St. John's Wort (Hypericum perforatum L.) on chicken embryonic fibroblasts." Journal of ethnopharmacology 111.1 (2007): 33-39. Süntar, Ipek Peşin, et al. "Investigations on the in vivo wound healing potential of Hypericum perforatum L." Journal of ethnopharmacology 127.2 (2010): 468-477. Saddiqe, Zeb, Ismat Naeem, and Alya Maimoona. "A review of the antibacterial activity of Hypericum perforatum L." Journal of ethnopharmacology 131.3 (2010): 511-521. Süntar, Ipek, et al. "A novel wound healing ointment: a formulation of Hypericum perforatum oil and sage and oregano essential oils based on traditional Turkish knowledge." Journal of ethnopharmacology 134.1 (2011): 89-96. Castro, Fabiene CB, et al. "Effects of microcurrent application alone or in combination with topical Hypericum perforatum L. and Arnica montana L. on surgically induced wound healing in Wistar rats." Homeopathy 101.03 (2012): 147-153. Guleken, Zozan, et al. "Spectrochemical and biochemical assay comparison study of the healing effect of the Aloe vera and Hypericum perforatum loaded nanofiber dressings on diabetic wound." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 254 (2021): 119639. Yalcınkaya, Esin, et al. "Efficiency of hypericum perforatum, povidone iodine, tincture benzoin and tretinoin on wound healing." Food and Chemical Toxicology 166 (2022): 113209. Hemmati, A. A., I. Rashidi, and M. Jafari. "Promotion of wound healing by Hypericum perforatum extract in rabbit." Jundishapur Journal of Natural Pharmaceutical Products 2.2 (2007): 78-86. Altıparmak, Mehmet, et al. "Skin wound healing properties of Hypericum perforatum, Liquidambar orientalis, and propolis mixtures." European Journal of Plastic Surgery 42 (2019): 489-494. Nur Parin, Fatma, and Sinan Deveci. "Production and Characterization of Bio‐based Sponges Reinforced with Hypericum perforatum oil (St. John′ s Wort Oil) via Pickering Emulsions for Wound Healing Applications." ChemistrySelect 8.5 (2023): e202203692. Kotsiou, A., et al. "Pleiotropic activity of Hypericum perforatum L." Fitoterapia 66 (1995): 43-68. Bölgen, Nimet, et al. "Development of Hypericum perforatum oil incorporated antimicrobial and antioxidant chitosan cryogel as a wound dressing material." International Journal of Biological Macromolecules 161 (2020): 1581-1590. Budantsev, Andrey L., et al. "Biological activity of Hypericum perforatum L.(Hypericaceae): a review." Pharmacy & Pharmacology 9.1 (2021): 17-31. Ali, Mohamed, et al. "An in vivo study of Hypericum perforatum in a niosomal topical drug delivery system." Drug delivery 25.1 (2018): 417-425. Kotsiou, A., and C. Tesseromatis. "Hypericum perforatum for experimental skin burns treatment in rats in comparison to nitrofurazone." J. Med. Plants 8 (2020): 227-231. Çobanoğlu, Asuman, and Merdiye Şendir. "The effect of hypericum perforatum oil on the healing process in the care of episiotomy wounds: A randomized controlled trial." European Journal of Integrative Medicine 34 (2020): 100995. |
| 5 | Anticancer Activity | Eroglu, Erdal, and Seyda Nur Girgin. "A unique phenolic extraction method from olive oil macerate of Hypericum perforatum using DMSO: Assessment of in vitro anticancer activity, LC-MS/MS profile, total phenolic content and antioxidant capacity." South African Journal of Botany 139 (2021): 6-11. Gönenç, TUBA MERT, et al. "Hypericum perforatum L. An overview of the anticancer potencies of the specimens collected from different ecological environments." Pak. J. Bot 52.3 (2020): 1003-1010. Kirakosyan, Ara, et al. "The production of hypericins and hyperforin by in vitro cultures of St. John's wort (Hypericum perforatum)." Biotechnology and applied biochemistry 39.1 (2004): 71-81. Amjadi, Issa, et al. "Antiproliferative effects of free and encapsulated Hypericum perforatum L. extract and its potential interaction with doxorubicin for esophageal squamous cell carcinoma." Journal of pharmacopuncture 22.2 (2019): 102. Menichini, Giulio, et al. "Hypericum perforatum L. subsp. perforatum induces inhibition of free radicals and enhanced phototoxicity in human melanoma cells under ultraviolet light." Cell Proliferation 46.2 (2013): 193-202. Alavi Dana, Seyyed MM, et al. "Anti-cancer Potential of Hypericum spp. with Focus on Hypericum Perforatum: A Review of the Literature." Current Traditional Medicine 9.4 (2023): 87-104. Brito, Lavínia de C., Ana Luiza Rangel Berenger, and Maria Raquel Figueiredo. "An overview of anticancer activity of Garcinia and Hypericum." Food and Chemical Toxicology 109 (2017): 847-862. Şengün, Dilara Nur, et al. "Evaluation of the chemopreventive effects of Hypericum perforatum L on DMBA-applied rat oral mucosa." Archives of Oral Biology 127 (2021): 105139. Cui, Xi-Hua, Hosakatte Niranjana Murthy, and Kee-Yoeup Paek. "Production of adventitious root biomass and bioactive compounds from Hypericum perforatum L. through large scale bioreactor cultures." Production of biomass and bioactive compounds using bioreactor technology (2014): 251-283. Alahmad, Abdalrahim, et al. "Green synthesis of silver nanoparticles using Hypericum perforatum L. aqueous extract with the evaluation of its antibacterial activity against clinical and food pathogens." Pharmaceutics 14.5 (2022): 1104. Choudhary, Neeraj, et al. "Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application." Phytomedicine (2022): 154356. Cai, Fanfan, et al. "Combination of integrated expanded bed adsorption chromatography and countercurrent chromatography for the direct extraction and purification of pseudohypericin and hypericin from St. John's wort (Hypericum perforatum L.)." Journal of separation science 38.15 (2015): 2588-2596. |
| 6 | Anxiolytic Activity | Vandenbogaerde, A., et al. "Evidence that total extract of Hypericum perforatum affects exploratory behavior and exerts anxiolytic effects in rats." Pharmacology Biochemistry and Behavior 65.4 (2000): 627-633. Chatterjee, Sh S., et al. "Antidepressant activity of Hypericum perforatum and hyperforin: the neglected possibility." Pharmacopsychiatry 31.S 1 (1998): 7-15. Crupi, Rosalia, et al. "Hypericum perforatum treatment: effect on behaviour and neurogenesis in a chronic stress model in mice." BMC complementary and alternative medicine 11 (2011): 1-10. Kumar, Vikas, et al. "Brain neurotransmitter receptor binding and nootropic studies on Indian Hypericum perforatum Linn." Phytotherapy Research 16.3 (2002): 210-216. Beijamini, Vanessa, and Roberto Andreatini. "Effects of Hypericum perforatum and paroxetine in the mouse defense test battery." Pharmacology Biochemistry and Behavior 74.4 (2003): 1015-1024. Barnes, Joanne, Linda A. Anderson, and J. David Phillipson. "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties." Journal of pharmacy and pharmacology 53.5 (2001): 583-600. Husain, G. M., et al. "Antiaggressive activity of standardized extract of Indian Hypericum perforatum L." Pharmacologyonlne 1 (2009): 432-44. Velingkar, Vinay S., Girdharilal L. Gupta, and Namita B. Hegde. "A current update on phytochemistry, pharmacology and herb–drug interactions of Hypericum perforatum." Phytochemistry Reviews 16 (2017): 725-744. Campos, Leandro V., et al. "Rats treated with Hypericum perforatum during pregnancy generate offspring with behavioral changes in adulthood." Revista Brasileira de Farmacognosia 27 (2017): 361-368. Zanoli, P., et al. "Pharmacological activity of hyperforin acetate in rats." Behavioural pharmacology 13.8 (2002): 645-651. |
| 7 | Hypolipidemic Activity | Hernández-Saavedra, Diego, et al. "Phytochemical characterization and effect of Calendula officinalis, Hypericum perforatum, and Salvia officinalis infusions on obesity-associated cardiovascular risk." Medicinal Chemistry Research 25 (2016): 163-172. Hamed, Zena S., et al. "Effects of Hypericum perforatum on serum lipid vascular systems in mice." Iraqi Journal of Veterinary Sciences 36.2 (2022): 525-530. Zou, Yanping, Yanhua Lu, and Dongzhi Wei. "Hypocholesterolemic effects of a flavonoid-rich extract of Hypericum perforatum L. in rats fed a cholesterol-rich diet." Journal of agricultural and food chemistry 53.7 (2005): 2462-2466. Pérez‐Ramírez, Iza F., et al. "Mechanisms associated with the effect of Hypericum perforatum and Smilax cordifolia aqueous extracts on hepatic steatosis in obese rats: a lipidomic approach." European Journal of Lipid Science and Technology 121.2 (2019): 1800403. Kabiri, Najmeh, Sedigheh Asgary, and Mahbubeh Setorki. "The effects of concurrent hydroalcoholic extract of Amaranthus caudatus L. and Hypericum perforatum L. of fatty streak formation in hypercholesterolemic animals." African Journal of Pharmacy and Pharmacology 5.16 (2011): 1911-1919. Velingkar, Vinay S., Girdharilal L. Gupta, and Namita B. Hegde. "A current update on phytochemistry, pharmacology and herb–drug interactions of Hypericum perforatum." Phytochemistry Reviews 16 (2017): 725-744. Habibi Asl, B., et al. "Comparison of the therapeutic effects of total extract of Hypericum perforatum and calcific and magnesic sulfate mineral water on lipid profile of Hyperlipidemic rats." J Fac Pharm, Tabriz U Med Sci 4 (2008): 23-9. Aslanabadi, Naser, et al. "Hypolipidemic activity of a natural mineral water rich in calcium, magnesium, and bicarbonate in hyperlipidemic adults." Advanced pharmaceutical bulletin 4.3 (2014): 303. Moghadam, MohammadHassan Ghosian, et al. "The effect of oral administration of Hypericum perforatum on serum glucose and lipids, hepatic enzymes and lipid peroxidation in streptozotocin-induced diabetic rats." Galen Medical Journal 6.4 (2017): 319-329. |
Market Overview
Global End Use Market
--
Available Global Market
--
Global Manufacturer Extract
---
Distribution in IORA Countries
--
Trade Data
Source Supply
-
Trade Name
-
Annual Consumption (in MT)
-