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Anacyclus pyrethrum

BOTANICAL DETAILS OF PLANT

Synonyms

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Classification

Kingdom

Plantae

Subkingdom

Superdivision

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Division

Streptophyta

Class

Equisetopsida

Subclass

Magnoliidae

Order

Asterales

Family

Asteraceae

Genus

Anacyclus

Species

Anacyclus pyrethrum

Plant Description

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Habit/Life Form

--

DISTRIBUTION OF SPECIES IN INDIA

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Plant Parts Used

-

System of Medicine

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Intended Use

-

Traditional Application


Phytochemical Details

# Phytochemical Constituents PUBCHEM CID References
1 Pellitorin 5318516 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
2 Anacyclin 5281131 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
3 Phenylethylamine 1001 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
4 Levulinic Acid 11579 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
5 sesamin 72307 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
6 caryphyllene oxide 14350 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
7 cedryl acetate 13918856 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
8 Spathulenol 92231 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
9 Germacrene-D 91723653 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
10 Caryophylleneoxide 438558414 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
11 Caryophyllene-4 5322111 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
12 Malonic Acid 867 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
13 Pyrethrin I 5281045 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
14 Cinerin I 5281547 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
15 Jasmolin I 12304687 Usmani, Afreen, et al.
16 Chrysanthemum Acid 20755 Usmani, Afreen, et al.
17 Pyrethrin II 5281555 Usmani, Afreen, et al.
18 Cinerin II 5281548 Usmani, Afreen, et al.
19 Jasmolin II 12304690 Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
20 Jasmolin 1 12304687 Usmani, Afreen, et al.
21 Cinerolone 5374041 Usmani, Afreen, et al.
22 Jasmolone 5374699 Usmani, Afreen, et al.
23 Pyrethrins 1 6433154 Usmani, Afreen, et al.

Pharmacological Details

# PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES REFERENCES
1 Antioxidant Activity

Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.                                                             

Selles, Chaouki, et al. "Evaluation of antimicrobial and antioxidant activities of solvent extracts of Anacyclus pyrethrum L., from Algeria." Mediterranean journal of chemistry 2.2 (2012): 408-415.                                 

 Manouze, Houria, et al. "Anti-inflammatory, antinociceptive, and antioxidant activities of methanol and aqueous extracts of Anacyclus pyrethrum roots." Frontiers in pharmacology 8 (2017): 598.    

                        

Jawhari, Fatima Zahra, et al. "Anacyclus pyrethrum var. pyrethrum (L.) and Anacyclus pyrethrum var. depressus (Ball) Maire: Correlation between total phenolic and flavonoid contents with antioxidant and antimicrobial activities of chemically characterized Extracts." Plants 10.1 (2021): 149.   

Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.  

Shahrajabian, Mohamad H., S. U. N. Wenli, and Qi Cheng. "Spanish chamomile (Anacyclus pyrethrum) and pyrethrum (Tanacetum cineraiifolium): Organic and natural pesticides and treasure of medicinal herbs." Notulae Scientia Biologicae 13.1 (2021): 10816-10816.    

Jalayer, Naderi N., M. Niakan, and E. Khodadadi. "Determination of antibacterial activity of Anacyclus pyrethrum extract against some of the oral bacteria: an in vitro study." (2012): 59-63.                                                   

Riaz, M., et al. "In vitro antioxidant potential of selected aphrodisiac medicinal plants." Journal of biological regulators and homeostatic agents 31.2 (2017): 419-424.                                                                                     

Pandey, Sandeep, et al. "Chemical composition and medicinal uses of Anacyclus pyrethrum." Pharma science monitor 20189.1 (2018): 551-60.   

Pahuja, Monika, et al. "Root extract of Anacyclus pyrethrum ameliorates seizures, seizure-induced oxidative stress and cognitive impairment in experimental animals." Epilepsy research 98.2-3 (2012): 157-165.    

Jalayer-Naderi, Noushin, Mohammad Niakan, and Maryam Mohamadi-Motlagh. "The antibacterial activity of methanolic Anacyclus pyrethrum and Pistacia lentiscus L. extract on Escherichia coli." Iranian journal of microbiology 8.6 (2016): 372.                                                       

Sathasivampillai, Saravanan Vivekanandarajah, and Sujarajini Varatharasan. "Bioactivities Of Anacyclus pyrethrum (L.) Lag. extracts and natural products." Turkish Journal of Analytical Chemistry 2.2 (2020): 55-61.
2 Antidiabetic Activity Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.  
                                                                           
Tyagi, Satyanand, et al. "Antidiabetic effect of Anacyclus pyrethrum DC in alloxan induced diabetic rats." Eur. J. Biol. Sci 3.4 (2011): 117-120.  Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.
                                                                           
Elazzouzi, Hanane, et al. "Phytochemistry, Biological and Pharmacological Activities of the Anacyclus pyrethrum (L.) Lag: A Systematic Review." Plants 11.19 (2022): 2578.  
                                             
Kumar, V., and K. Lalitha. "In vitro study on [alpha]-amylase inhibitory activity of an Ayurvedic medicinal plant, Anacyclus pyrethrum DC root." Indian journal of pharmacology 46.3 (2014): 350.                                           
Selles, Chaouki, et al. "Evaluation of antimicrobial and antioxidant activities of solvent extracts of Anacyclus pyrethrum L., from Algeria." Mediterranean journal of chemistry 2.2 (2012): 408-415.   
           
Shahrajabian, Mohamad H., S. U. N. Wenli, and Qi Cheng. "Spanish chamomile (Anacyclus pyrethrum) and pyrethrum (Tanacetum cineraiifolium): Organic and natural pesticides and treasure of medicinal herbs." Notulae Scientia Biologicae 13.1 (2021): 10816-10816.   

Hachi, Maryama, et al. "Contribution to the ethnobotanical study of antidiabetic medicinal plants of the Central Middle Atlas region (Morocco)." Lazaroa 37.2016 (2016): 1-11. 
                                                   
 Kalam, M. A., et al. "Aqer qerha (Anacyclus pyrethrum DC.) a nobel drug of Unani system of medicine—A review." Int. J. Pharmacogn 2 (2015): 116-122. 
3 Immunostimulating Activity Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.                                                                         
Bendjeddou, D., K. Lalaoui, and D. Satta. "Immunostimulating activity of the hot water-soluble polysaccharide extracts of Anacyclus pyrethrum, Alpinia galanga and Citrullus colocynthis." Journal of ethnopharmacology 88.2-3 (2003): 155-160.   
                                                 
Sharma, Vikas, et al. "Immunomodulatory activity of petroleum ether extract of Anacyclus pyrethrum." Pharmaceutical biology 48.11 (2010): 1247-1254.                                                                                                                
Sujith, K., V. Suba, and C. Ronald Darwin. "Neuropharmacological profile of ethanolic extract of anacyclus Pyrethrum in Albino wistar rats." International Journal of Pharmaceutical Sciences and Research 2.8 (2011): 2109.                                                                                                        

Kerboua, Keltoum Alliouche, et al. "Anti-inflammatory and antioxidant activity of the hot water-soluble polysaccharides from Anacyclus pyrethrum (L.) Lag. roots." Journal of Ethnopharmacology 281 (2021): 114491.                                                                                                                      

Kalam, M. A., et al. "Aqer qerha (Anacyclus pyrethrum DC.) a nobel drug of Unani system of medicine—A review." Int. J. Pharmacogn 2 (2015): 116-122. 
4 Antidepressant activity Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.                                                                                         
 Kushwaha, Munna N., Vijay Singh Jatav, and Swatantra Pandey. "Plant Anacyclus pyrethrum-A review." Research Journal of Pharmacognosy and Phytochemistry 4.3 (2012): 164-170.                                                                                    
Bezza, Kenza, et al. "Effects of Anacyclus pyrethrum on affective behaviors and memory during withdrawal from cigarette smoke exposure in rats." Pharmacognosy Magazine 16.Suppl 1 (2020): S123-S132.                                        
Sujith, Kuttan, Ronald Darwin, and Venkatesan Suba. "Toxicological evaluation of ethanolic extract of Anacyclus pyrethrum in albino wistar rats." Asian Pacific Journal of Tropical Disease 2.6 (2012): 437-441.          
Kalam, M. A., et al. "Aqer qerha (Anacyclus pyrethrum DC.) a nobel drug of Unani system of medicine—A review." Int. J. Pharmacogn 2 (2015): 116-122. 

Ji, Ruifang, et al. "Simultaneous determination of five N-alkylamides in the root of Anacyclus pyrethrum by HPLC and profiling of components in its methanolic root extract by UPLC/Q-TOF-MS." Revista Brasileira de Farmacognosia 29.2 (2019): 152-161.   
                                                                        
Mishra, Amrita, et al. "Pharmacognostical, physicochemical and phytochemical studies of some marketed samples of roots used in Ayurvedic medicines." Pharmacognosy Journal 3.24 (2011): 55-61. 
5 Anticonvulsant activity Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.                                                                                              
Gautam, O. P., Savita Verma, and S. K. Jain. "Anticonvulsant and myorelaxation activity of Anacyclus pyrethrum DC.(Akarkara) root extract." Pharmacologyonline 1.1 (2011): 121-125.                                                                      
Yousef, Bashir A., et al. "Assessment of Anticonvulsant Activities of Petroleum Ether Extract of Anacyclus pyrethrum Roots on Experimental Rats." Pharmaceutical and Biomedical Research 7.1 (2021): 47-54.                      
 Elazzouzi, Hanane, et al. "Phytochemistry, Biological and Pharmacological Activities of the Anacyclus pyrethrum (L.) Lag: A Systematic Review." Plants 11.19 (2022): 2578.                                                                                                         
Pahuja, Monika, et al. "Effect of Anacyclus pyrethrum on pentylenetetrazole-induced kindling, spatial memory, oxidative stress and rho-kinase II expression in mice." Neurochemical research 38 (2013): 547-556.                                                                                                                                              
Baslam, Abdelmounaim, et al. "Modulation of Gut Microbiome in Ecstasy/MDMA-Induced Behavioral and Biochemical Impairment in Rats and Potential of Post-Treatment with Anacyclus pyrethrum L. Aqueous Extract to Mitigate Adverse Effects." International Journal of Molecular Sciences 24.10 (2023): 9086. 
                                                                                                        
  Manouze, Houria, et al. "Anticonvulsive and neuroprotective effects of aqueous and methanolic extracts of Anacyclus pyrethrum root in kainic acid-induced-status epilepticus in mice." Epilepsy Research 158 (2019): 106225.  
                                                                                                               
Sathasivampillai, Saravanan Vivekanandarajah, and Sujarajini Varatharasan. "Bioactivities Of Anacyclus pyrethrum (L.) Lag. extracts and natural products." Turkish Journal of Analytical Chemistry 2.2 (2020): 55-61.  
6 Memory-enhancing activity Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.                                                                                               
Sujith, K., C. Ronald Darwin, and V. Suba. "Memory-enhancing activity of Anacyclus pyrethrum in albino Wistar rats." Asian pacific journal of tropical disease 2.4 (2012): 307-311.                                                                                       
Mohammadi, Ali, et al. "Anacyclus pyrethrum extract exerts anticancer activities on the human colorectal cancer cell line (hct) by targeting apoptosis, metastasis and cell cycle arrest." Journal of gastrointestinal cancer 48 (2017): 333-340. 
                                                                                          
Avneet, Gupta, Singh Manish Pal, and Sisodia S. Siddhraj. "A review on herbal Ayurvedic medicinal plants and its association with memory functions." The Journal of Phytopharmacology 7.2 (2018): 162-6.  

Jamdhade, Vijay C., and BABASAHEB S. Surwase. "Memory enhancing activity of Taverniera cuneifolia (Roth) Arn: A substitute for commercial Liquorice." International Journal of Pharma & Bio Sciences 4 (2013): 277-285. Balasubramani, Subramani Paranthaman, et al. "Plant-based Rasayana drugs from Ayurveda." Chinese journal of integrative medicine 17.2 (2011): 88-94. 
                                                                                                                             
Qaiyyum, Ifra Abdul, Sameena Abdul Qayyum, and Mohd Afsahul Kalam. "MANAGEMENT OF FACIAL PALSY (LAQWA) THROUGH UNANI MEDICINE: A CASE SERIES." Ind. J. Unani Med 15.2 (2022): 102-107.                               
 Mahmood, Hafiz Khalid, et al. "Phytochemical and Antioxid ant Screening of Anacylus Pyrethrum, Apium Graveolens, Boerhaavia Diffusa, Cinnamomum Cassia Blume, Cuscumis Melo Linn, Cuscum is Sativus Linn, Daucus Sativus, Foeniculum Vulgare, Trachyspermum Ammii and Theit effect on various Human Ailments." Matrix Sci. Pharma 2.2 (2018): 06-14.  

                            
 Akanmu, A. O., et al. "Novelty-induced behavior and memory enhancing activities of aqueous and ethanol extracts of Solanum incanum Linn. fruits in mice." African Journal of Pharmacy and Pharmacology 15.2 (2021): 33-42. 

   Fatima, Sana, et al. "Preventive, promotive and curative aspects of dementia in complementary medicine (Unani): Through-Black Box Design." International Journal of Herbal Medicine 5 (2017): 1-5.
7 Aphrodisiacs Activity Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.                                                                                           
Sharma, Vikas, et al. "Evaluation of the anabolic, aphrodisiac and reproductive activity of Anacyclus pyrethrum DC in male rats." Scientia pharmaceutica 77.1 (2009): 97-110.                                                                          
Sharma, Vikas, et al. "Androgenic and spermatogenic activity of alkylamide‐rich ethanol solution extract of anacyclus pyrethrum DC." Phytotherapy Research 27.1 (2013): 99-106.                                                            
Pandey, Sandeep, et al. "Chemical composition and medicinal uses of Anacyclus pyrethrum." Pharma science monitor 20189.1 (2018): 551-60.     

Haghmorad, Dariush, et al. "Improvement of fertility parameters with Tribulus Terrestris and Anacyclus Pyrethrum treatment in male rats." International braz j urol 45 (2019): 1043-1054.                                                                 
Kalam, M. A., et al. "Aqer qerha (Anacyclus pyrethrum DC.) a nobel drug of Unani system of medicine—A review." Int. J. Pharmacogn 2 (2015): 116-122. 

 Vikas, Sharma, et al. "Effects of petroleum ether extract of Anacyclus pyrethrum DC. on sexual behavior in male rats." Journal of Chinese Integrative Medicine 8.8 (2010): 767-773.                                                                  
Dinki, Gugale, et al. "AQER QERHA (ANACYCLUS PYRETHRUM DC.) A NOBEL DRUG OF UNANI MEDICINE–A REVIEW." EPRA International Journal of Multidisciplinary Research (IJMR) 9.6 (2023): 294-306.                                      
Sujith, Kuttan, Ronald Darwin, and Venkatesan Suba. "Toxicological evaluation of ethanolic extract of Anacyclus pyrethrum in albino wistar rats." Asian Pacific Journal of Tropical Disease 2.6 (2012): 437-441. 
     
 Jawhari, Fatima Zahra, et al. "Anacyclus pyrethrum (L): Chemical composition, analgesic, anti-inflammatory, and wound healing properties." Molecules 25.22 (2020): 5469.                                                                                    
 Selles, Chaouki, et al. "Green corrosion inhibitor: Inhibitive action of aqueous extract of Anacyclus pyrethrum L. for the corrosion of mild steel in 0.5 M H2SO4." J. Mater. Environ. Sci 3.1 (2012): 206-219.
8 Antibacterial Activity Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.                                                                                              
Jawhari, Fatima Zahra, et al. "Anacyclus pyrethrum var. pyrethrum (L.) and Anacyclus pyrethrum var. depressus (Ball) Maire: Correlation between total phenolic and flavonoid contents with antioxidant and antimicrobial activities of chemically characterized Extracts." Plants 10.1 (2021): 149.   

 Jalayer, Naderi N., M. Niakan, and E. Khodadadi. "Determination of antibacterial activity of Anacyclus pyrethrum extract against some of the oral bacteria: an in vitro study." (2012): 59-63.                                                        
 Elazzouzi, Hanane, et al. "Phytochemical study of Anacyclus pyrethrum (L.) of Middle Atlas (Morocco), and in vitro study of antibacterial activity of pyrethrum." Advances in natural and applied sciences 8.8 (2014): 131-141.  

Jalayer-Naderi, Noushin, Mohammad Niakan, and Maryam Mohamadi-Motlagh. "The antibacterial activity of methanolic Anacyclus pyrethrum and Pistacia lentiscus L. extract on Escherichia coli." Iranian journal of microbiology 8.6 (2016): 372.   
                                                                                      
Pandey, Sandeep, et al. "Chemical composition and medicinal uses of Anacyclus pyrethrum." Pharma science monitor 20189.1 (2018): 551-60.       

Amine, Daoudi, et al. "Antibacterial activity of aqueous extracts of Anacyclus pyrethrum (L) Link and Corrigiola telephiifolia Pourr. from the middle atlas region-Morocco." Eur. Sci. J. ESJ 13 (2017): 116. 
     
 Shahrajabian, Mohamad H., S. U. N. Wenli, and Qi Cheng. "Spanish chamomile (Anacyclus pyrethrum) and pyrethrum (Tanacetum cineraiifolium): Organic and natural pesticides and treasure of medicinal herbs." Notulae Scientia Biologicae 13.1 (2021): 10816-10816.   
                 
  Tyagi, Sapna, et al. "Biosynthesis of silver nanoparticles using medicinal plant Anacyclus Pyrethrum and its antibacterial efficacy." Asian Journal of Research in Chemistry 11.3 (2018): 515-520.  
9 Local anesthetic Activity Usmani, Afreen, et al. "Pharmacognostic and phytopharmacology study of Anacyclus pyrethrum: An insight." Journal of Applied Pharmaceutical Science 6.3 (2016): 144-150.                                                                                            
Muralikrishnan, Kameshwaran, et al. "Comparative evaluation of the local anesthetic activity of root extract of Anacyclus pyrethrum and its interaction at the site of injection in guinea pigs." Anesthesia, essays and researches 11.2 (2017): 444.   
                                                                                        
 Elazzouzi, Hanane, et al. "Phytochemistry, Biological and Pharmacological Activities of the Anacyclus pyrethrum (L.) Lag: A Systematic Review." Plants 11.19 (2022): 2578.                                                                                                                     
Pandey, Sandeep, et al. "Chemical composition and medicinal uses of Anacyclus pyrethrum." Pharma science monitor 20189.1 (2018): 551-60.     

 Mohite, Vedangi Arvind, et al. "Comparative evaluation of a novel herbal anesthetic gel and 2% lignocaine gel as an intraoral topical anesthetic agent in children: Bilateral split-mouth, single-blind, crossover: in vivo: study." Journal of Indian society of pedodontics and preventive dentistry 38.2 (2020): 177-183.  
                                                                                                                
 Boonen, Jente, et al. "LC-MS N-alkylamide profiling of an ethanolic Anacyclus pyrethrum root extract." Planta Medica (2012): 1787-1795.     

  Akbar, Shahid, and Shahid Akbar. "Anacyclus pyrethrum (L.) Lag (Asteraceae/Compositae) (Syns.: A. depressus Ball; A. freynii Willk; A. officinarum Hayne; Anthemis pyrethrum L.)." Handbook of 200 Medicinal Plants: A Comprehensive Review of Their Traditional Medical Uses and Scientific Justifications (2020): 261-265.  
10 Anti-Inflammatory Activity Elazzouzi, Hanane, et al. "Phytochemistry, Biological and Pharmacological Activities of the Anacyclus pyrethrum (L.) Lag: A Systematic Review." Plants 11.19 (2022): 2578.                                                                                                                
Jawhari, Fatima Zahra, et al. "Anacyclus pyrethrum (L): Chemical composition, analgesic, anti-inflammatory, and wound healing properties." Molecules 25.22 (2020): 5469.                                                                                               
 Kerboua, Keltoum Alliouche, et al. "Anti-inflammatory and antioxidant activity of the hot water-soluble polysaccharides from Anacyclus pyrethrum (L.) Lag. roots." Journal of Ethnopharmacology 281 (2021): 114491.       
Manouze, Houria, et al. "Anti-inflammatory, antinociceptive, and antioxidant activities of methanol and aqueous extracts of Anacyclus pyrethrum roots." Frontiers in pharmacology 8 (2017): 598.                                 
 Jawhari, Fatima Zahra, et al. "Anacyclus pyrethrum var. pyrethrum (L.) and Anacyclus pyrethrum var. depressus (Ball) Maire: Correlation between total phenolic and flavonoid contents with antioxidant and antimicrobial activities of chemically characterized Extracts." Plants 10.1 (2021): 149.  

Selles, Chaouki, et al. "Evaluation of antimicrobial and antioxidant activities of solvent extracts of Anacyclus pyrethrum L., from Algeria." Mediterranean journal of chemistry 2.2 (2012): 408-415.                                
Pandey, Sandeep, et al. "Chemical composition and medicinal uses of Anacyclus pyrethrum." Pharma science monitor 20189.1 (2018): 551-60.      

Sathasivampillai, Saravanan Vivekanandarajah, and Sujarajini Varatharasan. "Bioactivities Of Anacyclus pyrethrum (L.) Lag. extracts and natural products." Turkish Journal of Analytical Chemistry 2.2 (2020): 55-61.    

Manouze, Houria, et al. "Anticonvulsive and neuroprotective effects of aqueous and methanolic extracts of Anacyclus pyrethrum root in kainic acid-induced-status epilepticus in mice." Epilepsy Research 158 (2019): 106225.     
                                                                                                           
 Muralikrishnan, Kameshwaran, et al. "Comparative evaluation of the local anesthetic activity of root extract of Anacyclus pyrethrum and its interaction at the site of injection in guinea pigs." Anesthesia, essays and researches 11.2 (2017): 444. 

Selles, Chaouki, et al. "Anti-diabetic activity of aqueous root extract of Anacyclus pyrethrum L. in streptozotocin-induced-diabetic rats." Journal of medicinal plants research 6.16 (2012): 3193-3198.
11 Insecticidal Activity Elazzouzi, Hanane, et al. "Phytochemistry, Biological and Pharmacological Activities of the Anacyclus pyrethrum (L.) Lag: A Systematic Review." Plants 11.19 (2022): 2578.                                                                                                           
Kushwaha, Munna N., Vijay Singh Jatav, and Swatantra Pandey. "Plant Anacyclus pyrethrum-A review." Research Journal of Pharmacognosy and Phytochemistry 4.3 (2012): 164-170.                                                                                 
 El Mokhtari, Kawtar, et al. "Chemical composition and insecticidal activity of Anacyclus pyrethrum essential oil from the Bensliman area against Culex pipiens." Mediterranean Journal of Chemistry 10.1 (2020): 13-21.          

 Shahrajabian, Mohamad H., S. U. N. Wenli, and Qi Cheng. "Spanish chamomile (Anacyclus pyrethrum) and pyrethrum (Tanacetum cineraiifolium): Organic and natural pesticides and treasure of medicinal herbs." Notulae Scientia Biologicae 13.1 (2021): 10816-10816.     

Selles, Chaouki, et al. "Evaluation of antimicrobial and antioxidant activities of solvent extracts of Anacyclus pyrethrum L., from Algeria." Mediterranean journal of chemistry 2.2 (2012): 408-415.                              
Burden, R. S., and L. Crombie. "Amides of vegetable origin. Part XII. A new series of alka-2, 4-dienoic tyramine-amides from Anacyclus pyrethrum DC (Compositae)." Journal of the Chemical Society C: Organic 19 (1969): 2477-2481.                                                                                                                                   

Crombie, L., and S. H. Harper. "Synthesis of a physiologically active compound of the pellitorine structure." Nature 164.4181 (1949): 1053-1054.  Greger, Harald. "Alkamides: Structural relationships, distribution and biological Activity1." Planta Medica 50.05 (1984): 366-375.

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