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Argemone mexicana

BOTANICAL DETAILS OF PLANT

Synonyms

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Classification

Kingdom

Plantae

Subkingdom

Superdivision

--

Division

Streptophyta

Class

Equisetopsida

Subclass

Magnoliidae

Order

Ranunculales

Family

Papaveraceae

Genus

Argemone

Species

Argemone mexicana

Plant Description

--

Habit/Life Form

--

DISTRIBUTION OF SPECIES IN INDIA

-

Plant Parts Used

-

System of Medicine

-

Intended Use

-

Traditional Application


Phytochemical Details

# Phytochemical Constituents PUBCHEM CID References
1 α-tocopherol 57393415 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
2 adenosine 60961 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
3 Isocorydine 10143 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
4 Berberine 2353 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
5 Dehydrocheilanthifoline 50817025 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
6 Dehydrocorydalmine 3083983 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
7 Jatrorrhizine 72323 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
8 Columbamine 72310 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
9 Coptisine 72322 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
10 (+)-reticuline 439653 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
11 Protopine 4970 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
12 Allocryptopine 98570 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
13 Cryptopine 72616 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
14 Muramine 288122 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
15 argemexicaine A 12624820 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
16 Phenylalanine 6140 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
17 protomexicine 21722040 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
18 scoulerine 22955 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
19 (+)-cheilanthifoline 440582 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
20 stylopine 6770 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
21 sanguinarine 5154 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
22 chelerythrine 2703 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.

Pharmacological Details

# PHARMACOLOGICAL ACTIONS/THERAPEUTIC USES REFERENCES
1 Anti-HIV activity

Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                         

Chang, Yuh-Chwen, et al. "Two new protopines argemexicaines A and B and the anti-HIV alkaloid 6-acetonyldihydrochelerythrine from formosan Argemone mexicana." Planta medica 69.02 (2003): 148-152.                             

Sabde, Sudeep, et al. "Anti-HIV activity of Indian medicinal plants." Journal of natural medicines 65 (2011): 662-669.  

                                                            

Jaiswal, Jyotsna, et al. "Analysis of Biochemical and Antimicrobial Properties of Bioactive Molecules of Argemone mexicana." Molecules 28.11 (2023): 4428.                                                                                                                    

Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90.     

 Joshi, Nupur, et al. "Phytochemical screening of secondary metabolites of Argemone mexicana linn. flowers." Int J Curr Pharm Res 5.2 (2013): 144-147.  Khan, Aisha Saleem, and Aisha Saleem Khan. "Woody plants with possible anti-HIV activity." Medicinally important trees (2017): 109-131.   

               

Rubio-Piña, Jorge, and Felipe Vázquez-Flota. "Pharmaceutical applications of the benzylisoquinoline alkaloids from Argemone mexicana L." Current Topics in Medicinal Chemistry 13.17 (2013): 2200-2207.                                      

Thorat, Vishal Hindurao, and Sachin Ghorpade. "Argemone mexicana Linn. having medicinal property." Int J Pharmacogn 5.2 (2018): 82-90.               

Chang, Yuh-Chwen, et al. "Cytotoxic benzophenanthridine and benzylisoquinoline alkaloids from Argemone mexicana." Zeitschrift für Naturforschung C 58.7-8 (2003): 521-526.     
2 Anti-inflammatory activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                                 
Teklie Mengie Ayele, Endeshaw Chekol Abebe, Zelalem Tilahun Muche, Melaku Mekonnen Agidew, Yohannes Shumet Yimer, Getu Tesfaw Addis, Nega Dagnaw Baye, Achenef Bogale Kassie, Muluken Adela Alemu, Tesfagegn Gobezie Yiblet, Gebrehiwot Ayalew Tiruneh, Samuel Berihun Dagnew, "Evaluation of In Vivo Wound-Healing and Anti-Inflammatory Activities of Solvent Fractions of Fruits of Argemone mexicana L. (Papaveraceae)", Evidence-Based Complementary and Alternative Medicine, vol. 2022, Article ID 6154560, 17 pages, 2022. https://doi.org/10.1155/2022/6154560 

Ibrahim, H. A., et al. "Analgesic and anti-inflammatory studies on the roots Argemone mexicana Linn (Family: Papaveraceae)." J Pharm Biol Sci 11.3 (2016): 92-5.  
                          
Khan, Aziz Mohammad, and Seema Bhadauria. "Analysis of medicinally important phytocompounds from Argemone mexicana." Journal of King Saud University-Science 31.4 (2019): 1020-1026.                                                    
 Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90.  

Joshi, Nupur, et al. "Phytochemical screening of secondary metabolites of Argemone mexicana linn. flowers." Int J Curr Pharm Res 5.2 (2013): 144-147. Malik, Chandani, et al. "Phytochemistry and pharmacology of Argemone mexicana Linn-An Indian medicinal plant." Res. J. Pharm. Phytochem 15 (2023): 27-32. 
                                                                                                       
Dash, G. K., and P. N. Murthy. "Evaluation of Argemone mexicana Linn. Leaves for wound healing activity." J Nat Prod Plant Resour 1.1 (2011): 46-56.                                                                                                                        
 Prasad, Mergu, and Satya Prasad Venugopal. "Preliminary phytochemical analysis and oral acute toxicity study of the root of Argemone mexicana (Linn)." Int J Res Dev Pharmacy Life Sci 5.2 (2016): 2010-2017.                                                                                             
Monterrosas‐Brisson, Nayeli, et al. "Effect of Argemone mexicana on Local Edema and LPS‐Induced Neuroinflammation." Chemistry & Biodiversity 18.3 (2021): e2000790.                           

Prasad, Mergu, and Satya Prasad Venugopal. "Preliminary phytochemical analysis and oral acute toxicity study of the root of Argemone mexicana (Linn)." Int J Res Dev Pharmacy Life Sci 5.2 (2016): 2010-2017.
3 Wound healing activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.  
                                                                       
 Dash, G. K., and P. N. Murthy. "Evaluation of Argemone mexicana Linn. Leaves for wound healing activity." J Nat Prod Plant Resour 1.1 (2011): 46-56.                                          

Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143.              

 Andleeb, Shahla, et al. "In-vitro antibacterial and antifungal properties of the organic solvent extract of Argemone mexicana L." Journal of King Saud University-Science 32.3 (2020): 2053-2058.   

 Saravanan, R., et al. "Evaluation of wound healing and anti microbial activity of the Argemone mexicana linn (Papavraceae)." Research Journal of Pharmacy and Technology 10.6 (2017): 852-857. 
       
 Dev, Suresh Kumar, et al. "Antimicrobial, anti-inflammatory and wound healing activity of polyherbal formulation." Biomedicine & Pharmacotherapy 111 (2019): 555-567.   
                                  
 Pathak, Ranjana, Anjana Goel, and S. C. Tripathi. "Medicinal property and ethnopharmacological activities of Argemone mexicana: an overview." Annals of the Romanian Society for Cell Biology (2021): 1615-1641.                                                                                                      

Singh, A., et al. "Green synthesis of silver nanoparticles using Argemone mexicana leaf extract and evaluation of their antimicrobial activities." Dig J Nanomater Bios 5.2 (2010): 483-489.  

 Malik, Chandani, et al. "Phytochemistry and pharmacology of Argemone mexicana Linn-An Indian medicinal plant." Res. J. Pharm. Phytochem 15 (2023): 27-32.   
                                        
Joshi, Nupur, et al. "Phytochemical screening of secondary metabolites of Argemone mexicana linn. flowers." Int J Curr Pharm Res 5.2 (2013): 144-147.                                                                                                                                                    
Gupta, S., et al. "Wound healing activity of polyherbal formulation on excision based wound model in mice." Plant Archives 8.2 (2008): 783-785.                                                                                                                                                 
Nayak, Praveen, Durga Madhab Kar, and Laxmidhar Maharana. "Antidiabetic activity of aerial parts of Argemone mexicana Linn. in alloxan induced hyperglycaemic rats." Pharmacologyonline 1 (2011): 889-903.                                                                                                                                     
Gupta, Nilesh, and U. Jain. "Prominent wound healing properties of indigenous medicines." Journal of Natural Pharmaceuticals 1.1 (2010): 2-2.         

 Palanikumar, Pandi, et al. "Effect of Argemone mexicana active principles on inhibiting viral multiplication and stimulating immune system in Pacific white leg shrimp Litopenaeus vannamei against white spot syndrome virus." Fish & shellfish immunology 75 (2018): 243-252.
4 Anti-stress and antiallergic activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                           
Alam, Afroz, and Adnan A. Khan. "Argemone mexicana L.: A weed with versatile medicinal and pharmacological applications." Annals of Phytomedicine: International Journal 9.1 (2020): 218-223.                                  
Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90. 

 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                                  
 Thorat, Vishal Hindurao, and Sachin Ghorpade. "Argemone mexicana Linn. having medicinal property." Int J Pharmacogn 5.2 (2018): 82-90.        

 Anarthe, Sneha, and Sanjay Chaudhari. "Neuropharmacological study of Argemone mexicana Linn." Journal of Applied Pharmaceutical Science Issue (2011): 121-126.                                                                                                
 Abou-Elnaga, Zeinab Sh. "Strong larvicidal properties of Argemone mexicana L. against medically important vectors Culex pipiens and Aedes aegypti." International Journal of Mosquito Research 2.1 (2015): 09-12.          

Devanathan, Krishnamoorthy. "Argemone mexicana L. Papaveraceae." Ethnobotany of the Mountain Regions of Southeast Asia (2020): 1-13.         

Das, Tuyelee, Samapika Nandy, and Abhijit Dey. "Asthma-Induced Inflammatory Responses and Reversal by Botanicals." Medicinal Plants for Lung Diseases: A Pharmacological and Immunological Perspective (2021): 103-125.  

Rayees, Sheikh, et al. "Traditional Plants with Anti-asthmatic Potential." Asthma: Pathophysiology, Herbal and Modern Therapeutic Interventions (2021): 39-42.                                                                                          
Dahanukar, S. A., R. A. Kulkarni, and N. N. Rege. "Pharmacology of medicinal plants and natural products." Indian journal of pharmacology 32.4 (2000): S81-S118.                                                                                                                              
 Oriola, Ayodeji Oluwabunmi, and Adebola Omowunmi Oyedeji. "Plant-derived natural products as lead agents against common respiratory diseases." Molecules 27.10 (2022): 3054.
5 Vasoconstrictor and vasorelaxant effects Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                 
Rubio-Piña, Jorge, and Felipe Vázquez-Flota. "Pharmaceutical applications of the benzylisoquinoline alkaloids from Argemone mexicana L." Current Topics in Medicinal Chemistry 13.17 (2013): 2200-2207.                         
Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                 
Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90.              

Mackraj, I., Thirumala Govender, and Prem Gathiram. "Sanguinarine." Cardiovascular Drug Reviews 26.1 (2008): 75-83.                                                

Mushtaq, Zarina, et al. "Berberine: a comprehensive Approach to combat human maladies." International Journal of Food Properties 26.1 (2023): 787-807.   
6 Anti-fertility activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567. 
                                                                       
 Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90.              

Maurya, R., et al. "Traditional remedies for fertility regulation." Current medicinal chemistry 11.11 (2004): 1431-1450.                                                     

Sandey, Kamini, et al. "Production and optimization of antibacterial metabolites from endophytic fungi Nigrospora sp. ML# 3." Journal of Applied Pharmaceutical Science 5.11 (2015): 031-037.                                       
Bhatia, Manisha, N. Siddiqui, and Sumeet Gupta. "Abrus precatorius (L.): An evaluation of traditional herb." J Pharm Res 3 (2013): 3296-315.                    

 Yadav, Prity, et al. "Potential antifertility and antimicrobial activities of plants used in traditional medicines: A review." Journal of Pharmacognosy and Phytochemistry 12.2 (2023): 190-198.                                                         
Khatun, Asha, et al. "Ethnomedicinal usage of plants and animals by folk medicinal practitioners of three villages in Chuadanga and Jhenaidah districts, Bangladesh." Am-Eur J Sustain Agr 7 (2013): 319-39.                                 
Viswanathan, N., and B. S. Joshi. "Toxic Constituents of some Indian plants." Current Science 52.1 (1983): 1-8.         

Salunkhe, D. K., R. N. Adsule, and K. I. Bhonsle. "Antifertility agents of plant origin." Toxicants of plant origin. IV. phenolics. CRC Press, Boca Raton (1989): 53-81.                             

Alam, Gulzar, Manjul Pratap Singh, and Anita Singh. "Wound healing potential of some medicinal plants." International journal of Pharmaceutical sciences Review and Research 9.1 (2011): 136-145
7 Mollucicidal activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.  
                                                                            
Singh, Sushma, and D. K. Singh. "Effect of molluscicidal components of Abrus precatorius, Argemone mexicana and Nerium indicum on certain biochemical parameters of Lymnaeu acuminata." Phytotherapy Research 13.3 (1999): 210-213.                                                                                                      

Alam, Afroz, and Adnan A. Khan. "Argemone mexicana L.: A weed with versatile medicinal and pharmacological applications." Annals of Phytomedicine: International Journal 9.1 (2020): 218-223.                                      
Singh, Sushma, and D. K. Singh. "Molluscicidal activity of Abrusprecatorius linn. and Argemonemexicana linn." Chemosphere 38.14 (1999): 3319-3328.           

Singh, S., and D. K. Singh. "Effect of Active Molluscicidal Componenets Of Abrus Precatorius, Argemone Mexicana And Nerium Indicum On Certain Enzymes In The Nervous Tissue Of Lymnaea Acuminata." (2000): 187-194.     

Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90.           

Telkar, Sanjay N., et al. "Evaluation of Diuretic Activity of Argemone mexicana." Research Journal of Pharmacology and Pharmacodynamics 10.3 (2018): 105-108.                                                                                                                      
Ali, Hasan, et al. "Lethal action of Argemone mexicana L. extracts against Culex quinquefasciatus Say larvae and Tribolium castaneum (Hbst.) adults." Journal of Pharmacognosy and Phytochemistry 6.1 (2017): 438-441.         

Singh, Priyamvada, Vinay K. Singh, and Dinesh K. Singh. "Effect of binary combination of some plant‐derived molluscicides with MGK‐264 or piperonyl butoxide on the reproduction of the snail Lymnaea acuminata." Pest Management Science: formerly Pesticide Science 61.2 (2005): 204-208.  

Das, Prabhat, et al. "Pharmacological efficacy of Argemone mexicana plant extract, against cysteamine-induced duodenal ulceration in rats." Indian Journal of Medical Sciences 65.3 (2011): 92.      

 Orhan, Ilkay, et al. "Antiviral and antimicrobial profiles of selected isoquinoline alkaloids from Fumaria and Corydalis species." Zeitschrift für Naturforschung C 62.1-2 (2007): 19-26.      
8 Antihelmintic activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                                 
Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143. 
                                                                                                            
 Jaliwala, Y. A., et al. "In vitro anthelmintic activity of aerial parts of Argemone mexicana Linn." J Pharm Res 4.9 (2011): 3173-3174.  
                                      
Díaz, Gabriela Jasso, et al. "In vitro assessment of Argemone mexicana, Taraxacum officinale, Ruta chalepensis and Tagetes filifolia against Haemonchus contortus nematode eggs and infective (L3) larvae." Microbial Pathogenesis 109 (2017): 162-168.
                                                                          
Apu, Apurba Sarker, et al. "Phytochemical analysis and bioactivities of Argemone mexicana Linn. leaves." Pharmacology online 3 (2012): 16-23.           

 Elizondo-Luévano, Joel H., et al. "In vitro antischistosomal activity of the Argemone mexicana methanolic extract and its main component berberine." Iranian Journal of Parasitology 16.1 (2021): 91.  

Elizondo-Luevano, Joel Horacio, et al. "In vitro effect of methanolic extract of Argemone mexicana against Trichomonas vaginalis." The Korean Journal of Parasitology 58.2 (2020): 135. 
                                         
Chaity, Farjana Rahman, Mohammad A. Rashid, and Mohammad Sharifur Rahman. "Biological Investigations of the Whole Plant of Argemone mexicana (L.)." Dhaka University Journal of Pharmaceutical Sciences 20.1 (2021): 135-138.  
                                                                          
Aguilar, Hector Hugo Galicia, et al. "In vitro nematocidal activity of plant extracts of Mexican flora against Haemonchus contortus fourth larval stage." Annals of the New York Academy of Sciences 1149.1 (2008): 158-160.      

Osho, A., and T. Adetunji. "Antimicrobial activity of the essential oil of Argemone mexicana Linn." Journal of Medicinal Plants Research 4.1 (2010): 19-22.  
                                                                                                  
Dhaker, Sanjay K., Vivek Jain, and Dileep Bharati. "Spleno protective activity of Argemone mexicana Linn. against aniline induced splenic toxicity in rats." Research Chronicle in Health Sciences 1.1 (2015): 60-67.         

Devanathan, Krishnamoorthy. "Argemone mexicana L. Papaveraceae." Ethnobotany of the Mountain Regions of Southeast Asia (2020): 1-13.
9 Larvicidal activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                           
Granados-Echegoyen, Carlos A., et al. "Argemone mexicana (Papaverales: Papavaraceae) as an alternative for mosquito control: First report of larvicidal activity of flower extract." Journal of medical entomology 56.1 (2019): 261-267.   
                                                                                                                   
Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143.  
                                                                                            
Vetal, D. S., and A. B. Pardeshi. "Larvicidal potential of Argemone mexicana L. Plant extracts against Spodoptera litura fab." The Pharma Innovation Journal 8.6 (2019): 698-702.                                                                                                
Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90.           

Sakthivadivel, M., and D. Thilagavathy. "Larvicidal and chemosterilant activity of the acetone fraction of petroleum ether extract from Argemone mexicana L. seed." Bioresource technology 89.2 (2003): 213-216.                    

Ali, Hasan, et al. "Lethal action of Argemone mexicana L. extracts against Culex quinquefasciatus Say larvae and Tribolium castaneum (Hbst.) adults." Journal of Pharmacognosy and Phytochemistry 6.1 (2017): 438-441.              

 Kamalakannan, Siva, et al. "Bio Fabrication of Silver Nanoparticle from Argemone mexicana for the Control of Aedes albopictus and their Antimicrobial Activity." Current Pharmaceutical Biotechnology 17.14 (2016): 1285-1294.                                                                                                                           

Kavitha, G., J. Gokulakrishnan, and M. Baranitharan. "Biosynthesis of silver nanoparticles using Argemone mexicana: A novel route of malarial fever vector mosquito control." Biochemical and Cellular Archives 20 (2020): 3267-3274.    
                                                                                                                    
  Sakthivadivel, Murugesan, and Thilagavathy Daniel. "Evaluation of certain insecticidal plants for the control of vector mosquitoes viz. Culex quinquefasciatus, Anopheles stephensi and Aedes aegypti." Applied Entomology and Zoology 43.1 (2008): 57-63.
10 Antioxidant activity  Perumal, P., et al. "In vitro antioxidant activity of Argemone mexicana roots." International Journal of PharmTech Research 2.2 (2010): 1477-1482. 

 Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143.   
                                                                                                               
Datkhile, Kailas D., et al. "Studies on phytoconstituents, in vitro antioxidant, antibacterial and cytotoxicity potential of Argemone mexicana Linn.(family: Papaveraceae)." J. Nat. Sci. Biol. Med 11 (2020): 198-205.      
Apu, Apurba Sarker, et al. "Phytochemical analysis and bioactivities of Argemone mexicana Linn. leaves." Pharmacology online 3 (2012): 16-23.     

 Orozco-Nunnelly, Danielle Annette, et al. "Characterizing the cytotoxic effects and several antimicrobial phytocompounds of Argemone mexicana." Plos one 16.4 (2021): e0249704. 
                                                
Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                                           
Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90.        

Dev, Suresh Kumar, et al. "Phytochemical characterization and antioxidant assessment of herbal extracts." Journal of Drug Delivery and Therapeutics 8.4 (2018): 126-133.                                                                                                            
 Singh, Mandeep, et al. "Effect of metal contaminants and antioxidants on the oxidation stability of Argemone mexicana biodiesel: experimental and statistical study." Waste and Biomass Valorization 11 (2020): 6189-6198.       

Arcos-Martínez, Aideé Itzel, et al. "Anxiolytic-like effect of ethanolic extract of Argemone mexicana and its alkaloids in Wistar rats." Avicenna Journal of Phytomedicine 6.4 (2016): 476.                                                                             
Pathak, Ranjana, Anjana Goel, and S. C. Tripathi. "Medicinal property and ethnopharmacological activities of Argemone mexicana: an overview." Annals of the Romanian Society for Cell Biology (2021): 1615-1641.           
Dash, G. K., and P. N. Murthy. "Evaluation of Argemone mexicana Linn. Leaves for wound healing activity." J Nat Prod Plant Resour 1.1 (2011): 46-56.
11 Anticancer activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                       
More, Nilesh V., and Arun S. Kharat. "Antifungal and anticancer potential of argemone mexicana L." Medicines 3.4 (2016): 28.                                     

 Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90. 
                                                   
Gacche, Rajesh N., Rafik U. Shaikh, and Mahesh M. Pund. "In vitro evaluation of anticancer and antimicrobial activity of selected medicinal plants from Ayurveda." Asian J Trad Med 6.3 (2011): 1-7.                                   
Verma, Satish Kumar, et al. "In vitro cytotoxicity of Argemone mexicana against different human cancer cell lines." International Journal of Chemical Environmental and Pharmaceutical Research 1.1 (2010): 37-39. 
     
Orozco-Nunnelly, Danielle Annette, et al. "Characterizing the cytotoxic effects and several antimicrobial phytocompounds of Argemone mexicana." Plos one 16.4 (2021): e0249704.                                                         
Malik, Chandani, et al. "Phytochemistry and pharmacology of Argemone mexicana Linn-An Indian medicinal plant." Res. J. Pharm. Phytochem 15 (2023): 27-32.                                                                                                                   
Datkhile, Kailas D., et al. "Studies on phytoconstituents, in vitro antioxidant, antibacterial and cytotoxicity potential of Argemone mexicana Linn.(family: Papaveraceae)." J. Nat. Sci. Biol. Med 11 (2020): 198-205.     
Prasad, Mergu, and Satya Prasad Venugopal. "Preliminary phytochemical analysis and oral acute toxicity study of the root of Argemone mexicana (Linn)." Int J Res Dev Pharmacy Life Sci 5.2 (2016): 2010-2017.              
 Kushtwar, Raveendra Singh, and Subhasish Tripathy. "Study on antifungal activity of aerial part of Argemone mexicana Linn." World J Pharm Res 6.6 (2017): 1025-1031.  
                                                                         
Venkatesan, Balaji, et al. "Rapid synthesis of biocompatible silver nanoparticles using aqueous extract of Rosa damascena petals and evaluation of their anticancer activity." Asian Pacific journal of tropical medicine 7 (2014): S294-S300.                               

Tariq, Akash, Sakina Mussarat, and Muhammad Adnan. "Review on ethnomedicinal, phytochemical and pharmacological evidence of Himalayan anticancer plants." Journal of ethnopharmacology 164 (2015): 96-119.              
12 Antidiabetic activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                                            
Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143. 
                                                                                                                 
Nayak, Praveen, Durga Madhab Kar, and Laxmidhar Maharana. "Antidiabetic activity of aerial parts of Argemone mexicana Linn. in alloxan induced hyperglycaemic rats." Pharmacologyonline 1 (2011): 889-903.                           

Pathak, Ranjana, Anjana Goel, and S. C. Tripathi. "Medicinal property and ethnopharmacological activities of Argemone mexicana: an overview." Annals of the Romanian Society for Cell Biology (2021): 1615-1641.                         

 Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90.    

Morey, P. R., et al. "A Review on Argemone maxicana Linn." Research Journal of Pharmacognosy and Phytochemistry 15.2 (2023): 149-154.  
                                                                                        
 Motilal, Bairagi Shripad, Inayat B. Pathan, and Nema Nitin. "Evaluación de la actividad diurética y laxante del extracto acuoso de hojas de Argemone mexicana en ratas." Ars Pharmaceutica (Internet) 58.2 (2017): 53-58.     
                                                                                                          
Dénou, Adama, et al. "Isolation, characterisation and complement fixation activity of acidic polysaccharides from Argemone mexicana used as antimalarials in Mali." Pharmaceutical Biology 60.1 (2022): 1278-1285.       

Tilak, Amita, et al. "Screening of leaf extracts of Argemone Mexicana for its antiarthritic activity in experimental animals." World Journal of Pharmaceutical Research 7.3 (2017): 1054-1063. 
                                    
Mathur, C. H. A. R. U. T. A., and R. Gupta. "A review on medicinal plants of rajasthan having antidiabetic activity." Asian J Pharm Clin Res 11.12 (2018): 33-39.                                                                                                    
Chaity, Farjana Rahman, Mohammad A. Rashid, and Mohammad Sharifur Rahman. "Biological Investigations of the Whole Plant of Argemone mexicana (L.)." Dhaka University Journal of Pharmaceutical Sciences 20.1 (2021): 135-138.                                         

Rubio-Piña, Jorge, and Felipe Vázquez-Flota. "Pharmaceutical applications of the benzylisoquinoline alkaloids from Argemone mexicana L." Current Topics in Medicinal Chemistry 13.17 (2013): 2200-2207.       
13 Antihepatotoxic activity Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.
                                                                       
Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143.                                

Adam, S. I. Y., et al. "Evaluation of hepatoprotective activity of Argemone mexicana aerial Part Extracts on CCL_4 induced liver damage in wistar rats." British Journal of Pharmacology and Toxicology 2.5 (2011): 251-256. 

Malik, Chandani, et al. "Phytochemistry and pharmacology of Argemone mexicana Linn-An Indian medicinal plant." Res. J. Pharm. Phytochem 15 (2023): 27-32.                                                                                                      
Sourabie, T. S., J. B. Nikiema, and O. G. Nacoulma. "Monographycal survey of pharmacological potentials of Argemone mexicana L.(Papaveraceae), a plant of Burkina Faso Pharmacopeia: determination of antihepatotoxic and antipyretic activities." Int J Res Pharm Biosci 1 (2014): 1-10.
                  
Thorat, Vishal Hindurao, and Sachin Ghorpade. "Argemone mexicana Linn. having medicinal property." Int J Pharmacogn 5.2 (2018): 82-90.           

Kiran Chilivery, Ravi, Sangilimuthu Alagar, and Teepica P Darsini. "In Vitro Anti-Urolithiasis Potentials of Argemone mexicana L. Leaves." Current Clinical Pharmacology 11.4 (2016): 286-290.                                           
 Jain, Sanjay Kumar, et al. "Herbal extract as hepatoprotective-A review." Journal of Pharmacognosy and Phytochemistry 2.3 (2013): 170-175. 

Anarthe, Sneha, and Sanjay Chaudhari. "Neuropharmacological study of Argemone mexicana Linn." Journal of Applied Pharmaceutical Science Issue (2011): 121-126.                                                                                         
Ravi Kiran, Chilivery, et al. "Intrinsic evaluation of antiurolithiatic capacity of argemone mexicana L. In wistar albino rats." Journal of Herbs, Spices & Medicinal Plants 27.3 (2021): 289-304. 
                          
 Morey, P. R., et al. "A Review on Argemone maxicana Linn." Research Journal of Pharmacognosy and Phytochemistry 15.2 (2023): 149-154.  

  Kavitha, G., J. Gokulakrishnan, and M. Baranitharan. "Biosynthesis of silver nanoparticles using Argemone mexicana: A novel route of malarial fever vector mosquito control." Biochemical and Cellular Archives 20 (2020): 3267-3274.                                                                              
14 Muscle relaxtant activity Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143.   
                                                                                                         
Anarthe, Sneha, and Sanjay Chaudhari. "Neuropharmacological study of Argemone mexicana Linn." Journal of Applied Pharmaceutical Science Issue (2011): 121-126.                                                                                                      
 Morey, P. R., et al. "A Review on Argemone maxicana Linn." Research Journal of Pharmacognosy and Phytochemistry 15.2 (2023): 149-154.                   

 Magos-Guerrero, Gil Alfonso, Jacinto Santiago-Mejía, and Omar F. Carrasco. "Exploratory studies of some Mexican medicinal plants: cardiovascular effects in rats with and without hypertension." Journal of intercultural ethnopharmacology 6.3 (2017): 274. 
                                                                      
Ricardo, Torres-González Omar, et al. "Argemone ochroleuca: Biology, Pharmacological Potential and Perspectives." Journal of Nutrition and Growth 4.1 (2018): 14-17.                                                                                
Arias-Durán, Luis, et al. "Tracheal relaxation through calcium channel blockade of Achillea millefolium hexanic extract and its main bioactive compounds." Journal of ethnopharmacology 253 (2020): 112643.                 
 Jain, SACHIN KUMAR, S. U. M. I. T. Parihar, and N. E. H. A. Pandey. "Medicinal plants with neuropharmacological properties from Indian origin." Int J Pharm Pharm Sci 6.10 (2014): 36-40.     
15 Analgesic Activity Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143.  
                                                                                                    
Pathak, Ranjana, Anjana Goel, and S. C. Tripathi. "Medicinal property and ethnopharmacological activities of Argemone mexicana: an overview." Annals of the Romanian Society for Cell Biology (2021): 1615-1641.                   

Anarthe, Sneha, and Sanjay Chaudhari. "Neuropharmacological study of Argemone mexicana Linn." Journal of Applied Pharmaceutical Science Issue (2011): 121-126.                                                                                            
 Sarkar, Kishore Kumar, et al. "Phytochemical screening and evaluation of the pharmacological activities of ethanolic extract of Argemone mexicana Linn. aerial parts." Oriental Pharmacy and Experimental Medicine 19 (2019): 91-106.
                                                                                                                   
 Brahmachari, Goutam, Dilip Gorai, and Rajiv Roy. "Argemone mexicana: chemical and pharmacological aspects." Revista Brasileira de Farmacognosia 23 (2013): 559-567.                                                                                           
Malik, Chandani, et al. "Phytochemistry and pharmacology of Argemone mexicana Linn-An Indian medicinal plant." Res. J. Pharm. Phytochem 15 (2023): 27-32.                                                                                                       
 Apu, Apurba Sarker, et al. "Phytochemical analysis and bioactivities of Argemone mexicana Linn. leaves." Pharmacology online 3 (2012): 16-23.   

Morey, P. R., et al. "A Review on Argemone maxicana Linn." Research Journal of Pharmacognosy and Phytochemistry 15.2 (2023): 149-154.             

Chang, Yuh-Chwen, et al. "Cytotoxic benzophenanthridine and benzylisoquinoline alkaloids from Argemone mexicana." Zeitschrift für Naturforschung C 58.7-8 (2003): 521-526.   
16 Locomotor Activity Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143. 
                                                                                                        
Anarthe, Sneha, and Sanjay Chaudhari. "Neuropharmacological study of Argemone mexicana Linn." Journal of Applied Pharmaceutical Science Issue (2011): 121-126.                                                                                                
Nancy, A., and A. Praveena. "Argemone mexicana: A boon to medicinal and pharmacological approaches in current scenario." Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Cardiovascular & Hematological Agents) 15.2 (2017): 78-90.   

Asuntha, G., et al. "Pharmacological profiling of Argemone mexicana for its aphrodisiac potentials in male Wistar rats." Asian Pacific Journal of Reproduction 3.2 (2014): 110-115.                                                             
 Kalpana, S., et al. "Study of Central Nervous System Depressant and Behavioral Activity of Ethanolic Extract of Clitoria Annuain Albino Rats." International Journal of Health Care and Biological Sciences (2023): 63-68.   
Tripathi, Payal. "The adverse effect of toxic plant constituent found in India: forensic approach." Pharm Innov 10.3 (2021): 35-44.   
17 Expectorant Activity Pathak, Ranjana, Anjana Goel, and S. C. Tripathi. "Medicinal property and ethnopharmacological activities of Argemone mexicana: an overview." Annals of the Romanian Society for Cell Biology (2021): 1615-1641.        
      
Priya, Charles Lekhya, and Kokati Venkata Bhaskara Rao. "Ethanobotanical and current ethanopharmacological aspects of Argemone mexicana Linn: an overview." International Journal of Pharmaceutical Sciences and Research 3.7 (2012): 2143. 
                                                                                                    
 Kiran Chilivery, Ravi, Sangilimuthu Alagar, and Teepica P Darsini. "In Vitro Anti-Urolithiasis Potentials of Argemone mexicana L. Leaves." Current Clinical Pharmacology 11.4 (2016): 286-290.                                                                      
Joshi, Nupur, et al. "Phytochemical screening of secondary metabolites of Argemone mexicana linn. flowers." Int J Curr Pharm Res 5.2 (2013): 144-147. 

Andleeb, Shahla, et al. "In-vitro antibacterial and antifungal properties of the organic solvent extract of Argemone mexicana L." Journal of King Saud University-Science 32.3 (2020): 2053-2058.                                                  
Alam, Afroz, and Adnan A. Khan. "Argemone mexicana L.: A weed with versatile medicinal and pharmacological applications." Annals of Phytomedicine: International Journal 9.1 (2020): 218-223.  
                     
Elizondo-Luevano, Joel Horacio, et al. "In vitro effect of methanolic extract of Argemone mexicana against Trichomonas vaginalis." The Korean Journal of Parasitology 58.2 (2020): 135.                                                                            
Malik, Chandani, et al. "Phytochemistry and pharmacology of Argemone mexicana Linn-An Indian medicinal plant." Res. J. Pharm. Phytochem 15 (2023): 27-32. 

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Annual Consumption (in MT)

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Adulterant/Substitute

CULTIVARS AND VARIETIES

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