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Plant Details

Holoptelea integrifolia

BOTANICAL DETAILS OF PLANT

Synonyms

--

Classification

Kingdom

Plantae

Subkingdom

Superdivision

--

Division

Streptophyta

Class

Equisetopsida

Subclass

Magnoliidae

Order

Rosales

Family

Ulmaceae

Genus

Holoptelea

Species

Holoptelea integrifolia

Plant Description

-

Habit/Life Form

--

DISTRIBUTION OF SPECIES IN INDIA

-

Plant Parts Used

-

System of Medicine

-

Intended Use

-

Traditional Application


Phytochemical Details

# Phytochemical Constituents PUBCHEM CID References
1 Hexacosanol 68171 Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213
2 Octacosanol 68406 Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213
3 Friedlin 3684865 Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213
4 Epifriedelinol 119242 Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213
5 1, 4-Napthalenedione 129724840 Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213
6 Botulin 135297362 Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213
7 Betulinic Acid 64971 Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213

Pharmacological Details

# PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES REFERENCES
1 Antibacterial Activity

Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213.                   

Kumar, Vijay, et al. "Green synthesis of silver nanoparticles using leaf extract of Holoptelea integrifolia and preliminary investigation of its antioxidant, anti-inflammatory, antidiabetic and antibacterial activities." Journal of Environmental Chemical Engineering 7.3 (2019): 103094.                           

Reddy, Boreddy Srinivas, et al. "Evaluation of antimicrobial, antioxidant and wound-healing potentials of Holoptelea integrifolia." Journal of Ethnopharmacology 115.2 (2008): 249-256.                                                      

 Sharma, M. C., et al. "Antimicrobial activity of aqueous extract of Holoptelea integrifolia (Roxb.) leaves: An in vitro study." Pharmacologyonline 1 (2009): 155-159.   

                                                                            

Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                       

Solanki, Pooja, Dhruv Pandya, and Bharat Maitreya. "Antimicrobial activity of methanolic & aqueous extracts of leaves & young stem bark of Holoptelea integrifolia L." Int. J. Bot. Stud 5 (2020): 123-127.                                     

Munawar, T. Mohammad, D. Muralidhara Rao, and P. Subramanyam. "Antibacterial, antioxidant and anti-inflammatory potential of the different extracts of Holoptelia integrifolia." Int. J. Eng. Adv. Technol 9 (2019): 5234-5240.   

                                                                                                                                  

Vinod, N. V., et al. "Inhibition of beta-lactamase by 1, 4-naphthalenedione from the plant Holoptelea integrifolia." Applied biochemistry and biotechnology 160 (2010): 1752-1759.                                                                    

Sharma, Uma, et al. "Antibacterial activity of some medicinal plants of family Lamiaceae from Braj region." Glob J Res Med Plants 1 (2013): 72-6.   

2 Antifungal Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213.                            

  Ishnava, Kalpesh B., K. H. Chauhan, and C. A. Bhatt. "Screening of antifungal activity of various plant leaves extracts from Indian plants." Archives of Phytopathology and Plant Protection 45.2 (2012): 152-160.                              
 Sahoo, Santosk K., Vivek K. Yadav, and A. R. Saxena. "Antifungal properties of Holoptelea integrifolia (Roxb.) Planch." Annals of Plant Protection Sciences 18.2 (2010): 438-442.                                                                                         
Singh, Meenakshi, et al. "Antimicrobial screening of ethnobotanically important stem bark of medicinal plants." Pharmacognosy research 2.4 (2010): 254.                                                                                                                             
Bhuvad Sushama, B., and K. Nishteswar. "Ayurvedic and Ethno–botanical perspectives of chirabilva (Holoptelea Integrifolia Planch)." Int Ayurvedic Med J 1 (2013): 1-8.                                                                                                                  
War, Ishfaq Rashid, et al. "Antifungal activity of Cassia fistula Linn. against some pathogenic fungi." International Journal of Phytomedicine 6.2 (2014): 182.                                                                                                                                       
Kumar, R. Bharath, and B. Suryanarayana. "Antimicrobial screening of some selected tribal medicinal plants from Sriharikota Island, Andhra Pradesh, India." Ethnobotanical Leaflets 2008.1 (2008): 171.                               
Thippeswamy, Sreerangegowda, Devihalli Chikkaiah Mohana, and Kiragandur Manjunath. "Screening of in vitro antifungal activity of some indian medicinal plants against Candida albicans and Cryptococcus neoformans." International Journal of Current Research 4.3 (2012): 37-42.
3 Analgesic Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213.                                        

 Rizwani, Ghazala Hafeez, et al. "Analgesic activity of various extracts of Holoptelea integrifolia (Roxb.) Planch leaves." Pak. J. Pharm. Sci 25.3 (2012): 629-632.                                                                                                                                     
Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                                      
Ghazala Hafeez, Rizwani, et al. "Analgesic activity of various extracts of Holoptelea integrifolia [Roxb] Planch leaves." (2012): 629-632.                

Hasan, Md Nazmul, et al. "Preliminary phytochemical screening, toxicity, antihyperglycemic and analgesic activity studies with Curcuma longa leaves." World Journal of Pharmacy and Pharmaceutical Sciences 3.9 (2014): 81-91.                                                                                                                                       

 Zahid, Affan, Ghazala H. Rizwani, and Hina Zahid. "Anti-nociceptive and anti-inflammatory activities of Holoptelea intrigofolia (Roxb.) planch fruit extract on laboratory animals." African Journal of Pharmacy and Pharmacology 9.36 (2015): 886-892.                                                                                 

Le, Ha Minh, et al. "Phytochemicals, Antiinflammatory, and Analgesic Effects of the Ethanol Extract From the Leaves of Premna Flavescens Wall. ex CB Clarke." Natural Product Communications 17.7 (2022): 1934578X221112812.
4 Antioxidant Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213.                                      

 Reddy, Boreddy Srinivas, et al. "Evaluation of antimicrobial, antioxidant and wound-healing potentials of Holoptelea integrifolia." Journal of Ethnopharmacology 115.2 (2008): 249-256.                                                   
Saraswathy, A., S. Nandini Devi, and D. Ramasamy. "Antioxidant, heavy metals and elemental analysis of Holoptelea integrifolia Planch." Indian Journal of Pharmaceutical Sciences 70.5 (2008): 683.                                      
 Kumar, Vijay, et al. "Green synthesis of silver nanoparticles using leaf extract of Holoptelea integrifolia and preliminary investigation of its antioxidant, anti-inflammatory, antidiabetic and antibacterial activities." Journal of Environmental Chemical Engineering 7.3 (2019): 103094.                   

Kumar, Vijay, et al. "Phytochemical, analytical and medicinal studies of holoptelea integrifolia roxb. Planch-a review." Current Traditional Medicine 5.4 (2019): 270-277.                                                                                        
Dixit, Prateek, Mahesh Pal, and Dalip Upreti. "Comparative studies on the analytical and antioxidant activities of the medicinally important stem bark of Holoptelea integrifolia." JPC-Journal of Planar Chromatography-Modern TLC 27.3 (2014): 162-165. 
                                                                                               
Kumar, Dinesh, et al. "A mini review on chemistry and biology of Holoptelea integrifolia Roxb. Planch (Ulmaceae)." Asian Pacific Journal of Tropical Biomedicine 2.2 (2012): S1200-S1205.                                                
Munawar, T. Mohammad, D. Muralidhara Rao, and P. Subramanyam. "Antibacterial, antioxidant and anti-inflammatory potential of the different extracts of Holoptelia integrifolia." Int. J. Eng. Adv. Technol 9 (2019): 5234-5240. 
                                                                                                                                      
Pratap, Harendra, et al. "A study on anti-inflammatory activity of stem bark extract of Holoptelea integrifolia." Research Journal of Pharmacy and Technology 15.1 (2022): 77-81.                                                                                   
Rizwani, Ghazala Hafeez, et al. "Analgesic activity of various extracts of Holoptelea integrifolia (Roxb.) Planch leaves." Pak. J. Pharm. Sci 25.3 (2012): 629-632.                                                                                                                              
 Kumar, Vijay, et al. "High resolution GC/MS analysis of the Holoptelea integrifoli's leaves and their medicinal qualities." Biocatalysis and Agricultural Biotechnology 22 (2019): 101405.
5 Anti-Inflammatory Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213.                        

Kumar, Vijay, et al. "Green synthesis of silver nanoparticles using leaf extract of Holoptelea integrifolia and preliminary investigation of its antioxidant, anti-inflammatory, antidiabetic and antibacterial activities." Journal of Environmental Chemical Engineering 7.3 (2019): 103094.        

Pratap, Harendra, et al. "A study on anti-inflammatory activity of stem bark extract of Holoptelea integrifolia." Research Journal of Pharmacy and Technology 15.1 (2022): 77-81.                                                                                      
Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                               
 Aadesh, Upadhyay. "Anti-inflammatory evaluation of ethanolic extract of leaves of Holoptelea integrifolia, Planch." Annals of Biological Research 1.2 (2010): 185-195.                                                                                                                
Bhuvad Sushama, B., and K. Nishteswar. "Ayurvedic and Ethno–botanical perspectives of chirabilva (Holoptelea Integrifolia Planch)." Int Ayurvedic Med J 1 (2013): 1-8.                                                                                                            
Chinna, Eswaraiah, and Amgoth Srinivas Nayak. "In vitro anti-inflammatory activity of various extracts of leaf and bark of Holoptelia integrifolia Planch." International Journal of Pharmaceutical Sciences and Research (IJPSR) 5.7 (2014): 2987-2990. 
                                                                                     
Reddy, Boreddy Srinivas, et al. "Evaluation of antimicrobial, antioxidant and wound-healing potentials of Holoptelea integrifolia." Journal of Ethnopharmacology 115.2 (2008): 249-256.                                                     
Somwong, K., et al. "Bark extracts of Holoptelea integrifolia and their bioactive components on canine demodicosis through anti-inflammation on COX-2 and iNOS inhibition." Planta Medica 88.15 (2022): 1544-1544.    

Sharma, Jyoti, et al. "Study of antidiabetic activity of the stem bark extract of Holoptelea integrifolia (Roxb.)." Research Journal of Pharmacology and Pharmacodynamics 4.3 (2012): 181-184.                                                              
Lakshmi, K. Muni Raja, M. Kiran, and K. Sai Prasanna. "A review on natural plants for phytochemical constituents and pharmacological activities." Journal of Drug Delivery and Therapeutics 11.2 (2021): 232-236.
6 Anthelmintic Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213.                                       

Durga, Nadella, and M. P. Padmaa. "Evaluation of anthelmintic activity of stem bark of Holoptelea integrifolia (Roxb) Planch." International Journal of Research in Ayurveda and Pharmacy (IJRAP) 1.2 (2010): 637-641.               

Kumar, Dinesh, et al. "A mini review on chemistry and biology of Holoptelea integrifolia Roxb. Planch (Ulmaceae)." Asian Pacific Journal of Tropical Biomedicine 2.2 (2012): S1200-S1205.                                                           
Pratap, Harendra, et al. "A study on anti-inflammatory activity of stem bark extract of Holoptelea integrifolia." Research Journal of Pharmacy and Technology 15.1 (2022): 77-81.                                                                                        
Bhuvad Sushama, B., and K. Nishteswar. "Ayurvedic and Ethno–botanical perspectives of chirabilva (Holoptelea Integrifolia Planch)." Int Ayurvedic Med J 1 (2013): 1-8.                                                                                                                
Dixit, Prateek, Mahesh Pal, and Dalip Upreti. "Comparative studies on the analytical and antioxidant activities of the medicinally important stem bark of Holoptelea integrifolia." JPC-Journal of Planar Chromatography-Modern TLC 27.3 (2014): 162-165.
                                                                                               
 Hassan, Amir, et al. "Identification of fatty acids and fatty acid esters from ethyl acetate bark extract of Holoptelea integrifolia (Roxb.) Planch by GC-MS." World J. of Pharm. Pharm. Sci 8.3 (2019): 164-174.                               
 Hassan, A., et al. "Identification of Five New Triterpenoids from Ethylacetate Bark Extract of Holoptelea integrifolia (Roxb.) Planch by GC-MS." Nat. Prod. Chem. Res 6.5 (2018): 338.                                                           
Petwal, Savita, Madhuri Kaushish Lily, and Koushalya Dangwal. "Holoptelea Integrifolia Bark And Leaves Phytochemicals, An Effective Ethno-Pharmacological Remedy For Treating Oral-Dental Infections.(2020)." Int J Pharm Sci 11.1: b43-50.
                                                                                                      
Patil, Kiran D., et al. "Potential of herbal constituents as new natural leads against helminthiasis: A neglected tropical disease." Asian Pacific Journal of Tropical Medicine 12.7 (2019): 291-299.
7 Antidiabetic Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213.                                  

 Kumar, Vijay, et al. "Green synthesis of silver nanoparticles using leaf extract of Holoptelea integrifolia and preliminary investigation of its antioxidant, anti-inflammatory, antidiabetic and antibacterial activities." Journal of Environmental Chemical Engineering 7.3 (2019): 103094.      

Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.
                                                                                                   
 Sajid, Mansuri, Goswami Raksha, and Jain Neetesh Kumar. "In vitro Alpha glucosidase and Aldolase reductase Inhibitory activity of Holoptelea integrifolia." Research Journal of Pharmacology and Pharmacodynamics 13.2 (2021): 35-40.                                                                                                                

Kumar, Vijay, et al. "High resolution GC/MS analysis of the Holoptelea integrifoli's leaves and their medicinal qualities." Biocatalysis and Agricultural Biotechnology 22 (2019): 101405.                                                         
Bhuvad Sushama, B., and K. Nishteswar. "Ayurvedic and Ethno–botanical perspectives of chirabilva (Holoptelea Integrifolia Planch)." Int Ayurvedic Med J 1 (2013): 1-8.                                                                                              
Subramanyam, P., T. Mohammad Munawar, and D. Muralidhara Rao. "PHYTOCHEMICAL ANALYSIS OF SOME COMPOUNDS FROM PLANT STEM BARK, LEAF AND FRUIT EXTRACTS OF HOLOPTELIA INTEGRIFOLIA." World Journal of Pharmaceutical Research (2017): 1070-1078.                                        

Hassan, A., et al. "Identification of Five New Triterpenoids from Ethylacetate Bark Extract of Holoptelea integrifolia (Roxb.) Planch by GC-MS." Nat. Prod. Chem. Res 6.5 (2018): 338.                                                            
Sutar, Ravindra C., M. Gowtham, and Girish A. Kashid. "Hptlc Finger Print Profile Of Steroids From Hydroalcohol Extract Of Leaves of Holoptelea Integrifolia (Roxb.)." Journal of Survey in Fisheries Sciences 10.4S (2023): 980-989.
8 Antidiarrhoeal Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213                             

Shrinivas, Sharma, K. S. Lakshmi, and T. Rajesh. "Evaluation of antidiarrhoeal potentials of ethanolic extract of leaves of Holoptelea integrifolia in mice model." International Journal of Pharmaceutical Research 1.3 (2009): 832-836.                                                                                                   

Kumar, Dinesh, et al. "A mini review on chemistry and biology of Holoptelea integrifolia Roxb. Planch (Ulmaceae)." Asian Pacific Journal of Tropical Biomedicine 2.2 (2012): S1200-S1205.                                                              
 Bhuvad Sushama, B., and K. Nishteswar. "Ayurvedic and Ethno–botanical perspectives of chirabilva (Holoptelea Integrifolia Planch)." Int Ayurvedic Med J 1 (2013): 1-8.                                                                                                         
 Pratap, Harendra, et al. "A study on anti-inflammatory activity of stem bark extract of Holoptelea integrifolia." Research Journal of Pharmacy and Technology 15.1 (2022): 77-81.                                                                                     
Solanki, Pooja, Dhruv Pandya, and Bharat Maitreya. "Antimicrobial activity of methanolic & aqueous extracts of leaves & young stem bark of Holoptelea integrifolia L." Int. J. Bot. Stud 5 (2020): 123-127.                     
 Veena, Hegde, et al. "Antibacterial and antidiarrheal activity of Simarouba amara (Aubl.) bark." Journal of Applied Pharmaceutical Science 9.5 (2019): 088-096.                                                                                                                                  
Baroda, S., and N. Chaturvedi. "Absence of hypolipidemic effect of Holoptelea integrifolia leaf extract in tyloxapol-induced hyperlipidemic rats." Journal of Pharmaceutical Negative Results 3.1 (2012): 16-21.
9 Adaptogenic Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213                                  

 Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                                  
Kumar, Dinesh, et al. "A mini review on chemistry and biology of Holoptelea integrifolia Roxb. Planch (Ulmaceae)." Asian Pacific Journal of Tropical Biomedicine 2.2 (2012): S1200-S1205.                                                           
Pratap, Harendra, et al. "A study on anti-inflammatory activity of stem bark extract of Holoptelea integrifolia." Research Journal of Pharmacy and Technology 15.1 (2022): 77-81.                                                                                        
 Kumar, Vijay, et al. "Phytochemical, analytical and medicinal studies of holoptelea integrifolia roxb. Planch-a review." Current Traditional Medicine 5.4 (2019): 270-277. 
10 Anticancer Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213                                         

 Lakshmi, K., et al. "Antitumour activity of ethanolic extract of leaves of Holoptelea integrifolia on Dalton's ascitic lymphoma in Swiss albino mice." International Journal of Green Pharmacy 4.1 (2010): 44.                                     
 Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                        
 Ibrahim, Magda T., Azza A. Shafei, and Fatema Mahrous. "Phytochemical and biological studies of natural Egyptian recipe with anticancer effect." IOSR J. Pharm. Biol. Sci 12 (2017): 29-39.                                                                            
Ahmed, Maryam, et al. "Triterpenoid antioxidant agents found in Holoptelea integrifolia (Roxb) Planch." International Journal of Pharmaceutical, Chemical and Biological Science 3 (2013): 63-67.              

Rizwani, Ghazala H., et al. "Anticancer Activity of Five Traditionally Used Medicinal Plants' Extracts." Journal of Cancer Research Updates 3.2 (2014): 103-107.                                                                                                                                 
Hassan, A., et al. "Identification of Five New Triterpenoids from Ethylacetate Bark Extract of Holoptelea integrifolia (Roxb.) Planch by GC-MS." Nat. Prod. Chem. Res 6.5 (2018): 338.                                                         
Munawar, T. Mohammad, D. Muralidhara Rao, and P. Subramanyam. "Antibacterial, antioxidant and anti-inflammatory potential of the different extracts of Holoptelia integrifolia." Int. J. Eng. Adv. Technol 9 (2019): 5234-5240.
                                                                                                                                       
Pratap, Harendra, et al. "A study on anti-inflammatory activity of stem bark extract of Holoptelea integrifolia." Research Journal of Pharmacy and Technology 15.1 (2022): 77-81.                                                                                  
Baroda, S., and N. Chaturvedi. "Absence of hypolipidemic effect of Holoptelea integrifolia leaf extract in tyloxapol-induced hyperlipidemic rats." Journal of Pharmaceutical Negative Results 3.1 (2012): 16-21.  
        
Sutar, Ravindra C., Sanjay B. Kasture, and V. K. Kalaichelvan. "Phytochemical Studies on the Glycosides of Leaf Extracts of Medicinally Important Plant Holoptelea integrifolia (Roxb.) Planch using High PerformanceThin Layer Chromatography." Asian J Pharm Clin Res 7.4 (2014): 192-196.
11 Wound Healing Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213                                  

Reddy, Boreddy Srinivas, et al. "Evaluation of antimicrobial, antioxidant and wound-healing potentials of Holoptelea integrifolia." Journal of Ethnopharmacology 115.2 (2008): 249-256.                                                                      
Somwong, Kanokwan, et al. "Effect of Holoptelea integrifolia (Roxb.) Planch. n-Hexane Extract and Its Bioactive Compounds on Wound Healing and Anti-Inflammatory Activity." Molecules 27.23 (2022): 8540.                
Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                               
 Jha, Megha, Versha Sharma, and Narayan Ganesh. "Antioxidant and wound healing potential of Pistia stratiotes L." Asian Pacific Journal of Tropical Disease 2 (2012): S579-S584.                                                                                                  
Alli, K. A. V. I. T. H. A., and Mangamoori Ln. "Comparative evaluation of antimicrobial activities of root, stem and leaves of Holoptelea integrifolia against pathogenic bacteria." Asian Jr. Of Microbiol. Biotech. Env. Sc 16.1 (2014): 145-154.                                                                                                                  

Süntar, Ipek, et al. "Wound healing and antioxidant properties: do they coexist in plants?." Free radicals and antioxidants 2.2 (2012): 1-7.                 

Sutar, Ravindra C., Sanjay B. Kasture, and V. K. Kalaichelvan. "Evaluation of antidepressant activity of leaf extracts of Holoptelea integri Folia (roxb) planch in experimental animals." Int J Pharm Pharm Sci 6.6 (2014): 250-253.  

Bhuvad, Sushama B., et al. "Comparative anti-inflammatory and analgesic activities of leaf powder and decoction of Chirabilva [Holoptelea integrifolia (Roxb.) Planch]." Ayu 35.3 (2014): 339.                                              
Dixit, Prateek, Mahesh Pal, and Dalip Upreti. "Comparative studies on the analytical and antioxidant activities of the medicinally important stem bark of Holoptelea integrifolia." JPC-Journal of Planar Chromatography-Modern TLC 27.3 (2014): 162-165.                                                                                              

Kokane, Dnyaneshwar D., et al. "Evaluation of wound healing activity of root of Mimosa pudica." Journal of ethnopharmacology 124.2 (2009): 311-315.
12 Hepatoprotective Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213                                        

 Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                                    
Hassan, A., et al. "A triterpenoid having anticancer activity found in stem bark of Holoptelea integrifolia (Roxb.) Planch." Nat Prod Chem Res 6.340 (2018): 2.                                                                                                                          
Munawar, T. Mohammad, D. Muralidhara Rao, and P. Subramanyam. "Antibacterial, antioxidant and anti-inflammatory potential of the different extracts of Holoptelia integrifolia." Int. J. Eng. Adv. Technol 9 (2019): 5234-5240.   
                                                                                                                               
 Kavitha, T., et al. "Ethnomedicinal plants survey in Kurunthamalai Hill, Coimbatore District, Tamil Nadu, India." Brazilian Journal of Biological Sciences 8.18 (2021): 57-72.                                                                          
Bhattacharya, Anshuman, et al. "Phytochemical and pharmacological evaluation of the seeds of Annona squamosa Linn." Int. J. Pharm. Sci 4 (2012): 92-94.                                                                                                          
Tirumalasetti, J., et al. "Protective effect of aqueous extract of Lagenaria siceraria (Molina) against maximal electroshock (MES)-induced convulsions in Albino Rats." Kathmandu Univ Med J 58.2 (2017): 117-20.                           
Singh, Sonia, Meenakshi Bajpai, and Pradeep Mishra. "Herbal Folklore Medication for Liver Disorders." Current Traditional Medicine 7.3 (2021): 415-433.                                                                                                                                   
Aswathy, G., et al. "Ayurvedic management of cirrhotic ascites." Ancient Science of Life 35.4 (2016): 236.
13 Larvicidal Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213                                        

 Kaushik, R., and P. Saini. "Screening of some semi-arid region plants for larvicidal activity against Aedes aegypti mosquitoes." J Vector Borne Dis 46.2009 (2009): 244-246.                                                                                               
Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                                   
Vinotha, Viswanathan, et al. "Biogenic synthesis of aromatic cardamom-wrapped zinc oxide nanoparticles and their potential antibacterial and mosquito larvicidal activity: An effective eco-friendly approach." Journal of Environmental Chemical Engineering 8.6 (2020): 104466.                        

 Chakraborty, Sumanta, et al. "Control of human filarial vector, Culex quinquefasciatus Say 1823 (Diptera: Culicidae) through bioactive fraction of Cayratia trifolia leaf." Asian Pacific Journal of Tropical Biomedicine 3.12 (2013): 980-984.
14 Antiemetic Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213                          

Shrinivas, Sharma, et al. "Ethanolic leaf extract of Holoptelea integrifolia, Planch. decreases cisplatin-induced pica in rats." Pharmacognosy Magazine 4.16 (2008): 293-297.                                                                                                           
 Shrinivas, Sharma, K. S. Lakshmi, and T. Rajesh. "Evaluation of antidiarrhoeal potentials of ethanolic extract of leaves of Holoptelea integrifolia in mice model." International Journal of Pharmaceutical Research 1.3 (2009): 832-836. 
15 CNS Depressant Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213.                               

 Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                           
Eloziia, N., et al. "A review on antidepressant plants." Journal of Pharmacy Research 11.5 (2017): 382-96.                                                                               

 Tirumalasetti, J., et al. "Protective effect of aqueous extract of Lagenaria siceraria (Molina) against maximal electroshock (MES)-induced convulsions in Albino Rats." Kathmandu Univ Med J 58.2 (2017): 117-20.                            
 Jaiswal, Bhagat Singh, and Mukul Tailang. "Phytochemistry and pharmacological profile of traditionally used medicinal plant Argyreia speciosa (Linn. f.)." Journal of Drug Delivery and Therapeutics 8.5-s (2018): 41-46. 
                                                                                                                            
Subramaniyan, Vetriselvan, and Velmurugan Paramasivam. "Potential anti-inflammatory activity of Plumbago zeylanica." Asian J Pharm Clin Res 10.10 (2017): 372-5. 
16 Hypolipidemic Activity Ganie, Showkat Ahmad, and Surender Singh Yadav. "Holoptelea integrifolia (Roxb.) Planch: a review of its ethnobotany, pharmacology, and phytochemistry." BioMed Research International Volume 2014, Article ID 401213, 12 pages http://dx.doi.org/10.1155/2014/401213.                             

 Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                                    
 Baroda, S., and N. Chaturvedi. "Absence of hypolipidemic effect of Holoptelea integrifolia leaf extract in tyloxapol-induced hyperlipidemic rats." Journal of Pharmaceutical Negative Results 3.1 (2012): 16-21.               
Valsaraj, Megha, et al. "Anti-Obesity Molecules from Plants and their Mode of Action." Anti-obesity Drug Discovery and Development 4 (2018): 197.       

Mamatha, M. K., U. S. Suma, and H. V. Annegowda. "The ascent of polyherbal formulation in the treatment of diabetes mellitus." Research Journal of Pharmacognosy and Phytochemistry 12.4 (2020): 256-260. 
17 Anti-arthritic activity Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                                        
Balima, N. Shinu, et al. "Anti-arthritic Effects of Bark Extracts of Holoptelea integrifolia (Roxb). Planch in a Chronic Inflammatory Model." Ind J Pure App Biosci 8 (2020): 103-108.                                                                                                         
Sadia, Sehrish, et al. "Ethnopharmacological profile of anti-arthritic plants of Asia-a systematic review." Journal of herbal medicine 13 (2018): 8-25.  

Sutar, RAVINDRA C., SANJAY B. Kasture, and V. K. Kalaichelvan. "Preliminary phytochemical screening and high performance thin layer chromatography fingerprint profile of leaf extracts of Holoptelea integrifolia (Roxb.) planch." Asian J Pharm Clin Res 7.4 (2014): 94-7.                                                    

 Rohilla, Pooja, Raghavendra Naik, and R. N. Acharya. "Single herbal remedies for Sandhivata (Osteoarthritis): A review on evidence based researches in Dravyaguna department of IPGT & RA, Jamnagar." Int J Herb Med 4.5 (2016): 97-101.                                                                                           

Subramoniam, A., V. Madhavachandran, and A. Gangaprasad. "Medicinal plants in the treatment of arthritis." Ann Phytomed 2.1 (2013): 3-36. 

 Jayawikrama, W. G. M. M., et al. "In vitro evaluation of antirheumatoid arthritic and anti-inflammatory activities of aqueous bark extract of Bridelia retusa." Journal of Pharmacognosy and Phytochemistry 7.3 (2018): 3234-3236. 
                                                                                                                                     
Sharma, A., et al. "Role of unripe Carica papaya linn. fruits on oxidative stress and hepatic glycogen content in experimentally induced diabetes in rats." Indian J Pharmacol 40 (2008): 2. 
18 Anticonvulsant activity Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                                        
Gangwar, Sudhir Singh, et al. "Screening of isolated phytosterol from leaves of Holoptelea integrifolia (Roxb.) Planch for it’ s anticonvulsant activity in experimental animals." Journal of Pharmacognosy and Phytochemistry 6.3 (2017): 657-661.                                                                           

Sajid, Mansuri, Goswami Raksha, and Jain Neetesh Kumar. "In vitro Alpha glucosidase and Aldolase reductase Inhibitory activity of Holoptelea integrifolia." Research Journal of Pharmacology and Pharmacodynamics 13.2 (2021): 35-40. 
                                                                                                         
 Adam, BALA A., and A. L. I. Y. U. Musa. "Anticonvulsant screening of methanol stem bark extract of Celtis integrifolia Lam (Ulmaceae) in mice and chicks." Journal of International Research in Medical and Pharmaceutical Sciences 10.4 (2016): 199-205. 
                                                     
Manasa, Megaravalli R., and Idoor D. Sachin. "Anticonvulsant action of aqueous extract of Centella asiatica and sodium valproate-A comparative study in pentylenetetrazole-induced seizures." National Journal of Physiology, Pharmacy and Pharmacology 6.2 (2016): 128.                                

 Odoh, Uchenna Estella, Dorothy Atteh Okwoli, and Felix Ngozi Osuala. "Studies on the Pharmacognostic Profiling and Anticonvulsant Activity of Morinda lucida Leaves Benth (Rubiaceae)." British Journal of Medical and Health Research 7.6 (2020): 45-68.                                                                              

Eloziia, N., et al. "A review on antidepressant plants." Journal of Pharmacy Research 11.5 (2017): 382-96.
                                                                                    
Jaiswal, Bhagat Singh, and Mukul Tailang. "Protective effect of ethanolic extract from the root of Argyreia speciosa against global cerebral ischemic reperfusion injury in rats." Journal of Drug Delivery and Therapeutics 8.6 (2018): 8-15. 
                                                                                                                       
Zimecki, Michał. "Potential impact of obligatory use of opioids in invasive procedures on interpretation of experimental data." Advances in Hygiene and Experimental Medicine 72 (2018): 52-57.                                                     
Kumar, Vijay. "Phytochemical, pharmacological activities and ayurvedic significances of magical plant Mimosa pudica Linn." Mini-Reviews in Organic Chemistry 18.3 (2021): 296-312. 
19 Antiulcer activity Mondal, S. U. M. I. T. A., and A. B. H. I. J. I. T. Bandyopadhyay. "The wonders of a medicinal tree: Holoptelea integrifolia (ROXB.) planch." Int J Pharm Pharm Sci 8.8 (2016): 43-8.                                                                                             
Hemamalini, K., et al. "Evaluation of Antiulcer activity of kigelia africana, Sophora interrupta and Holoptelea integrifolia in rats." International Journal of Research in Phytochemistry and Pharmacology 2.2 (2012): 84-89. 

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